- Cancer Immunotherapy and Biomarkers
- Immune cells in cancer
- Biomarkers in Disease Mechanisms
- COVID-19 and healthcare impacts
- Cancer, Hypoxia, and Metabolism
- Long-Term Effects of COVID-19
- Antimicrobial Peptides and Activities
- Nutrition and Health in Aging
- Respiratory viral infections research
- Intensive Care Unit Cognitive Disorders
- Cardiac Imaging and Diagnostics
- Sirtuins and Resveratrol in Medicine
- Adenosine and Purinergic Signaling
- Cancer Genomics and Diagnostics
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuropeptides and Animal Physiology
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Salivary Gland Disorders and Functions
- Renal cell carcinoma treatment
- Calcium signaling and nucleotide metabolism
- SARS-CoV-2 and COVID-19 Research
IRCCS Humanitas Research Hospital
2022-2024
Humanitas University
2023-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2020-2023
University of Plymouth
2019
The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of health care systems during highest viral diffusion rate. Patients reaching emergency department had to be either hospitalized (inpatients) or discharged (outpatients). Still, decision was taken based on individual assessment actual clinical condition, without specific biomarkers predict future improvement deterioration, and patients often returned hospital for aggravation their condition. Here, we have developed a new combined...
Background and Aims The risk of disease progression in MASH increases proportionally to the pathological stage fibrosis. This latter is evaluated through a semi-quantitative process, which has limited sensitivity reflecting changes or response treatment. study aims test clinical impact Artificial Intelligence (AI) characterizing liver fibrosis patients. Methods included 60 patients with diagnosis MASH. Among these, 17 received medical treatment underwent post-treatment biopsy. For each...
Macrophages (Mϕs) play a central role in mucosal immunity by pathogen sensing and instruction of adaptive immune responses. Prior challenge to endotoxin can render Mφs refractory secondary exposure, suppressing the inflammatory response. Previous studies demonstrated differential subset-specific sensitivity tolerance (ET), mediated LPS from oral pathogen, Porphyromonas gingivalis (PG). The aim this study was investigate ET mechanisms associated with Mφ subsets responding entropathogenic E....
Even though cancer patients are generally considered more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the mechanisms driving their predisposition forms of disease 2019 (COVID-19) have not yet been deciphered. Since metabolic disorders associated with homeostatic frailty, which increases risk infection and cancer, we asked whether could identify immunometabolic pathways intersecting SARS-CoV-2 infection. Thanks a combined flow cytometry multiomics...