- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Spine and Intervertebral Disc Pathology
- Prostate Cancer Diagnosis and Treatment
- Urinary Tract Infections Management
- Prostate Cancer Treatment and Research
- Parathyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Urinary Bladder and Prostate Research
- Kidney Stones and Urolithiasis Treatments
- Renal and Vascular Pathologies
- Musculoskeletal pain and rehabilitation
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Adrenal and Paraganglionic Tumors
- Acute Kidney Injury Research
- Diverticular Disease and Complications
- Renal and related cancers
- Social and Educational Sciences
- Radiation Dose and Imaging
- Medical Imaging and Analysis
- Aortic aneurysm repair treatments
- MRI in cancer diagnosis
Karolinska University Hospital
2007-2025
Sahlgrenska University Hospital
2015-2024
Region Västra Götaland
2019-2024
University of Gothenburg
2015-2024
University of New Brunswick
2018
Institute of Economic Research of the Slovak Academy of Sciences
2012
Aalto University
2012
University of Alberta
2012
University of Helsinki
2012
Södertörn University
2012
Retrospective studies have found that patients receiving general anesthesia for endovascular treatment in acute ischemic stroke worse neurological outcome compared with conscious sedation. In this prospective randomized single-center study, we investigated the impact of technique on patients.Ninety 2013 to 2016 were included and or Difference at 3 months, measured as modified Rankin Scale score, was analyzed (primary outcome) early improvement National Institutes Health Stroke cerebral...
Comprehensive characterization of the adipose tissue in women with polycystic ovary syndrome (PCOS), over a wide range body mass indices (BMIs), is lacking. Mechanisms behind insulin resistance PCOS are unclear. To characterize and controls matched pair-wise for age BMI, to identify factors, among characteristics serum sex steroids, that associated sensitivity PCOS. Seventy-four 31 were included. BMI was 18–47 (PCOS) 19–41 kg/m2 (controls). Anthropometric variables, volumes...
Screening for prostate cancer is burdened by a high rate of overdiagnosis. The most appropriate algorithm population-based screening unknown.
Data on the efficacy and safety of screening for prostate cancer with magnetic resonance imaging (MRI) are needed from studies follow-up screening.
The thoracolumbar spine was examined by magnetic resonance imaging (MRI) and the history of back pain analyzed in 24 male elite gymnasts (age range, 19–29 years) 16 nonathietes 23–36 years). Disc degeneration, defined as reduced disc signal intensity, significantly more common athletes (75%) than nonathletes (31%). also had a higher incidence other abnormalities spine, there significant correlation between intensity among gymnasts. There were correlations abnormal vertebral configuration...
Back pain and radiological changes of the thoracolumbar spine were investigated in 142 top athletes, representing wrestling, gymnastics, soccer tennis (age range 14-25 years). All groups athletes reported back at high frequencies (50-85%). Male gymnasts had significantly increased incidence severity as compared to rest athletes. Radiological abnormalities occurred 36-55% Reduced disc height, Schmorl's nodes change configuration vertebral bodies correlated with (P<0.05, P<0.01 P<0.05):...
To prospectively evaluate, by means of self-assessed questionnaires, patient acceptance computed tomographic (CT) colonography compared with that conventional colonoscopy, when performed in patients or suspected having colorectal disease.One hundred eleven underwent CT followed immediately colonoscopy. Patient was evaluated and the proportions who favored one examination were compared. The main variables overall impression, discomfort during air filling instrumentation, perceived pain, using...
To update quality standards for CT colonography based on consensus among opinion leaders within the European Society of Gastrointestinal and Abdominal Radiology (ESGAR).A multinational panel nine members ESGAR Working Group (representing six EU countries) used a modified Delphi process to rate their level agreement variety statements pertaining acquisition, interpretation implementation colonography. Four rounds were conducted, each at 2 months interval.The elaborated 86 statements. In final...
Magnetic resonance imaging(MRI) and targeted biopsies reduce overdiagnosis of prostate cancer(PC). It is uncertain how this strategy performs for low PSA levels. The objective was to investigate the PI-RADS distribution, frequency characteristics screen-detected PC with 1.8-<3ng/ml 3-<10ng/ml.
From 1996 to 1999, back pain and radiological changes in the thoraco‐lumbar spine were investigated 134 former top athletes, representing wrestling, gymnastics, soccer tennis (age 27–39 years) a group of 28 non‐athletes comparable age. This is long‐term follow‐up investigation previous study with clinical correlation. Despite significantly more abnormalities among they did not report higher frequency than non‐athletes. A decrease disc height or new reduction one intervertebral discs between...
A radiologic study of the thoraco-lumbar spine was performed in 143 (117 male and 26 female) athletes (wrestlers, gymnasts, soccer players tennis players), aged 14 to 25 years 30 non-athletes, 19 years. Film interpretation made after mixing films from all groups without knowledge individual's identity. Various types abnormalities occurred both non-athletes but were more common among athletes, especially gymnasts wrestlers. Abnormalities vertebral ring apophysis exclusively athletes....
The objective of our study was to prospectively determine the frequency and clinical importance extracolonic findings on CT colonography in symptomatic patients. SUBJECTS AND METHODS. One hundred eleven patients referred for colonoscopy underwent before colonoscopy. Helical from diaphragm symphysis performed with patient supine prone positions after rectal air insufflation. Image interpretation done a digital workstation. Extracolonic were classified as minor, moderate, or major according...
Virulence-associated properties of 606 urinary isolates from 174 children with tract infections were related to severity infection and factors increasing host susceptibility, e.g., vesicoureteral reflux (grade II or higher) P1 blood group phenotype. A high proportion strains Escherichia coli causing first recurrent episodes acute pyelonephritis in without expressed the previously noted frequency certain 0 antigens, resistance serum killing, hemolysin production, adhesive capacity....
ESGE European Society of Gastrointestinal Endoscopy FIT fecal immunochemical test FOBT occult blood testing GRADE Grading Recommendations Assessment, Development and Evaluation NPV negative predictive value PEG polyethylene glycol PPV positive This is an official guideline the (ESGE) Abdominal Radiology (ESGAR), published in simultaneously.It addresses clinical indications for use computed tomographic colonography (CTC).A targeted literature search was performed to evaluate evidence...
Mild primary hyperparathyroidism (PHPT) is a common disease especially in middle-aged and elderly women. The diagnosis frequently made incidentally treatment strategies are widely discussed. To study the effect of parathyroidectomy (PTX) compared with observation (OBS) on biochemistry, safety, bone mineral density (BMD), new fractures. Prospective, randomized controlled (SIPH study), 5-year follow-up. was conducted at multicenter, tertiary referral centers. Of 191 patients mild PHPT,...
Mild primary hyperparathyroidism (PHPT) is known to affect the skeleton, even though patients usually are asymptomatic. Treatment strategies have been widely discussed. However, long-term randomized studies comparing parathyroidectomy observation lacking. The objective was study effect of (PTX) compared with (OBS) on bone mineral density (BMD) in g/cm2 and T-scores biochemical markers turnover (P1NP CTX-1) a prospective controlled mild PHPT after 5 years follow-up. Of 191 either PTX or OBS,...
Primary hyperparathyroidism (PHPT) is a common endocrine disorder associated with increased risk for fractures, cardiovascular disease, kidney and cancer mortality. In mild PHPT modest hypercalcemia without known morbidities, parathyroidectomy (PTX) debated because no long-term randomized trials have been performed.To examine the effect of PTX on regard to mortality (primary end point) key morbidities (secondary point).Prospective controlled trial. (ClinicalTrials.gov: NCT00522028).Eight...
We investigated whether adding 4Kscore as a reflex test to prostate-specific antigen (PSA) could improve the screening algorithm for prostate cancer (PC).
During a 2 year period, 175 children below 6 years of age (median 0.4 year) with non‐obstructive symptomatic urinary tract infection were studied by 99m Tc dimercaptosuccinic acid (DMSA) scintigraphy. DMSA scintigraphy was performed at median 10 days after the start treatment and abnormal in 73 (42%), equivocal 29 (16%) normal (42%). Reflux seen 27% all 38% renal units that A decreasing frequency abnormalities within first 14 treatment. C‐reactive protein grade reflux correlated...
Purpose: To suggest a more precise tool when assessing the risk of contrast-medium-induced nephropathy (CIN), i.e. ratio between contrast medium (CM) dose expressed in grams iodine (g-I) and estimated glomerular filtration rate ml/min (eGFR; based on equations using serum-creatinine (s-Cr), weight, height, age, and/or sex), here named I-dose/GFR ratio. Material Methods: A Medline search published CIN investigations reporting mean eGFR low-osmolality CM (LOCM) identified 10 randomized...
Urine and serum interleukin (IL)-6 IL-8responseswere higher in children with febrile urinary tract infection (n = 61) than those asymptomatic bacteriuria 39). By univariate analysis, cytokine levels were related to age, sex, reflux, renal scarring, urine leukocytes, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), bacterial properties (P fimbriae but not hemolysin). Multivariate modeling showed that IL-6 responseswere girls boys, increased positively associated CRP, ESR, IL-6,...