A5035751011- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Cancer Diagnosis and Treatment
- MicroRNA in disease regulation
- Cancer Cells and Metastasis
- Cancer and Skin Lesions
- Metastasis and carcinoma case studies
- Thyroid Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Medical Imaging and Pathology Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Colorectal and Anal Carcinomas
- Cancer Treatment and Pharmacology
- Cancer-related molecular mechanisms research
- Colorectal Cancer Screening and Detection
- Diverticular Disease and Complications
- Intraperitoneal and Appendiceal Malignancies
- HER2/EGFR in Cancer Research
- Pancreatic and Hepatic Oncology Research
Jikei University School of Medicine
2016-2025
Suita Municipal Hospital
2014-2025
Toyonaka Municipal Hospital
2020-2024
Minoh City Hospital
2014-2023
University of Hyogo
2020-2022
Kindai University
2015-2018
Osaka University
2013-2017
Osaka International Cancer Institute
2014
Nishinomiya Municipal Central Hospital
2014
Kansai Rosai Hospital
2014
Although lenvatinib is the preferred treatment for unresectable radioactive iodine-refractory differentiated thyroid cancer (RR-DTC), this agent exerts considerable toxicities, which can lead to frequent dose interruptions and modifications. The adoption of planned drug holidays has been recently suggested as one means minimizing or avoiding these severe adverse events. Our retrospective study demonstrated that appear be a promising strategy continuing lenvatinib. However, benefits in...
Studies have shown the prognostic significance of disseminated tumor cells (DTC) in bone marrow patients with colorectal cancer. However, molecular characteristics DTCs, including their miRNA expression profiles, remain mostly unknown. In this study, we analyzed DTCs marrow. EpCAM(+) were collected using immunomagnetic beads after exclusion CD14(+) and CD45(+) cells, then subjected to microarray analysis. Cluster analysis (7 cancer liver metastasis 12 without metastasis) indicated that...
Granulomatous mastitis (GM) is a rare chronic inflammatory breast condition with unknown etiology. There still no generally accepted optimal treatment for GM. Corticosteroid and/or wide excision most commonly reported in the literature. Incision and drainage or limited alone has little benefit because of strong tendency recurrence. Corticosteroids also have high failure rate possible side effects. In current series, we treated GM patients without corticosteroids, except one patient. We...
Elevated fibronectin levels have been observed in various cancers; however, whether they are related to the actual malignancy remains controversial. We herein measured blood of sialic acid-fibronectin (S-FN), a type autocrine cellular secreted by breast cancer cells and investigate S-FN secretion is associated with through epithelial-mesenchymal transition (EMT), as well recurrent metastasis. Blood was detected samples from 82 patients carcinoma using ELISA. Vimentin immunostaining performed...
Abstract Aim There has been no prospective multicentre validation of the treatment outcomes minimally invasive lateral pelvic lymph node dissection for lower rectal cancer; hence, this study aimed to evaluate prophylactic laparoscopic dissection. Method Between May 2018 and August 2021, 90 patients with Stage II–III cancer were registered. The clearance range included nodes around internal iliac artery obturator nodes, while autonomic nerves generally preserved. primary outcome was incidence...
Tumor progression is the main cause of death in patients with breast cancer. Accumulating evidence suggests that dual-specificity tyrosine-regulated kinase 2 (DYRK2) functions as a tumor suppressor by regulating cell survival, differentiation, proliferation and apoptosis. However, little known about mechanisms transcriptional regulation DYRK2 cancer progression, particularly respect to invasion. Here, using comprehensive expression profiling approach, we show cyclin-dependent 14 (CDK14)...
For this study, we investigated the usefulness of MDCT in assessing extent residual breast cancer after neoadjuvant chemotherapy. To ensure success breast-conserving surgery, evaluated determining tumor distribution before chemotherapy and shrinkage pattern chemotherapy.MDCT was performed 46 consecutive patients with 47 locally advanced cancers. The contrast enhancement on classified into five categories: solitary lesion, grouped lesion (localized linear, spotty, or linear spotty...
Sentinel node biopsy (SNB) is used to accurately assess axillary lymph status in patients with node-negative breast cancer. However, its use after neoadjuvant chemotherapy (NAC) controversial. We retrospectively assessed the usefulness of SNB NAC by comparing recurrence rates and other parameters clinically cancer who underwent or without NAC.At our hospital, 1179 from April 2007 December 2013. The clinicopathological survival data (the group) those control were compared. Patients a...
To compare the usefulness of self-expanding metallic stent (SEMS) with that transanal drainage tube (TDT) and emergency surgery after failure decompression (ESFD) in patients malignant colonic obstruction (MCO), to evaluate post-decompression histopathologic changes.From January 2010 June 2015, 39 MCO received SEMS, TDT, ESFD. We evaluated outcomes including success rates placement, clinical decompression, findings resected specimens.Technical were 100% for SEMS 78.9% TDT. Clinical 80.0%...
Abstract Background Vaccination with fusion cells (FCs) comprising dendritic and tumour as well administration of interleukin‐12 (IL‐12) showed a significant therapeutic effect against established tumours in mouse experimental models. We conducted immunotherapy various malignant using the FCs rhIL‐12, investigated safety efficacy therapy. Materials methods Patients’ DCs were mixed autologous irradiated treated 50% polyethylene glycol to generate FCs. The inoculated intradermally, then 30 ng...
This study aimed to evaluate the clinical outcomes of chest wall reconstruction using a relatively new expanded polytetrafluoroethylene prosthesis Gore-Tex(®) dual mesh.We reviewed charts 11 patients who underwent bony resection from April 2006 January 2011.Six three ribs resection, two and other sternal resection. Of six after 2 mm mesh, one Gore-Tex(®), Bard composite E/X, remaining used no prosthesis. Three Two mesh with or without vascularized musculocutaneous pedicle flap. Immediate...
Disseminated carcinomatosis of the bone marrow (DCBM) is a condition in which (BM) metastases diffusely invade BM, and frequently accompanied by disseminated intravascular coagulation (DIC). While prostate, lung, breast stomach malignancies, addition to neuroblastoma, are most prevalent non-hematological malignancies metastasize colorectal cancer malignancy that rarely metastasizes BM. The present case describes 65-year-old male patient treated resection one course adjuvant chemotherapy for...