A5024776885- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Acute Ischemic Stroke Management
- Brain Metastases and Treatment
- Venous Thromboembolism Diagnosis and Management
- Surgical Simulation and Training
- Cerebral Venous Sinus Thrombosis
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Esophageal Cancer Research and Treatment
- Esophageal and GI Pathology
- Cerebrospinal fluid and hydrocephalus
- Vascular Malformations Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Mathematical Biology Tumor Growth
- Epilepsy research and treatment
- Peripheral Nerve Disorders
- Cancer, Hypoxia, and Metabolism
- Gastric Cancer Management and Outcomes
- Aortic Disease and Treatment Approaches
- Connective tissue disorders research
- Spine and Intervertebral Disc Pathology
- Peripheral Artery Disease Management
- Thyroid and Parathyroid Surgery
Florida College
2024
University of Florida
2024
Mayo Clinic in Florida
2019-2024
Jacksonville College
2019-2023
WinnMed
2020-2023
Neurological Surgery
2022-2023
Georgia Institute of Technology
2022
Medical University of South Carolina
2022
OBJECTIVE The authors’ goal was to use a multicenter, observational cohort study determine whether supramarginal resection (SMR) of FLAIR-hyperintense tumor beyond the contrast-enhanced (CE) area influences overall survival (OS) patients with isocitrate dehydrogenase–wild-type (IDH-wt) glioblastoma after gross-total (GTR). METHODS medical records 888 aged ≥ 18 years who underwent GBM between January 2011 and December 2017 were reviewed. Volumetric measurements CE surrounding performed,...
Recent studies have proposed resection of the T2 FLAIR hyperintensity beyond T1 contrast enhancement (supramarginal [SMR]) for IDH-wild-type glioblastoma (GBM) to further improve patients' overall survival (OS). GBMs significant variability in tumor cell density, distribution, and infiltration. Advanced mathematical models based on patient-specific radiographic features provided new insights into GBM growth kinetics two important parameters aggressiveness: proliferation rate (ρ) diffusion...
BACKGROUND AND OBJECTIVES: Bilateral/butterfly glioblastoma (bGBM) has a poor prognosis. Resection of these tumors is limited due to severe comorbidities that arise from surgical procedures. Laser interstitial thermal therapy (LITT) offers minimally invasive cytoreductive for deep-seated such as bGBM. The objective this study was evaluate the safety bilateral LITT in patients with METHODS: Medical records all consecutive diagnosed bGBM by single surgeon at institution January 2014 August...
Glioblastoma (GBM) is the most prevalent and aggressive malignant primary brain tumor. GBM proximal to lateral ventricles (LVs) more aggressive, potentially because of subventricular zone contact. Despite this, cross-talk between neural stem/progenitor cells (NSC/NPCs) not well understood. Using cell-specific proteomics, we show that LV-proximal prevents neuronal maturation NSCs through induction senescence. In addition, tumor-initiating (BTICs) increase expression cathepsin B (CTSB) upon...
Introduction: The objective of this investigation is to examine a wide array commonly accessible 3D print filaments and assess their radiographic fidelity in vertebral models. Material methods: Solid cylinders were printed on an Ultimaker S5 (Ultimaker B.V., Utrecht, Netherlands) 12 filaments: ABS (Acrylonitrile butadiene styrene), PLA (Polylactic acid), Tough PLA, PP (Poly propylene), Carbon Fiber ABS, Wood fill, PETG (Polyethylene terephthalate glycol), Nylon, PC (Polycarbonate), Bronze...
BACKGROUND AND OBJECTIVES: Despite standard of care with maximal safe resection and chemoradiation, glioblastoma (GBM) is the most common aggressive type primary brain cancer. Surgical provides a window opportunity to locally treat gliomas while patient recovering before initiating concomitant chemoradiation. The objective was assess safety establish maximum tolerated dose adipose-derived mesenchymal stem cells (AMSCs) for treatment recurrent GBM. Secondary objectives were toxicity profile...
Multiple meningiomas (MMs) occur in as many 18% of patients with meningioma, and data on progression-free survival (PFS) are scarce. The objective this study was to explore the influence number lesions clinical characteristics PFS WHO grade I meningiomas.
BACKGROUND: Loeys–Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder characterized by a classic triad of hypertelorism, bifid uvula and/or cleft palate, and generalized arterial tortuosity. There are limited data on the prevalence rupture risk intracranial aneurysms (IAs) in setting LDS, with no established guidelines. OBJECTIVE: To analyze IA LDS. METHODS: Electronic medical records patients confirmed diagnosis LDS available cerebrovascular imaging were reviewed....
Glioblastoma (GBM) is the most prevalent and aggressive malignant primary brain tumor. GBM proximal to lateral ventricles (LVs) more aggressive, potentially due subventricular zone (SVZ) contact. Despite this, crosstalk between neural stem/progenitor cells (NSC/NPCs) not well understood. Using cell-specific proteomics, we show that LV-proximal prevents neuronal maturation of NSCs through induction senescence. Additionally, tumor initiating (BTICs) increase expression CTSB upon interaction...