A5083956804- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Tracheal and airway disorders
- Gastroesophageal reflux and treatments
- Colorectal Cancer Screening and Detection
- Voice and Speech Disorders
- Agricultural pest management studies
- Insect-Plant Interactions and Control
- Eosinophilic Esophagitis
- Insect Pest Control Strategies
- Child Nutrition and Feeding Issues
- Gastrointestinal motility and disorders
- Cannabis and Cannabinoid Research
- Agricultural Practices and Plant Genetics
- Insect Resistance and Genetics
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal disorders and treatments
- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Healthcare Policy and Management
- Cardiac Arrhythmias and Treatments
The Ohio State University
2018-2023
The Ohio State University Wexner Medical Center
2017-2023
Tamil Nadu Agricultural University
2021
RELX Group (Netherlands)
2020
Medical College of Wisconsin
2016-2018
Jawaharlal Institute of Post Graduate Medical Education and Research
2017
University of Kansas
2015
Rosalind Franklin University of Medicine and Science
2011-2014
Madras Medical College
2014
Franklin University
2014
Chronic gastroesophageal reflux disease (GERD) is a risk factor for Barrett's esophagus (BE), the most important surrogate marker development of esophageal adenocarcinoma (EAC). The need to document presence intestinal metaplasia in biopsies from columnar lined (CLE) diagnose BE debated. objective this study was prospectively evaluate prevalence and factors CLE large cohort GERD patients undergoing upper endoscopy.Consecutive presenting endoscopy unit at tertiary referral center their index...
Background. There is a wide disparity in the use of automated peritoneal dialysis (APD) or continuous ambulatory (CAPD) UK. This may be due to perceived quality life and technique survival advantage with APD, although evidence lacking.
Abstract Background Recent studies have shown high prevalence of oropharyngeal dysphagia associated with frailty‐ and age‐related muscle weakness. Strength training exercises been advocated for locomotive health maintenance in the elderly positive outcomes. As muscles involved phase swallowing are also comprised striated muscles, aim this study was to determine biomechanical effect a novel resistance exercise program, Swallowing Against Laryngeal Restriction ( SALR ), on pharyngeal healthy...
The straight leg raise (SLR) maneuver during high-resolution manometry (HRM) can assess esophagogastric junction (EGJ) barrier function by measuring changes in intraesophageal pressure (IEP) when intra-abdominal is increased. We aimed to determine whether increased esophageal SLR predicts pathologic acid exposure time (AET).Adult patients with persistent gastroesophageal reflux disease (GERD) symptoms undergoing HRM and pH-impedance or wireless pH study off proton pump inhibitor were...
To date, rehabilitative exercises aimed at strengthening the pharyngeal muscles have not been developed due to inability successfully overload and fatigue these during their contraction, a necessary requirement for strength training. The purpose of this study was test hypothesis that applying resistance against anterosuperior movement hyolaryngeal complex will by repetitive swallowing result in manifested reduction peristaltic amplitude. Studies were done two groups. In group 1 studies 15...
The goal of this study was to evaluate the influence defecation postural modification devices (DPMDs) on normal bowel patterns.The introduction DPMDs has brought increased awareness habits in western populations.A prospective crossover volunteers performed that included real-time collection data regarding movements (BMs) for 4 weeks (first 2 wk without DPMD and subsequent with DPMD). Primary outcomes interest BM duration, straining, emptiness use.In total, 52 participants (mean age, 29 y...
<b>Background and study aim:</b> Data are limited on the natural history of patients with Barrett's esophagus a diagnosis "indefinite for dysplasia" (IND). The aims this were to: (i) determine rates progression to high grade dysplasia (HGD) or esophageal adenocarcinoma, compare these low (LGD); (ii) proportion whose histological IND changed follow-up endoscopy. <b>Patients methods:</b> Demographic, endoscopic, histologic information diagnoses LGD at least 12 months extracted from database...
Abstract Background Recent technological advances incorporated in high resolution manometry have justifiably heightened interest manometric evaluation of the pharynx. Despite this interest, from both physiologic and clinical perspective there remain a number unanswered questions regarding magnitude variability pharyngeal pressure phenomena. Therefore, aim present study was to characterize healthy individuals inter‐subject recording‐site specific peristaltic Methods We studied 32 subjects...
Cigarette smoking has been associated with an increased risk of oesophageal adenocarcinoma (OAC). However, the impact and more importantly cessation on Barrett's oesophagus (BO) is unclear.The aim study to evaluate association between cigarette presence BO in a large prospective cohort patients gastro-oesophageal reflux disease (GORD).Patients presenting endoscopy unit for upper completed validated GORD questionnaire information demographics (age, gender, ethnicity), [status (current/past),...
The electrocardiographic parameters QRS duration, QRS-T angle and QTc can predict mortality in patients with cardiovascular disease. prgnostic value of these hospitalized syncope needs investigation.We retrospectively studied 590 consecutive syncope. After excluding baseline abnormal rhythm, QT- prolonging medications, missing data, 459 were analyzed. Baseline demographic characteristics, co-morbidities, medication use, San Francisco Syncope Rule (SFSR) Osservatorio Epidemiologico sulla...
Abstract In recent years, the legalization and social acceptability of cannabis use have increased in United States. Concurrently, prevalence has continued to rise, products diversified. There are growing concerns regarding health effects regular high‐potency use, new research shed light on its potentially negative effects. Here, we review evidence gastrointestinal (GI) cannabinoids. Dysregulation endocannabinoid system might contribute various GI disorders, including irritable bowel...
The present understanding of pharyngeal motor function remains incomplete. Among the remaining gaps knowledge in this regard is magnitude variability peristaltic pressure amplitude. Although can pose difficulty interpretation manometric findings, its inform operational range and reserve contractile function. We aimed to define intra- intersubject intersession select parameters and, using information, determine number swallow repetitions for acquiring reliable data. recorded peristalsis 10...
Paraganglioma are tumours arising from neural crest cells of the sympathetic and parasympathetic paraganglia. Functional paraganglioma presents with symptoms catecholamine excess that includes hypertension, flushing, diaphoresis, etc. Non-functional usually found incidentally during imaging studies. Early diagnoses functional important because their removal is often curative. We present case a young man who presented hypertensive crisis severe headache, was later to have paraganglioma.
Amitriptyline (AT) is recommended as first-line prophylactic therapy in patients with cyclic vomiting syndrome (CVS). However, significant side effects limit its use and dosing based on trial error. Though the Clinical Pharmacogenetic Implementation Consortium (CPIC) Guidelines recommend for AT CY2D6 CYP2C19 genotype profile, this not followed clinical practice.This pilot study determined CYP2D6 genotypes ascertained association adverse drug reactions (ADRs), response, serum concentration of...
Erdheim-Chester disease (ECD) is a rare form of systemic histiocytosis, typically presenting with striking osseous involvement characterized by bilateral osteosclerosis and organs such as the lung, pituitary gland, heart, brain. Liver ECD extremely uncommon. We report 56-year-old woman newly diagnosed cirrhosis signs concerning for intra-abdominal malignancy, including omental caking peritoneal thickening. biopsy demonstrated xanthogranulomatous infiltration from ECD. The patient showed...
A 40-year-old woman presented with postprandial abdominal pain in the epigastric region for 4 days. In past 6 months, she had intermittent spite of 6 weeks proton pump therapy and weight loss 10 kg. She denied any history melena, haematochezia, fever, jaundice, vomiting or diarrhoea. Her physical examination was unremarkable. Laboratory studies revealed mild leucocytosis (11 540/mm3 …