A5101865007- Axial and Atropisomeric Chirality Synthesis
- Heavy metals in environment
- Molecular spectroscopy and chirality
- Heavy Metal Exposure and Toxicity
- Alkaloids: synthesis and pharmacology
- Pharmacological Effects of Natural Compounds
- Water Quality Monitoring and Analysis
- Medicinal plant effects and applications
- Child Abuse and Trauma
- Melamine detection and toxicity
- Air Quality and Health Impacts
- Identification and Quantification in Food
- Gout, Hyperuricemia, Uric Acid
- Migration, Health and Trauma
- Synthesis and biological activity
- Polyamine Metabolism and Applications
- Sphingolipid Metabolism and Signaling
- Child and Adolescent Psychosocial and Emotional Development
- Spectroscopy and Chemometric Analyses
- Quinazolinone synthesis and applications
- Drug Transport and Resistance Mechanisms
Shandong University
2024
Second Hospital of Shandong University
2024
North Sichuan Medical University
2024
Huazhong University of Science and Technology
2017-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Guang’anmen Hospital
2021
Ministry of Ecology and Environment
2017
Abstract Reported here is the first catalytic atroposelective electrophilic amination of indoles, which delivers functionalized atropochiral N ‐sulfonyl‐3‐arylaminoindoles with excellent optical purity. This reaction was furnished by 1,6‐nucleophilic addition to p ‐quinone diimines. Control experiments suggest an ionic mechanism that differs from radical pathway commonly proposed for 1,6‐addition quinones. The origin selectivity investigated through computational studies. Preliminary studies...
Abstract Reported here is the first catalytic atroposelective electrophilic amination of indoles, which delivers functionalized atropochiral N ‐sulfonyl‐3‐arylaminoindoles with excellent optical purity. This reaction was furnished by 1,6‐nucleophilic addition to p ‐quinone diimines. Control experiments suggest an ionic mechanism that differs from radical pathway commonly proposed for 1,6‐addition quinones. The origin selectivity investigated through computational studies. Preliminary studies...
In this study, the role of traditional Chinese medicine (TCM) in relieving epidermal growth factor receptor-tyrosine kinase inhibitor- (EGFR-TKI-) associated diarrhea was discussed by network pharmacology and data mining. Prediction drug targets introducing EGFR-TKI molecular structures into SwissTargetPrediction platform diarrhea-related DrugBank, GeneCards, DisGeNET, OMIM databases were obtained. Compounds drug-disease target intersection screened absorption, distribution, metabolism,...
Shugan Lidan Xiaoshi Granules (SLXG) is a traditional Chinese medicine (TCM) formulation frequently employed to prevent and treat cholesterol gallstones. SLXG formulated based on the Chaihu Formula found in an ancient medical book, remedy China for centuries, has demonstrated successful treatment of numerous patients with gallbladder stones.
Background Addressing the long-term physical and mental health impacts of adverse childhood experiences (ACEs) remains a significant public challenge. Additionally, ACEs can contribute to intergenerational transmission, affecting future generations. While previous studies have primarily focused on children adolescents, there is limited data ACE subtypes influencing factors among general adult population, particularly in China. This study aims explore prevalence, subtypes, Chinese adults....