A5051767609- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Renal cell carcinoma treatment
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Gastrointestinal Tumor Research and Treatment
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Pancreatic function and diabetes
- Cancer, Lipids, and Metabolism
- Renal Transplantation Outcomes and Treatments
- Neuroblastoma Research and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Multiple and Secondary Primary Cancers
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Sarcoma Diagnosis and Treatment
- Nutrition and Health in Aging
- Mesenchymal stem cell research
- Cancer Genomics and Diagnostics
Kobe University
2013-2025
Kobe University Hospital
2013-2023
Seirei Mikatabara General Hospital
2018-2020
Yodogawa Christian Hospital
2019
Tokai University
2017
Yonsei University
2014
Centre Hospitalier Universitaire de Nantes
2014
Beckman Research Institute
2008-2011
City of Hope
2008-2011
Southern California Reproductive Center
2007
Bone marrow-derived mesenchymal stem cells (MSCs) are known to produce vascular endothelial growth factor. We hypothesize that co-transplantation of MSCs and islets promotes revascularization improves islet graft function.Lewis rat were infused into the liver streptozotocin-diabetic syngeneic recipients or transplanted under renal capsule nonobese diabetic severe combined immunodeficiency (NOD SCID) mice with isolated from Lewis bone marrow expanded in culture.Co-transplantation 500 107...
Background and Objectives Pylorus‐preserving pancreatoduodenectomy (PPPD) has been associated with a high incidence of delayed gastric emptying (DGE). There are few studies comparing DGE PPPD subtotal stomach‐preserving (SSPPD). Moreover, differences between the procedures respect to long‐term results have not reported. A prospective randomized study was conducted compare perioperative complications nutritional status SSPPD. Methods One hundred patients periampullary lesions were receive...
Expression of B lymphocyte-induced maturation protein 1 (Blimp-1) transcription factor is essential for promoting cell differentiation into plasma cells. However, a critical Blimp-1 expression in activated cells unclear. When splenic were stimulated with CD40 ligand (CD40L) and IL-4, terminal was induced the from c-fos transgenic (H2-c-fos) mice but barely those control littermates c-fos-deficient mice. AP-1 family mRNAs transiently cells, overexpression c-Fos sufficient amount H2-c-fos...
Induction of hematopoietic chimerism and subsequent donor-specific immune tolerance via bone marrow transplantation is an ideal approach for islet to treat type-1 diabetes. We examined the potential mesenchymal stem cells (MSCs) in induction allograft without incidence graft-versus-host disease (GVHD). Streptozotocin-diabetic rats received a conditioning regimen consisting antilymphocyte serum 5 Gy total body irradiation, followed by intraportal co-infusion allogeneic MSCs, (BMCs) islets....
The study assessed the initial experience with posterior tibial nerve stimulation (PTNS) for faecal incontinence and compared it sacral (SNS) performed in a single centre during same timespan.A retrospective review of prospectively collected database was conducted at colorectal unit, University Hospital, Nantes, France, from May 2009 to December 2010. Seventy-eight patients diagnosed chronic severe underwent neurostimulation including PTNS 21 SNS 57. main outcome measures were (Wexner score)...
Background. The activation of p38 mitogen-activated protein kinases (MAPK) is implicated in cold ischemia-reperfusion injury donor organs. islet isolation process, from pancreas procurement through collection, may activate p38MAPK leading to cytokine release and damage. This damage be prevented by treating pancreata with a inhibitor (p38IH) before preservation. Methods. Pancreata removed Beagle dogs were infused University Wisconsin solution containing the p38IH, SB203580, Pefabloc (n=6) or...
Autoimmune pancreatitis (AIP) is a rare disease that closely mimics pancreatic cancer (PC) in its presentation. It very important for clinicians to distinguish one from the other because their treatment and prognosis are vastly different. Typical radiological imaging findings, particular observation of diffusely or segmentally narrowed main duct (MPD) with an irregular wall by endoscopic retrograde cholangiopancreatography (ERCP), essential making diagnosis AIP. On hand, MPD obstruction most...