A5024782684- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Genetic and Kidney Cyst Diseases
- Cancer, Hypoxia, and Metabolism
- MRI in cancer diagnosis
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Renal cell carcinoma treatment
- Lymphoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Cancer Mechanisms and Therapy
- Gallbladder and Bile Duct Disorders
- Congenital Anomalies and Fetal Surgery
- Hepatitis B Virus Studies
- Medical Imaging and Pathology Studies
- Neuroendocrine Tumor Research Advances
- Abdominal vascular conditions and treatments
- Gastrointestinal disorders and treatments
- Abdominal Trauma and Injuries
- Vascular anomalies and interventions
- Radiomics and Machine Learning in Medical Imaging
- Tuberous Sclerosis Complex Research
Tokyo Metropolitan Tama Medical Center
2022
Tokyo National Hospital
2002-2017
National Cancer Centre Japan
1987-2011
Japan Breast Cancer Research Group
2007-2010
Kindai University
2010
Response Biomedical (Canada)
2010
National Cancer Center
1991-2009
Japanese Red Cross Medical Center
2008
National Cancer Center Hospital East
1992-2000
National Cancer Research Institute
1994
Background & Aims: To elucidate the survival of patients with unresectable hepatocellular carcinoma (HCC) who underwent transcatheter arterial lipiodol chemoembolization (TACE) and to analyze factors affecting survivals. Methods: During last 8 years, a nationwide prospective cohort study was performed in 8510 HCC TACE using emulsion anticancer agents followed by gelatin sponge particles as an initial treatment. Exclusion criteria were extrahepatic metastases and/or any previous treatment...
Advances in the diagnosis and surgical treatment of hepatocellular carcinoma (HCC) have improved prognosis for patients with HCC who undergo liver resection. The objective this study was to evaluate prognostic predictors underwent resection a Japanese nationwide data base.In study, authors analyzed 12,118 base between 1990 1999 compared them previous analysis 1982 1989. All were evaluated factors.During last decade, increases without hepatitis B virus surface antigen, had small tumors,...
In the 17th Nationwide Follow‐up Survey of Primary Liver Cancer in Japan, 18 213 individuals were newly registered as patients with primary liver cancer at 645 medical institutions over a period 2 years (from 1 January 2002 to 31 December 2003). Of these patients, 94.2% had hepatocellular carcinoma (HCC) and 4.1% intrahepatic cholangiocarcinoma (ICC). addition, 24 705 follow‐up survey. Epidemiological clinicopathological factors, diagnosis treatment investigated cumulative survival rates...
Early hepatocellular carcinoma (HCC) has been defined as a well–differentiated cancer containing Glisson's triad, but it remains unknown whether this lesion is curable. We prospectively studied 70 patients (enrolled from 1,172 referrals between 1982 and 1991) who had diagnosis of single HCC 2 cm or less in diameter (Stage T1) underwent curative hepatectomy long–term follow–up (range, 0.2 to 14.3 years). Patients were eligible for surgery if they tumor that met the diagnostic criteria...
Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n = 13) are expansile, roughly spheric, often encapsulated. In 2 type extranodular growth) 21), replacing growth seen the area growth. (contiguous multinodular 19) consist nodules...
Thirty-one patients with hepatocellular carcinoma (HCC) were given either an intraarterial injection of iodized poppyseed oil (Lipiodol) alone (group A, n = 6), emulsion and doxorubicin hydrochloride (Adriamycin) B, 15), or chemoembolization the same followed by gelatin sponge (Gelfoam) particles C, 10). Hepatic resection was subsequently performed. The frequencies complete necrosis tumor in main lesion, daughter tumors, thrombus, foci intracapsular invasion evaluated cut surface resected...
The diagnosis of small hepatocellular carcinomas: efficacy various imaging procedures in 100 patients.K Takayasu, N Moriyama, Y Muramatsu, M Makuuchi, H Hasegawa, Okazaki and S HirohashiAudio Available | Share
Comparison of CT Findings with Resected Specimens After Chemoembolization Iodized Oil for Hepatocellular CarcinomaKenichi Takayasu1, Shigeki Arii2, Naoki Matsuo3, Masaharu Yoshikawa4, Munemasa Ryu5, Ken Takasaki6, Morio Sato7, Yamanaka8, Yoshiyuki Shimamura9 and Masao Ohto4Audio Available | Share
In the 18th Nationwide Follow‐Up Survey of Primary Liver Cancer in Japan, 20 753 people were newly registered as patients with primary liver cancer at 544 medical institutions over a period 2 years (from 1 January 2004 to 31 December 2005). Of these patients, 94.0% had hepatocellular carcinoma (HCC) and 4.4% intrahepatic cholangiocarcinoma (ICC). addition, 30 677 follow‐up survey. Epidemiological clinicopathological factors, diagnosis treatment investigated patients. Compared 17th survey,...
The World Health Organization (WHO) criteria and Response Evaluation Criteria in Solid Tumors (RECIST) are inappropriate to assess the direct effects of treatment on hepatocellular carcinoma (HCC) by locoreginal therapies such as radiofrequency ablation (RFA) transcatheter arterial chemoembolization (TACE). Therefore, establishment response evaluation solely devoted for HCC is needed urgently clinical practice well trials treatment, molecular targeted therapies, which cause necrosis tumor....
In the 16th nationwide follow-up survey of primary liver cancer, 19,920 patients were newly registered as with cancer at 795 medical institutions in Japan over a period 2 years (from January 1, 2000 to December 31, 2001). Of these patients, 94.5% had hepatocellular carcinoma (HCC) and 3.6% intrahepatic cholangiocarcinoma (ICC). addition, 21,268 registered, valid response rate 75.6% was obtained patients. this study, epidemiological clinicopathological factors, diagnosis treatment...
OBJECTIVE. We assessed the local recurrence rate after a single targeted transarterial oily chemoembolization for small hepatocellular carcinoma with unified helical CT and angiography system analyzed factors affecting survival Cox proportional hazards model.
The purpose of this study was to determine the sensitivity CT in detecting early hepatocellular carcinoma and evaluate its appearance. An is a nodular lesion with no fibrous capsule composed well-differentiated tumor histologically. It differs from small carcinoma, which an overt that moderately poorly differentiated has capsule. Size not criterion for distinguishing between carcinomas. Thirty-one patients 39 histopathologically proved carcinomas (mean diameter, 1.7 cm) found by sonography,...
Bile duct necrosis because of transcatheter hepatic arterial embolization (THAE) in two patients with hepatocellular carcinoma is reported. Preoperative THAE was performed on 29 patients, and bile experienced by the (7%). In these gelatin (Gelfoam) powder used as embolus. Among 24 whose embolus clear, four were embolized powder. Therefore, incidence after 50%. Because hazards severe complications such necrosis, we conclude that should not be except for no more than one segment liver.
PURPOSE: To use computed tomography (CT) during arterial portography (CTAP) and CT arteriography to compare the hemodynamic properties of early hepatocellular carcinoma (HCC) with those small HCC. MATERIALS AND METHODS: Forty-four HCCs (mean diameter, 1.5 cm) in 37 patients (26 men 11 women aged 52-74 years; mean age, 59.2 years) were studied. CTAP was performed on 35 HCCs, 20, both studies 11. CTAP, arteriography, or 90 2.0 57 (44 13 48-71 61 years). The findings for HCC compared RESULTS:...