A5054751430- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Eosinophilic Esophagitis
- Dysphagia Assessment and Management
- COVID-19 and healthcare impacts
- Colorectal Cancer Surgical Treatments
- Helicobacter pylori-related gastroenterology studies
- Appendicitis Diagnosis and Management
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Global Health and Surgery
- Trauma and Emergency Care Studies
- Enhanced Recovery After Surgery
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Tracheal and airway disorders
- Gastrointestinal disorders and treatments
- Palliative Care and End-of-Life Issues
- Radiation Dose and Imaging
- Anorectal Disease Treatments and Outcomes
- Lung Cancer Diagnosis and Treatment
- Artificial Intelligence in Healthcare and Education
Hippocration General Hospital
2016-2025
National and Kapodistrian University of Athens
2016-2025
Swedish Medical Center
2024
University of Milan
2024
IRCCS Policlinico San Donato
2024
University of Pisa
2024
Universiti Sains Malaysia
2024
Metropolitan Hospital
2024
NHS Lothian
2023-2024
Edinburgh Royal Infirmary
2022-2024
A definitive diagnosis of gastroesophageal reflux disease (GERD) depends on endoscopic and/or pH-study criteria. However, high resolution manometry (HRM) can identify factors predicting GERD, such as ineffective esophageal motility (IEM), esophago-gastric junction contractile integral (EGJ-CI), evaluating esophagogastric (EGJ) type and straight leg raise (SLR) maneuver response. We aimed to build externally validate a manometric score (Milan Score) stratify the risk severity in patients...
Boerhaave syndrome is a rare clinical entity associated with high rates of morbidity and mortality. Early recognition the symptoms, identification site extension injury are key in improving prognosis.
Abstract Background Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann’s procedure (HP) for the treatment left-sided emergencies. We aim to evaluate surgical options globally used treat patients with acute emergencies factors that leading choice treatment, comparing HP RPA. Methods This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 who required surgery were included from 204 centers during...
High-resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ) disruption. While type 3 EGJ predicts definitive gastroesophageal reflux disease (GERD), 2 is less clearly implicated in GERD pathogenesis. This study aimed to characterize physiologic findings determine if the HRM-based Milan Score can define within EGJ.
ABSTRACT Introduction According to Lyon 2.0, laryngopharyngeal symptoms (LPS) should undergo upfront pathophysiologic tests. The novel Milan score integrates esophagogastric junction (EGJ) morphology, ineffective esophageal motility, EGJ‐contractile integral (EGJ‐CI), and straight leg raise (SLR) response. It has been demonstrated predict abnormal AET. aim of this study was assess the value in predicting GERD these patients. Methods We prospectively enrolled patients with suspected who...
Objective: To explore the manometric characteristics of patients with severe GERD. assess role HRM features in adjunctive diagnostic Lyon 2.0 criteria and to create a GERD severity prediction model. Summary Background Data: is complex disorder challenges, as symptoms may not reflect disease severity. High-resolution manometry Milan Score numerically quantify degree anti-reflux barrier disruption symptoms. Methods: An international prospective database undergoing pH-impedance (MII-pH) for...
The straight leg raise (SLR) maneuver during high-resolution manometry (HRM) can assess esophagogastric junction (EGJ) barrier function by measuring changes in intraesophageal pressure (IEP) when intra-abdominal is increased. We aimed to determine whether increased esophageal SLR predicts pathologic acid exposure time (AET).Adult patients with persistent gastroesophageal reflux disease (GERD) symptoms undergoing HRM and pH-impedance or wireless pH study off proton pump inhibitor were...
Esophageal cancer (EC) remains one of the most common and aggressive diseases worldwide. This review discusses some debates in modern management disease. Endoscopic procedures for early (T1a-b) are now embedded routine care challenge will be to more accurately select patients endoscopic resection with or without adjuvant therapy. Perioperative multimodal therapies associated improved survival compared surgery alone locally advanced esophageal cancer. However, there is no global consensus on...
An acute respiratory disease caused by the novel coronavirus (SARS-CoV-2), 2019 , has rapidly spread worldwide, necessitating proactive management decisions from clinicians and centers in an effort to mitigate risk of infection.In order focus local resources toward both urgent non-urgent medical treatment overwhelming number infected patients, while supporting safety patients healthcare staff, elective surgeries have largely been postponed or cancelled.While surgical care can be safely...
Current treatment options for achalasia of the esophagus predominantly consist endoscopic myotomy or laparoscopic combined with a partial fundoplication. The intraoperative use conventional manometry has previously been proposed various results. aim present study was to introduce high-resolution (HRM) during surgical and assess long-term outcome this technique.We enrolled patients within time period November 2013 July 2016 who underwent HRM evaluation Eckardt scores (ES) before after...
Mucinous adenocarcinoma associated with an anal fistula is a rare oncologic entity which may pose diagnostic and therapeutic challenges for Surgeons Medical Oncologists. Few reported cases without definite guidelines exist. It represents 2-3% of all gastrointestinal malignancies arises from chronic fistulas, ischiorectal or perianal abscesses. We report case mucinous in 65-year-old male initially surgically treated multiple times recurrent ano 5 years duration. He presented fistula....
Achalasia is a primary oesophageal motility disorder. Although aetiology remains mainly unknown, genetic risk variant, rs28688207 in HLA-DQB1, showed strong achalasia association suggesting involvement of immune-mediated processes the pathogenesis. High-resolution manometry recognises three types achalasia. The aim our study was to perform first genotype-phenotype analysis investigating frequency across high-resolution subtypes.
The non-recurrent laryngeal nerve (nRLN) is a rare anatomic variation that every head and neck surgeon must be aware of, in order to avoid intraoperative injury which leads postoperative morbidity. We are reporting case of nRLN 47 year old female patient with medullary thyroid carcinoma who was surgically treated total thyroidectomy lymph node dissection. Both two inferior nerves were identified, fully exposed preserved along their cervical courses. However, we found the right directly...