A5045216500- Cancer Research and Treatments
- Nanoplatforms for cancer theranostics
- Autophagy in Disease and Therapy
- Infection Control in Healthcare
- Essential Oils and Antimicrobial Activity
- Synthesis of Organic Compounds
- Phagocytosis and Immune Regulation
- Skin Protection and Aging
- Plant-Microbe Interactions and Immunity
- Transgenic Plants and Applications
- Ginger and Zingiberaceae research
- Korean Peninsula Historical and Political Studies
- Proteoglycans and glycosaminoglycans research
- Radiation Therapy and Dosimetry
- Connexins and lens biology
- Retinoids in leukemia and cellular processes
- Plant Pathogens and Fungal Diseases
- Plant tissue culture and regeneration
- Marine Sponges and Natural Products
- Aquaculture disease management and microbiota
- Phytochemistry and Biological Activities
- Redox biology and oxidative stress
- Natural product bioactivities and synthesis
- Migration, Ethnicity, and Economy
- Antimicrobial Peptides and Activities
The Wistar Institute
2023-2025
National Sun Yat-sen University
2019-2022
Manila Central University
2017-2018
Pampanga State Agricultural University
2015
Immunotherapy is becoming a popular treatment modality in combat against cancer, one of the world's leading health problems. While tumor cells influence host immunity via expressing immune inhibitory signaling proteins, some bacteria possess immunomodulatory activities that counter symptoms tumors. The accumulation Salmonella sites influences protein expression, resulting T cell infiltration. However, molecular mechanism by which activates remains elusive. Many tumors have been reported to...
Heparanase cleaves the extracellular matrix by degrading heparan sulfate that ultimately leads to cell invasion and metastasis; a condition causes high mortality among cancer patients.Many of anticancer drugs available today are natural products plant origin, such as hinokitiol.In previous report, it was revealed hinokitiol plays an essential role in anti-inflammatory anti-oxidation processes promote apoptosis or autophagy resulting inhibition tumor growth differentiation.Therefore, this...
Thyroid cancer has been known as the most common endocrine malignancy. Although majority of thyroid types respond well to conventional treatment including surgery and radioactive iodine therapy, about 10% those with differentiated will present distant metastasis have persistent or recurrent disease. Even more serious is a rare type called anaplastic (ATC), which accounts for 1%, demonstrated lethal aggressive form human Unfortunately, these tumors are also frequently resistant traditional...
Context: The study investigated the medicinal properties of Spathiphyllum cannifolium (Dryand. ex Sims) Schott as a possible source antimicrobial compounds. Materials and Methods: phytochemical constituents were screened using qualitative methods antibacterial antifungal activities determined agar well diffusion method. Statistical Analysis: One-way analysis variance Fisher's least significant difference test used. Results: screening showed presence sterols, flavonoids, alkaloids, saponins,...
Chemotherapy is now in common use for the treatment of tumors; however, with tumor growth retardation comes severe side effects that occur after a chemotherapy cycle.Eicosapentaenoic acids (EPA) used combination has an additive and provides rationale using EPA tandem chemotherapy.To improve efficacy safety this therapy, further understanding modulates microenvironment necessary.Connexin 43 (Cx43) involved enhancing chemosensitivity was suppressed microenvironment.We aim to investigate role...
Targeting metastasis is a vital strategy to improve the clinical outcome of cancer patients, specifically in cases with high-grade malignancies. Here, we employed Salmonella-based treatment address metastasis. The potential Salmonella as an anticancer agent has been extensively studied; however, mechanism through which it affects remains unclear. This study found that epithelial-to-mesenchymal transition (EMT) inducer SNAI1 was markedly reduced Salmonella-treated melanoma cells, revealed by...
Chemotherapy is a treatment method commonly used for cancer and that patients showing low to no response the often developed drug resistance via multiple mechanisms. Natural products have been shown reduce tumor resistance. Hinokitiol, natural tropolone derivative, has potential as an antitumor agent. To improve efficacy safety of hinokitiol, further understanding hinokitiol interactions with microenvironment necessary. The presence plasma membrane multidrug protein P-glycoprotein (P-gp)...
Robust antimicrobial coatings featuring high transparency, strong bactericidal activity, and an easy application procedure on generic surfaces can be widely accepted by the public to prevent pandemics. In this work, we demonstrated hand-sprayer-based approach deposit complex oxide composed of Co-Mn-Cu-Zn-Ag screen protectors smartphones through acidic redox-assisted deposition (ARD). The as-obtained possess transparency (99.74% transmittance at 550 nm) long-lasting durability against swiping...
This descriptive research was undertaken to unveil the perception of local farmers in Magalang, Pampanga towards GM crops with aid a written survey instrument administered respondents from February March 2014.In general, it observed that despite inadequate information regarding crops, their implication and impact on human health, environment economy, ambivalent view about improved nutritional quality other health benefits consider safe for consumption solution food security. The are very...
Introduction: The study was carried out to isolate and identify potential antibiotic-producing bacteria associated with water cabbage (Pistia stratiotes) roots collected from Pampanga River, Pampanga, Philippines. Seven (7) bacterial colonies were randomly chosen at the 10-6 dilution factor. Antibiotic sensitivity test using agar well method revealed that only one of 7 selected can inhibit growth organisms. Specifically, (namely T4) supernatant inhibited E. coli B. subtilis but not S....
Abstract The expression of EMT inducer Snail in many cancer types has been implicated high-grade malignancies and correlated with poor prognosis. Tumor-intrinsic not only direct effects on metastasis but also impacts tumor microenvironment by altering secretomes. Our previous reports demonstrated that systemic administration Salmonella significantly reduced growth metastatic nodules tumor-bearing mice, part, coaxing changes the microenvironment. These led us to hypothesize targets inducers....
Robust antimicrobial coatings featuring high transparency, strong bactericidal activity, and easy application procedure on generic surfaces can be widely accepted by the public to prevent pandemics. In this work, we demonstrated hand sprayer-based approach deposit complex oxide composed of Co-Mn-Cu-Zn-Ag screen protectors smartphones through acidic redox-assisted deposition (ARD). The as-obtained possess transparency (99.74% transmittance at 550 nm) long-lasting durability against swiping...
Robust antimicrobial coatings featuring high transparency, strong bactericidal activity, and easy application procedure on generic surfaces can be widely accepted by the public to prevent pandemics. In this work, we demonstrated hand sprayer-based approach deposit complex oxide composed of Co-Mn-Cu-Zn-Ag screen protectors smartphones through acidic redox-assisted deposition (ARD). The as-obtained possess transparency (99.74% transmittance at 550 nm) long-lasting durability against swiping...