A5103080211- Traditional Chinese Medicine Analysis
- Cancer-related molecular mechanisms research
- Long-Term Effects of COVID-19
- Neurogenesis and neuroplasticity mechanisms
- Bacterial Identification and Susceptibility Testing
- Caveolin-1 and cellular processes
- Lymphoma Diagnosis and Treatment
- Trace Elements in Health
- Neurological Disease Mechanisms and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- COVID-19 and Mental Health
- Digestive system and related health
- Peroxisome Proliferator-Activated Receptors
- Gastrointestinal Tumor Research and Treatment
- Lipid metabolism and disorders
- Diabetes and associated disorders
- COVID-19 Clinical Research Studies
- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Neurological diseases and metabolism
- Chronic Lymphocytic Leukemia Research
- HIV-related health complications and treatments
- Renin-Angiotensin System Studies
- Cancer Cells and Metastasis
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2023-2024
Hunan Academy of Traditional Chinese Medicine
2023-2024
Hunan Normal University
2024
Yueyang Hospital
2024
Shanghai University of Traditional Chinese Medicine
2024
Hunan University of Traditional Chinese Medicine
2019-2023
Chung-Ang University
2023
Chung-Ang University Hospital
2023
Soochow University
2020
Wuxi Ninth People's Hospital
2020
Since the first outbreak of coronavirus disease 2019 (COVID-19) occurred in December 2019, more than 51 million cases had been reported globally. We aimed to identify risk factors for in-hospital fatal outcome and severe pneumonia this disease. This is a retrospective, multicentre study, which included all confirmed COVID-19 with definite outcomes (died or discharged) hospitalized between 1 January 4 March 2020 Wuhan. Of 665 patients included, 70 died 595 discharged (including 333 mild 262...
The expression of cancer stem cell (CSC) markers adversely affect the survival prognosis patients with hepatocellular carcinoma (HCC), but it is not clear which marker has best predictive effect on and diagnostic value indicators HCC. Therefore, present study performed a network meta-analysis to compare prognostic expressions several CSC for HCC identify most efficient marker. Studies associations positive overall (OS) rate, disease-free (DFS) recurrence-free (RFS) recurrence...
Folate metabolism makes a crucial contribution towards late-onset Alzheimer's disease (LOAD). Moreover, methylenetetrahydrofolate reductase (MTHFR) constitutes the primary enzyme of folate pathway. We hypothesize that there is an association C677T polymorphism in MTHFR gene with susceptibility to LOAD. Previous published research has investigated link between polymorphisms and LOAD susceptibility; nevertheless, findings have continued be not only controversial, but also indecisive....
Background: Since first outbreak of coronavirus disease 2019 (COVID-19) occurred in December 2019, more than one million cases had been reported globally. We aimed to identify the risk factors for in-hospital fatal outcome and severe illness this disease.Methods: This is a retrospective, multicentre study, which included all confirmed COVID-19 with definite outcomes (died or discharged) hospitalized between January 1st March 4th 2020 Wuhan. Findings: Of 665 patients included, 70 died, 595...
Background: Promoting the recovery of cerebral blood circulation after infarction (CI) is an important intervention. Buyang Huanwu decoction (BHD) a classic prescription for treating CI, with pharmacological effect promoting angiogenesis. Glycolysis, as energy supply method in focal area affects angiogenesis.Purpose: This study aimed to explore BHD on angiogenesis regulating glycolysis CI.Methods: According 22 effective active ingredients identified by our research team, network pharmacology...
The long-term outcomes of PCNSL remains poor which is partially explained by that more than half patients are diagnosed over the age 65 years. optimal treatment strategy for newly has not been established, especially in elderly. While backbone young consist high-dose methotrexate (MTX) and cytarabine, their feasibility widely tested Moreover, addition rituximab demonstrated inconsistent findings. We have carried out a phase II study to evaluate efficacy safety plus MTX followed cytarabine...
Introduction: Previous studies have shown that combination of acalabrutinib with rituximab and lenalidomide has a synergistic effect in killing NHL cells. We hypothesized the R2A regimen would show satisfying efficacy for relapsed/refractory B cell tolerable toxicity profile. Methods: In this single-arm, phase 2, multicenter study Republic Korea, 66 patients (median age 67.5, range 20–87) were included. Patients who diagnosed mantle lymphoma excluded. The received regimen, cycle which...