A5055032466- RNA modifications and cancer
- Sperm and Testicular Function
- Urinary Bladder and Prostate Research
- Cancer-related molecular mechanisms research
- Spine and Intervertebral Disc Pathology
- Gut microbiota and health
- Skin Diseases and Diabetes
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Dietary Effects on Health
- Restless Legs Syndrome Research
- Inflammasome and immune disorders
- Ovarian function and disorders
- Ginger and Zingiberaceae research
- Diabetes Treatment and Management
- Hydrocarbon exploration and reservoir analysis
- Pancreatic function and diabetes
- Reproductive Biology and Fertility
- Spinal Cord Injury Research
- Pregnancy-related medical research
- Reproductive Physiology in Livestock
- Sesame and Sesamin Research
Hubei University of Science and Technology
2025
Hunan University of Traditional Chinese Medicine
2025
Henan Agricultural University
2023-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Objective Non-SMC condensin II complex subunit D3 (NCAPD3) has recently been demonstrated as a crucial oncogenic factor, nevertheless, the biological role of NCAPD3 in pathogenesis breast cancer not elucidated. Evidence suggests that targeting ferroptosis can inhibit progression cancer. Moreover, 2,3,5,4’-Tetrahydroxystilbene-2-O-β-D-glucoside (THSG) could modulate MCF-7 cell proliferation our previous study. Therefore, we aimed to investigate potential mechanism by which mediates THSG...
Fasting-induced molting (FIM) is a common method used to improve the laying performance of aged hens. Nevertheless, this approach may impose various stresses on chickens, such as disruptions in intestinal flora and inflammation issues within intestines. However, impact an imbalance health during FIM process remains elusive. Therefore, injury, microbiome, metabolome were analyzed individually integrated elucidate process. The findings indicated that fasting resulted notable reduction villus...
Induced molting (IM) can restore the laying rate of aged hens to peak level and rejuvenate ovarian function for second cycle. To explore mechanism remodeling during IM in hens, this study, ninety 71-wk-old lady with 60% uniform weight were selected induction by fasting. Samples (serum fresh tissue) collected on day before fasting (F0), 3rd 16th days (F3, F16), 6th, 15th, 32nd refeeding (R6, R15, R32), number follicles each period was counted. Then, reproductive hormone levels serum...
Currently, the role of long noncoding RNA (lncRNA) DiGeorge syndrome critical region gene 5 (DGCR5) in intervertebral disk degeneration (IDD) remains unclear. This study explored molecular mechanisms how lncRNA DGCR5 promoted human nucleus pulposus cells (NPCs) and pyroptosis during IDD. NPCs were identified by microscopic observation, flow cytometry, immunofluorescence. An vitro NPC model was induced using lipopolysaccharides treatment. SP600125 SB203580 used to inhibit c-Jun N-terminal...
Objective Diabetic liver injury, a chronic complication of diabetes mellitus (DM), has been extensively documented. Dapagliflozin, sodium-glucose co-transporter 2 (SGLT2) inhibitor, shown significant therapeutic benefits in clinical trials for the management However, specific mechanism on treatment diabetic injury with dapagliflozin is not fully understood. Therefore, this study aims to further explore potential based bioinformatics analysis and experimental verification. Methods was induced...
This study evaluated the effects of melatonin on spinal cord injury (SCI)-induced oxidative damage in testes. Adult male C57BL/6 mice were randomly divided into sham-, SCI- or (10 mg/kg, i.p.)-treated SCI groups. To induce SCI, a standard weight-drop method that induced contusion at T10 was used. After 1 week, testicular blood flow velocity measured using Laser Doppler Line Scanner. Malondialdehyde (MDA), glutathione (GSH), oxidised (GSSG) and myeloperoxidase (MPO) testis homogenates....