A5000577946- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Retinal Development and Disorders
- Retinal Imaging and Analysis
- Breast Lesions and Carcinomas
- Ocular Diseases and Behçet’s Syndrome
- Ocular Surface and Contact Lens
- Breast Cancer Treatment Studies
- Ocular Infections and Treatments
- Corneal surgery and disorders
- Intraocular Surgery and Lenses
- MRI in cancer diagnosis
- Corneal Surgery and Treatments
- Ocular Oncology and Treatments
- Drug-Induced Ocular Toxicity
- Nutritional Studies and Diet
- Nasolacrimal Duct Obstruction Treatments
- Ultrasound and Hyperthermia Applications
- Retinal and Macular Surgery
- Cancer and Skin Lesions
- Global Cancer Incidence and Screening
- Colorectal Cancer Treatments and Studies
- Prenatal Substance Exposure Effects
- Ultrasound Imaging and Elastography
Mie University
2016-2025
Weatherford College
2021-2024
Fukui-ken Saiseikai Hospital
2020-2023
Kawasaki University of Medical Welfare
2022
Kawasaki Medical School
2022
Alcon (China)
2021
Bayer (United States)
2021
Noguchi Thyroid Clinic and Hospital Foundation
2019
Osaka City University
2017
Jikei University School of Medicine
2008-2016
Abstract We examined the dietary intake and sources of isoflavones (daidzein genistein) among Japanese subjects based on records (DRs). The comprised two groups: 1,232 who completed one-day DRs (Group 1) 88 men women kept four four-day (16-day) DRs. For quantitative data level daidzein genistein in soy foods, we extensively reviewed literature, particularly for adopted median value each food. was 12.1 9.5 mg/day Groups 1 2, respectively, while corresponding values were 19.6 14.9 mg/day. top...
Abstract Diabetic retinopathy (DR) is a leading cause of blindness among working-age adults. Therefore, it important to detect DR accurately during mass screening. The purpose this study was determine whether small, hand-held, mydriasis-free, full-field flicker electroretinographic (ERGs) device called RET eval can be used screen for DR. To accomplish this, we recorded ERGs with from 48 normal eyes and 118 different severities in patients diabetes mellitus (DM). This system delivered...
Inherited retinal diseases (IRDs) comprise a phenotypically and genetically heterogeneous group of ocular disorders that cause visual loss via progressive degeneration. Here, we report the genetic characterization 1210 IRD pedigrees enrolled through Japan Eye Genetic Consortium analyzed by whole exome sequencing. The most common phenotype was retinitis pigmentosa (RP, 43%), followed macular dystrophy/cone- or cone-rod dystrophy (MD/CORD, 13%). In total, 67 causal genes were identified in 37%...
A self-administered 97-item simple food frequency questionnaire (FFQ), without portion size questions for most items, was completed twice at an one-year interval by 88 men and women in central Japan to evaluate its reproducibility. This FFQ further validated referring four 4-day weighed dietary records (DRs) which were performed 3-month intervals. Mean energy 18 nutrient intakes measured the first second FFQs quite similar those DRs. In our reproducibility study, Pearson intraclass...
We developed a simple food frequency questionnaire (FFQ) based on one-day dietary records (DRs) among 1001 subjects in Nagoya, Japan. A total of 97 foods and dishes were selected through two-step procedure; first by ranking items according to the contribution population intake nutrient variables, second stepwise multiple regression analyses individual as independent variables dependent variables. For simplicity, questions portion sizes not included except for few items, which resulted short...
To determine the effects of topical diclofenac or betamethasone with concomitant application rebamipide on conjunctival goblet cell density in eyes after cataract surgery.Randomized clinical trial.Eighty patients who were scheduled for surgery.Patients randomized into 4 groups according to postoperative drugs be given; Group A, alone; B, and rebamipide; C, D, rebamipide. Impression cytology was performed before at 1 month surgery, mean cells determined.The (± SD) surgery A 257.0 ± 188.7...
Abstract To determine the parameters of anterior segment eyes that are significantly associated with refractive error in healthy young Japanese university students. This was a cross-sectional observational study 229 students (men: women,147:82) whose age ranged between 20 to 29 years. Univariate and multivariate linear regression analyses were performed identify factors correlated error. The independent variables included age, sex, axial length, chamber depth, corneal diameter, curvature...
To report our findings in a rare case of unilateral endophthalmitis caused by Rhizobium radiobacter healthy young man complicated rupture the lens capsule and rhegmatogenous retinal detachment (RRD). A 22-year-old Cambodian presented with recurrent blurry vision left eye, following two-year history uveitis initially responsive to corticosteroid treatment. However, during second recurrence, corticosteroids failed control inflammation. At initial examination, non-granulomatous keratic...
Since 2015, hydroxychloroquine (HCQ) has been widely used as a standard treatment for systemic lupus erythematosus (SLE) and cutaneous (CLE) under the national health insurance system in Japan. However, status of routine ophthalmological screening retinopathy, which is notable safety concern HCQ, remains unclear. In this retrospective study using nationwide claims database, we aimed to investigate clinical practice A total 2567 patients with SLE or CLE were included analysis. The proportion...
The half-life of anti-vascular endothelial growth factor (anti-VEGF) drugs shortens significantly after vitrectomy due to an increased intraocular pharmacokinetic clearance caused by the absence vitreous gel. This reduced can limit therapeutic effect these intravitreal agents and complicate management conditions such as neovascular age-related macular degeneration (nAMD). We report a case nAMD in vitrectomized eye that showed inadequate response both aflibercept brolucizumab, but experienced...
Congenital stationary night blindness (CSNB) is a non-progressive, clinically and genetically heterogeneous disease of impaired vision. We report naturally-occurring, stationary, autosomal recessive phenotype in beagle dogs with normal daylight vision but absent Affected had retinas on clinical examination, showed no detectable rod responses. They “negative-type” mixed cone responses full-field ERGs. Their photopic long-flash ERGs OFF-responses associated severely reduced ON-responses. The...
Purpose: A small, full-field flicker electroretinogram (ERG) recording system was recently developed to record ERGs without mydriasis (RETeval). The device delivers a stimulus with constant retinal illuminance by adjusting the luminance compensate for changes in pupillary area. purpose of this study determine what factors affect fundamental components recorded RETeval young healthy subjects. Methods: Flicker were from 150 eyes subjects (age, 20–29 years). Univariate and multivariate linear...
Purpose: To determine the clinical characteristics, prognosis, and effect of anti-vascular endothelial growth factor (VEGF) agents on eyes with a central retinal vein occlusion (CRVO) without supernormal flicker ERG amplitudes. Methods: Forty-eight 48 patients CRVO were studied. Flicker ERGs recorded from fully dilated RETeval system. The amplitudes implicit times fundamental component analyzed. "Supernormal ERGs" defined as those whose ≥117% unaffected fellow eyes. Results: Ten (20.8%)...
To determine the characteristics of an eye that developed acute hydrops while being treated for infectious keratitis. A 35-year-old man presented with pain and blurred vision in his left eye. He had undergone cataract surgery seven years earlier was poorly controlled atopic dermatitis. The decimal best-corrected visual acuity (BCVA) 0.01. Slit-lamp microscopy showed conjunctival injection, corneal opacification, a ulcer. patient diagnosed keratitis topical systemic antibiotics. During...
Intraocular inflammations (IOIs) have been reported to occur after intravitreal injections of brolucizumab, and one their causes has suggested be drug-specific features. We evaluated the anterior chamber by aqueous flare value (AFV) retina flicker electroretinography (ERG) initial injection aflibercept (IVA), brolucizumab (IVBr), or faricimab (IVF) for neovascular age-related macular degeneration (nAMD). The AFV ERGs were determined before, 2 weeks after, 4 in 14 eyes patients each drug....
BACKGROUND: A community-based survey was conducted to investigate reproductive tract infections (RTIs) among pregnant women in Vietnam, where epidemiologic data on these are scarce.METHODS: The focus of the study were: candidiasis, bacterial vaginosis, group B streptococcal infection,trichomoniasis, gonorrhea, syphilis, and hepatitis B. In addition their prevalence, a generalized estimating equation used analyze infection-associated factors diagnostic test analysis examine accuracy currently...
Background: A congenital nasolacrimal duct obstruction (CNLDO) is a relatively common disease in infants. We evaluated the results of probing three patients with CNLDO, under direct view, dacryoendoscope. Methods: Three cases CNLDO were examined and treated by dacryoendoscope, intravenous anesthesia. The diameter dacryoendoscope probe was 0.7 mm, we able to observe inner walls lacrimal guide through duct. Results: In all cases, site detected, used remove obstruction. At 2 weeks after removal...
Purpose: To determine whether there is a significant correlation between the amplitude of photopic negative response (PhNR) and peripapillary retinal nerve fiber layer thickness (pRNFLT) in eyes young, healthy subjects. Methods: We analyzed 136 subjects (89 males 47 females; age, 20–29 years). The PhNRs were recorded with RETeval system without mydriasis using red flashes on blue background. PhNR was measured at two points: 72 ms (P72) trough following b-wave (Pmin). Univariate multivariable...
To compare the effectiveness of intravitreal ranibizumab (IVR) and aflibercept (IVA) performed with treat-and-extend (TAE) regimen on eyes diabetic macular edema (DME).This is a retrospective study 125 treatment-naïve DME patients who received anti-VEGF injections at three consecutive monthly intervals as loading phase. The changes in best-corrected visual acuity (BCVA), central retinal thickness (CRT), retinopathy severity scale (DRSS), total injection numbers were compared between two...
Objectives This study was performed to evaluate the diagnostic utility of quantitative analysis benign and malignant breast lesions using contrast‐enhanced sonography. Methods Contrast‐enhanced sonography perflubutane‐based contrast agent Sonazoid (Daiichi Sankyo, Tokyo, Japan) in 94 pathologically proven palpable mass lesions, which could be depicted with B‐mode Quantitative analyses time‐intensity curve on were 5 region interest (ROI) types (manually traced ROI circular ROIs 5, 10, 15, 20...