A5103133372- Wheat and Barley Genetics and Pathology
- Genetic Mapping and Diversity in Plants and Animals
- Plant nutrient uptake and metabolism
- Plant Stress Responses and Tolerance
- Crop Yield and Soil Fertility
- Plant Molecular Biology Research
- Genetics and Plant Breeding
- Plant Micronutrient Interactions and Effects
- Plant Disease Resistance and Genetics
- Mycobacterium research and diagnosis
- Biocrusts and Microbial Ecology
- Photosynthetic Processes and Mechanisms
- Cancer-related molecular mechanisms research
- Phytase and its Applications
- Agriculture, Soil, Plant Science
- Agriculture, Plant Science, Crop Management
- RNA modifications and cancer
- Genomics and Phylogenetic Studies
- Agricultural Productivity and Crop Improvement
- Yeasts and Rust Fungi Studies
- Algal biology and biofuel production
- RNA Research and Splicing
- Plant Pathogens and Fungal Diseases
- Mycotoxins in Agriculture and Food
- Polymer-Based Agricultural Enhancements
Gansu Agricultural University
2016-2025
First Affiliated Hospital of Jinan University
2022-2025
Jinan University
2024-2025
Ningbo University
2022-2025
Guangdong Academy of Medical Sciences
2018-2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
2022
Chengdu University of Technology
2022
Guangdong General Hospital
2018
Abstract Background Quantitative polymerase chain reaction (QPCR) is a widely applied analytical method for the accurate determination of transcript abundance. Primers QPCR have been designed on genomic scale but non-specific amplification non-target genes has frequently problem. Although several online databases created storage and retrieval experimentally validated primers, only few thousand primer pairs are currently present in existing primers not use under common PCR thermal profile....
Currently, it is still a tough task for dentists to remineralize dentine in deep caries. The aim of this study was demineralized tooth model caries using nanocomplexes carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) based on mimicking the stabilizing effect matrix protein 1 (DMP1) ACP biomineralization dentine. experimental results indicate that CMC can stabilize form CMC/ACP, which able be processed into scaffolds by lyophilization. In single-layer collagen model, nanoparticles...
Very little is known about the adaptation mechanism of Chenopodiaceae Halogeton glomeratus, a succulent annual halophyte, under saline conditions. In this study, we investigated morphological and physiological mechanisms seedlings exposed to different concentrations NaCl treatment for 21 d. Our results revealed that H. glomeratus has robust ability tolerate salt; its optimal growth occurs approximately 100 mm Salt crystals were deposited in water-storage tissue We speculate osmotic...
Oxidative stress plays a critical role in postmenopausal osteoporosis, yet its impact on osteoblasts remains underexplored, limiting therapeutic advances. Our study identifies phospholipid peroxidation as key feature of osteoporosis. Estrogen regulates the transcription glutathione peroxidase 4 (GPX4), an enzyme crucial for reducing peroxides osteoblasts. The deficiency estrogen reduces GPX4 expression and increases Inhibition or knockout impairs osteoblastogenesis, while elimination rescues...
Model organisms have contributed substantially to our understanding of the etiology human disease as well having assisted with development new treatment modalities. The availability human, mouse and, most recently, rat genome sequences now permit comprehensive investigation rodent orthologs genes associated disease. Here, we investigate whether differ significantly from their respect overall levels conservation and rates evolutionary change.Human are unevenly distributed among chromosomes...
A lack of phosphorus (P) in plants can severely constrain growth and development. Barley, one the earliest domesticated crops, is extensively planted poor soil around world. To date, molecular mechanisms enduring low phosphorus, at transcriptional level, barley are still unclear. In present study, two different genotypes (GN121 GN42)-with contrasting efficiency-were used to reveal adaptations stress, three time points, morphological, physiological, biochemical, transcriptome level. GN121 was...
Halogeton glomeratus (H. glomeratus) is an extreme halophyte that widely distributed in arid regions, including foothills, the Gobi desert of northwest China, and marginal loess Central Asia. However, research on salt-tolerant mechanisms genes this species are limited because a lack genomic sequences. In present study, transcriptome H. was analyzed using next-generation sequencing technology to identify involved salt tolerance better understand response glomeratus.
Soil salinity severely threatens land use capability and crop yields worldwide. An analysis of the molecular mechanisms salt tolerance in halophytes will contribute to development salt-tolerant crops. In this study, a combination physiological characteristics iTRAQ-based proteomic approaches was conducted investigate underlying response suspension cell cultures halophytic Halogeton glomeratus. These cells showed growth responses comparable those whole plant. total, 97 up-regulated proteins...
Panicle development is an important agronomic trait that aids in determining crop productivity. Foxtail millet and its wild ancestor green foxtail have recently been used as model systems to dissect gene functions. Here, we characterized a recessive mutant of millet, loose-panicle 1 (lp1), which showed pleiotropic phenotypes, such lax primary branching pattern, aberrant branch morphology, semi-dwarfism, enlarged seed size. The loose panicle phenotype was attributed increased lengths...
Plant height (PH) and yield components are important traits for improvement in wheat breeding. In this study, 207 F2:4 recombinant inbred lines (RILs) derived from the cross Jingdong 8/Aikang 58 were investigated under limited full irrigation environments at Beijing Gaoyi, Hebei province, during 2011–12 2012–13 cropping seasons. The RILs genotyped with 149 polymorphic simple sequence repeat (SSR) markers, quantitative trait loci (QTLs) PH analysed by inclusive composite interval mapping. All...
Under climate change, drought is one of the most limiting factors that influences wheat (Triticum aestivum L.) production. Exploring stress-related genes vital for breeding. To identify related to tolerance response, two common cultivars, Zhengmai 366 (ZM366) and Chuanmai 42 (CM42), were selected based on their obvious difference in root length under 15% PEG-6000 treatment. The ZM366 cultivar was significantly longer than CM42. Stress-related identified by RNA-seq samples treated with 7...
Osteosarcoma is one of the most prevalent bone malignancies with a poor prognosis. The N7-methylguanosine (m7G) modification facilitates RNA structure and function tightly associated cancer. Nonetheless, there lack joint exploration relationship between m7G methylation immune status in osteosarcoma.With support TARGET GEO databases, we performed consensus clustering to characterize molecular subtypes based on regulators all osteosarcoma patients. least absolute shrinkage selection operator...
Planting halophytes is a widely used method of phytoremediation for saline soils. The succulent Halogeton glomeratus and Suaeda glauca are remediation soil in the arid region Northwestern China. However, whether intercropping H. S. can increase improvement effect yet to be proved. Therefore, this study analyzed three planting modes: monocropping (Hg), (Sg), (Hg||Sg). These were applied field experiments, with biomass physicochemical properties measured each treatment, mechanism was using...
Barley leaf stripe, caused by Pyrenophora graminea, significantly reduces yield. Polygalacturonase, a key fungal pectinase, facilitates cell wall degradation for nutrition acquisition and colonization. To determine whether P. graminea contains polygalacturonase (PgPG)-encoding genes their role in pathogenicity, four PgPG (PgPG1–PgPG4) were identified the genome. Quantitative RT-PCR revealed that PgPG1 had highest inducible expression during barley infection, suggesting its critical vital...
Introduction Inorganic phosphorus (Pi) is an indispensable nutrient for plant growth, with phosphate transporter proteins (PHTs) having key roles in Pi uptake, transport, and signal transduction plants. However, a systematic comprehensive genomic analysis of the wheat PHT family (covering PHT1-5 PHO1 ) lacking. Methods In view this, we successfully identified 180 Triticum aestivum ( TaPHT members 6 families using bioinformatics, performed in-depth phylogenetic analyses between these protein...
Talaromycosis, caused by Talaromyces marneffei (T. marneffei), has become more common in HIV-negative and immunocompetent patients. The fungus colonizes the body through dormant spores, causing opportunistic infections. Early diagnosis is challenging. This study aims to analyze clinical features, diagnosis, treatment, prognosis of T. Patients diagnosed with infection or colonization at People's Hospital Ningbo University between August 2022 July 2024 were included. Demographic...
Lycium ruthenicum Murray (LR) , known as “black goji berry” or wolfberry”, is widely utilized in chinese herbal medicine. LR fruit showed its antioxidant and/or anti-inflammation activity treating cardiac injury, experimental colitis, nonalcoholic fatty liver disease, fatigue, and aging. Glaucoma the leading cause of irreversible blindness. Besides elevated intraocular pressure (IOP), oxidative stress neuroinflammation were recognized to contribute pathogenesis glaucoma. This study...
Common wheat production is significantly influenced by abiotic stresses. Identifying the genetic loci for seedling root traits and developing available molecular markers are crucial breeding high yielding stable varieties. In this study, five traits, including length (RL), surface area (RA), volume (RV), number of tips (RT), dry weight (RW), were measured in Wp-072/Wp-119 recombinant inbred line (RIL) population. Genotyping was conducted RIL population their parents using 90K...
Human adipose-derived stem cells (hADSCs) are seed with application prospects in cartilage repair. However, the mechanism of hADSC chondrogenic differentiation is still unclear. This study identifies a novel circRNA, circNR3C2, which significantly upregulated during hADSCs. To analyze their role differentiation, hADSCs were separated and identified by flow cytometry. Thereafter, we conducted Alcian Blue staining to assess levels. Additionally, RT-qPCR was carried out detect levels...