A5064044182- Glioma Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Infectious Diseases and Tuberculosis
- Cerebral Venous Sinus Thrombosis
- Spine and Intervertebral Disc Pathology
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- Neurofibromatosis and Schwannoma Cases
- Intracerebral and Subarachnoid Hemorrhage Research
- Musculoskeletal pain and rehabilitation
- Head and Neck Surgical Oncology
- Neurological Complications and Syndromes
- Management of metastatic bone disease
- Infectious Encephalopathies and Encephalitis
- MRI in cancer diagnosis
- Medical Imaging Techniques and Applications
- Surgical Simulation and Training
- Intracranial Aneurysms: Treatment and Complications
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Functional Brain Connectivity Studies
Ottawa Hospital
2016-2025
University of Ottawa
2016-2025
Ottawa Hospital Research Institute
2014-2024
uOttawa Brain and Mind Research Institute
2023-2024
MIND Research Institute
2023
Deleted Institution
2023
Purdue University West Lafayette
2022
St. Michael's Hospital
2021
Foothills Medical Centre
2021
University of Calgary
2021
Abstract In 51 (1.2%) of 4,250 patients studied by selective coronary arteriography, one or more major elements the arterial system originated from sinuses Valsalva in an ectopic manner. The majority variations involved left artery. ostia were located right sinus Valsalva. Failure to recognize origin can prolong arteriography procedures and lead errors interpretation artery anatomy pathology. It is concluded this experience that incidence location are relatively predictable. data useful...
Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification obtained in 32 patients. Tumor initially confined to nerve recurred one five after complete resection. The actuarial survival 25 irradiated biopsy-proven chiasm 96%, 90%, 90% at 5, 10, 15 years, respectively, progression-free 87% Vision stabilized or improved 86% radiotherapy. Patients a dose greater than NSD 1385 ret had...
Spine-related disorders are a leading cause of global disability and burden on society to public health. Currently, there is no comprehensive, evidence-based model care for spine-related disorders, which includes back neck pain, deformity, spine injury, neurological conditions, spinal diseases, pathology, that could be applied in health settings. The purposes this paper propose: (1) principles transform the delivery care; (2) an globally; (3) implementation suggestions. Global Spine Care...
The purpose of this report is to describe the development an evidence-based care pathway that can be implemented globally. Global Spine Care Initiative (GSCI) team extracted interventions recommended for management spinal disorders from six GSCI articles synthesized available evidence guidelines and relevant literature. Sixty-eight international interprofessional clinicians scientists with expertise in spine-related conditions were invited participate. An iterative consensus process was...
<h3>BACKGROUND AND PURPOSE:</h3> Dynamic contrast-enhanced MR imaging parameters can be biased by poor measurement of the vascular input function. We have compared diagnostic accuracy dynamic using a phase-derived function and "bookend" T1 measurements with DSC for preoperative grading astrocytomas. <h3>MATERIALS METHODS:</h3> This prospective study included 48 patients new pathologic diagnosis an astrocytoma. Preoperative was performed at 3T, which 2 injections 5-mL gadobutrol imaging....
Background The appearance of a new enhancing lesion after surgery and chemoradiation for high‐grade glioma (HGG) presents common diagnostic dilemma. Histopathological analysis remains the reference standard in this situation. Purpose To prospectively compare accuracy dynamic contrast‐enhanced (DCE) vs. susceptibility contrast (DSC) differentiating tumor recurrence (TR) from radiation necrosis (RN). Study Type Prospective study. Population In all, 98 consecutive treated HGG patients with...
<h3>BACKGROUND AND PURPOSE:</h3> Centrally restricted diffusion has been demonstrated in recurrent high-grade gliomas treated with bevacizumab. Our purpose was to assess the accuracy of centrally diagnosis radiation necrosis not <h3>MATERIALS METHODS:</h3> In this prospective study, we enrolled patients who developed a new ring-enhancing necrotic lesion and underwent re-resection. The presence within assessed visually on trace images by ADC measurements 3T preoperative tensor examination....
Tuberculosis (TB) has shown a resurgence in nonendemic populations recent years and accounts for 8 million deaths annually the world. Central nervous system involvement is one of most serious forms this infection, acting as prominent cause morbidity mortality developing countries. The rising number cases developed countries mostly attributed to factors such pandemic acquired immunodeficiency syndrome increased migration globalized Mycobacterium TB responsible almost all tubercular infection...
The purpose of this report is to describe the development a classification system that would apply anyone with spine-related concern and can be used in an evidence-based spine care pathway. Existing systems for spinal disorders were assembled. A seed document was developed through round-table discussions followed by modified Delphi process. International interprofessional clinicians scientists expertise conditions invited participate. Thirty-six experts from 15 countries participated. After...
Background Carotid free-floating thrombi (FFT) in patients with acute transient ischaemic attack (TIA)/stroke have a high risk of early recurrent stroke. Management depends on aetiology, which can include local plaque rupture, dissection, coagulopathy, malignancy and cardioembolism. Our objectives were to classify the underlying aetiology FFT estimate proportion stenosis requiring revascularisation. Methods We prospectively enrolled consecutive presenting three comprehensive stroke centres...
Background Edited MRS technique such as MEshcher‐GArwood Point RESolved Spectroscopy (MEGA‐PRESS) can determine isocitrate dehydrogenase mutation (IDH) status in patients with gliomas but its accuracy assessing glioma grade has not yet been formally evaluated. Purpose To evaluate the diagnostic of metabolites lactate obtained from PRESS and MEGA‐PRESS sequences preoperative grading glioma. assess prognostic value those metabolite ratios overall survival gliomas. Study Type Prospective....
History A 30-year-old female patient who was 25 weeks pregnant presented to the emergency department with a 1-month history of mild headache and 2 progressive somnolence photophobia accompanied by binocular horizontal diplopia right gaze deviation. The also described new neck pain passive head movements, without stiffness. Overall, pregnancy uncomplicated, no high-risk features. Fever, chills, cough, shortness breath, abdominal or chest were denied. had rash, intravenous drug use,...
<h3>BACKGROUND AND PURPOSE:</h3> The accuracy of tumor plasma volume and <i>K</i><sup>trans</sup> estimates obtained with DCE MR imaging may have inaccuracies introduced by a poor estimation the VIF. In this study, we evaluated diagnostic novel technique using phase-derived VIF “bookend” T1 measurements in preoperative grading patients suspected gliomas. <h3>MATERIALS METHODS:</h3> This prospective study included 46 new pathologically confirmed diagnosis glioma. Both magnitude phase images...
Patients presenting with visual disturbances often require a neuroimaging approach. The spectrum of includes three main categories: vision impairment, ocular motility dysfunction, and abnormal pupillary response. Decreased is usually due to an eye abnormality. However, it can also be related other disorders affecting the pathway, from retina occipital lobe. Ocular dysfunction may follow cranial nerves responsible for movements (ie, oculomotor, trochlear, abducens nerves); any abnormality...