A5106121518- Pharmaceutical Practices and Patient Outcomes
- Antibiotic Use and Resistance
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Patient Satisfaction in Healthcare
- Heart Failure Treatment and Management
- Clostridium difficile and Clostridium perfringens research
- Patient Safety and Medication Errors
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Pharmaceutical studies and practices
- Emergency and Acute Care Studies
- Microscopic Colitis
- Cardiac, Anesthesia and Surgical Outcomes
- Infection Control in Healthcare
- Pharmaceutical Economics and Policy
- Urinary Tract Infections Management
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Atrial Fibrillation Management and Outcomes
- Analytical Chemistry and Chromatography
- Cultural Industries and Urban Development
- Analytical Methods in Pharmaceuticals
- Anesthesia and Sedative Agents
Northern Health and Social Care Trust
2015-2024
Antrim Area Hospital
2011-2024
St Michaels Hospital
2024
Conestoga College
2024
Unity Health Toronto
2024
St. Michael's Hospital
2023-2024
Business Innovation Centre
2024
University of Toronto
2017-2024
Royal Hospital for Children
2024
University of Aberdeen
2024
Abstract Rationale, aims and objectives To determine whether an increased input by clinical pharmacists at each stage of the patient’s hospital journey, from admission through discharge, resulted in enhanced level patient care as measured a number economic outcomes. Methods This project was designed to address medicines management issues patients deemed risk drug‐related problems. During project, these latter time were randomly assigned integrated (IMM) service group ( n = 371) or regular...
To evaluate the impact of a high-risk antibiotic stewardship programme on reducing use and hospital Clostridium difficile infection (CDI) incidence rates. A secondary objective was to present possible utility time-series analysis as an risk classification tool. This interventional, retrospective, ecological investigation in medium-sized over 6.5 years (January 2004 June 2010). The intervention restriction antibiotics (second-generation cephalosporins, third-generation fluoroquinolones...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen worldwide. A wide range of factors have been suggested to influence the spread MRSA. The objective this study was evaluate effect antimicrobial drug use and infection control practices on MRSA incidence in 426-bed general teaching hospital Northern Ireland.The present research involved retrospective collection monthly data usage antibiotics within over 5 year period (January 2000-December 2004). multivariate...
Clinical pharmacy as an area of practice, education and research started developing around the 1960s when pharmacists across globe gradually identified need to focus more on ensuring appropriate use medicines improve patient outcomes rather than being engaged in manufacturing supply. Since that time numerous studies have shown positive impact clinical services (CPS). The for wider adoption CPS worldwide becomes urgent, global population ages, prevalence polypharmacy well shortage healthcare...
• The emergence and spread of bacteria producing extended-spectrum beta-lactamases (ESBLs) has important therapeutic epidemiologic implications. A key target for the establishment hospital antibiotic stewardship is reducing occurrence additional resistance. Further research needed to accumulate supporting evidence that use will result in a parallel reduction resistance.• Fluoroquinolone restriction reversed ciprofloxacin resistance primary secondary healthcare settings. reduced...
Aims Inappropriate use of antibiotics is one the most important factors contributing to emergence drug resistant pathogens. The purpose this study was measure clinical impact antimicrobial stewardship programme (ASP) interventions on hospitalized patients at Intensive care unit Palestinian Medical Complex. Methods A prospective audit with intervention and feedback by ASP team within 48–72 h antibiotic administration began in September 2015. Four months pre‐ASP data were compared 4 post‐ASP...
This paper explores the role of religion in formation and development enterprise culture. The approach is that legitimisation leading to an increase environmental munificence. It argued entrepreneurial activity was encouraged by use theology specifically articulated Margaret Thatcher. Parallels are drawn Max Weber’s work on Protestant ethic, particularly way he changes socio‐cultural framework allowed, permitted action what called new rational capitalism. Different aspects theological...
Aims Helicobacter pylori ( H. ) eradication rate varies according to the treatment regimen used and other factors, e.g. antimicrobial resistance patient compliance. The aim of present study was evaluate influence counselling follow‐up on rates document effectiveness a 1 week consisting lansoprazole (30 mg once daily), amoxicillin (1 g twice daily) clarithromycin (500 daily). Methods Seventy‐six dyspeptic patients, who at endoscopy were found have gastritis, duodenitis or ulceration, positive...
The aim of the present study was to evaluate incidence, risk factors and cost implications Clostridium difficile-associated diarrhoea (CDAD) in hospitalized adult patients.Eighty-seven patients, positively identified as having CDAD, were reviewed retrospectively determine CDAD.The clinical manifestations, addition diarrhoea, included elevated temperature (= 37.8 degrees C; 42.5%), abdominal pain (63. 2%) leucocytosis (=12 x 109 cells/l; 52.9%). Eight patients underwent endoscopy,...
To report a large outbreak of Clostridium difficile infection (CDI; ribotype 027) between June 2007 and August 2008, describe control measures, evaluate the impact restricting use fluoroquinolones in controlling outbreak.Outbreak investigation 3 acute care hospitals Northern Health Social Care Trust Ireland.Implementation series CDI measures that targeted high-risk antibiotic agents (ie, restriction fluoroquinolones), practices, environmental hygiene.A total 318 cases were identified during...
Aims To implement pharmacist‐led, postdischarge telephone follow‐up (TFU) intervention and to evaluate its impact on rehospitalization parameters in polypharmacy patients, via comparison with a well‐matched control group. Method Pragmatic, prospective, quasi‐experimental study. Intervention patients were matched by propensity score techniques Guided results from pilot study, clinical pharmacists implemented TFU intervention, added routine integrated medicines management service. Results...
ABSTRACT The objective of this study was to evaluate the effects antimicrobial drug use, gastric acid-suppressive agent and infection control practices on incidence Clostridium difficile -associated diarrhea (CDAD) in a 426-bed general teaching hospital Northern Ireland. retrospective ecological design. A multivariate autoregressive integrated moving average (time-series analysis) model built relate CDAD with antibiotic within over 5-year period (February 2002 March 2007). findings showed...
The aim of the study was to assess current patterns antibiotic prescribing and impact a hospital policy on these practices.The involved collecting information regarding hospitalized patients utilizing ESAC audit tool.In site hospital, use restricted agents low whilst non-restricted high. Compliance with guidelines 70%.The findings identified monitoring antibiotics compliance as targets for quality improvements in our hospital. Point prevalence surveys may offer simple method policies, thus,...
To assess antimicrobial prescribing in a Northern Ireland hospital (Antrim Area Hospital (AAH)) and compare them with those of Jordan (Specialty Hospital). Using the Global-PPS approach, present study surveyed patients admitted to 2015, prescribed antibiotics, set quality control indicators related antibiotics. Ultimately, 444 112 inpatients AAH Specialty Hospital, respectively, were surveyed. For medical group, 165 239 antibiotics AAH, while 44 65 In relation surgical 34 treated for...
To evaluate the impact of COVID-19 pandemic on patterns antimicrobial use and incidence pathogens in primary secondary healthcare settings Northern Ireland.Data were collected antibiotic Gram-positive Gram-negative from Ireland for period before (January 2015-March 2020) during (April 2020-December 2021) pandemic. Time series intervention analysis methods utilized.In hospital setting, mean total consumption was 1864.5 defined daily doses (DDDs) per 1000 occupied-bed days (OBD), showing no...
Sub-optimal medicines use is a challenge globally, contributing to poorer health outcomes, inefficiencies and waste. The Medicines Optimisation Innovation Centre (MOIC) was established in Northern Ireland by the Department of Health (DH) 2015 support implementation Quality Framework.
The effects of an integrated medicines management (IMM) program on medication appropriateness are discussed.Patients enrolled in IMM project within a hospital were randomly allocated to either control or intervention group. Patients the group received standard pharmaceutical care, while patients service. medications prescribed was estimated admission and discharge using Medicines Appropriateness Index (MAI), which ranged from 0 (no prescribing problems) 18 (most problems). For each scored,...
Abstract Rationale, aims and objectives Previous service development work in the area of integrated medicines management (IMM) has demonstrated clear quality improvements a targeted group patients within hospital Northern Ireland. In order to determine whether this programme could be transferable routine practice thereby assess its generalizability, research been carried out quantify health care benefits incorporating concept IMM as clinical practice. Method The was delivered all eligible...