A5043696277- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Metabolomics and Mass Spectrometry Studies
- Geoscience and Mining Technology
- Geochemistry and Geochronology of Asian Mineral Deposits
- Risk and Safety Analysis
- Cancer, Hypoxia, and Metabolism
- Geomechanics and Mining Engineering
- Advanced Sensor and Control Systems
- Fault Detection and Control Systems
- Geochemistry and Geologic Mapping
- Management of metastatic bone disease
- Membrane Separation Technologies
- Smart Grid Security and Resilience
- Smart Grid and Power Systems
- Lung Cancer Research Studies
- Occupational Health and Safety Research
- Advanced Computational Techniques and Applications
- Civil and Geotechnical Engineering Research
- Manufacturing Process and Optimization
- Advanced NMR Techniques and Applications
- Geological and Geochemical Analysis
- Advanced Algorithms and Applications
- Human Pose and Action Recognition
- Power Systems and Technologies
University of Alberta
2023-2025
Wuhan No.1 Hospital
2023-2025
Guangdong Polytechnic Normal University
2024
University of Science and Technology of China
2018-2024
China Academy of Space Technology
2022-2024
CAS Key Laboratory of Urban Pollutant Conversion
2024
Memorial University of Newfoundland
2021-2023
META Health
2023
State Grid Hunan Electric Power Company Limited
2023
Suzhou University of Science and Technology
2022
In vehicular ad-hoc networks (VANETs), safety messages are exchanged among vehicles and between infrastructure to ensure passengers' efficiency in traffic. The source authentication as well integrity checking of these very necessary for a receiver. Based on certificateless cryptography (CLC), some state-of-the-art signature schemes have been proposed address these. Although they fulfill the requirements privacy, not efficient with respect performance. Bilinear pairings map-to-point hash...
Sungsanpin (1), a new 15-amino-acid peptide, was discovered from Streptomyces species isolated deep-sea sediment collected off Jeju Island, Korea. The planar structure of 1 determined by 1D and 2D NMR spectroscopy, mass spectrometry, UV spectroscopy. absolute configurations the stereocenters in this compound were assigned derivatizations hydrolysate with Marfey's reagents 2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl isothiocyanate, followed LC-MS analysis. Careful analysis ROESY spectrum...
Abstract Cell growth and survival depend on a delicate balance between energy production synthesis of metabolites. Here, we provide evidence that an alternative mitochondrial complex II (CII) assembly, designated as CII low , serves checkpoint for metabolite biosynthesis under bioenergetic stress, with cells suppressing their utilization by modulating DNA cell cycle progression. Depletion leads to imbalance in synthesis, evidenced recovery the de novo pyrimidine pathway unlocking arrest from...
Vehicular ad-hoc networks (VANETs) enable vehicles to exchange safety information with the surrounding and infrastructure in order ensure efficiency traffic management. Recently however, come from different manufacturers therefore use protocols for transmission of messages. As a result, communication among become heterogeneous. Because this, VANETs face problems related security performance. To address some heterogeneous vehicular communication-based schemes have been proposed. However, they...
Correct identification of the origins herbal medical products is becoming increasingly important in tandem with growing interest alternative medicine. However, visual inspection raw material still most widely used method, and newer scientific approaches are needed. To develop a more objective efficient tool for discriminating origins, particularly Korean Chinese, we employed nuclear magnetic resonance (NMR)-based metabolomics approach combined an orthogonal projections to latent...
Abstract Altered metabolism is a critical part of cancer cell properties, but real‐time monitoring metabolomic profiles has been hampered by the lack facile method. Here, we propose live cells using 13 C 6 ‐glucose and heteronuclear two‐dimensional (2D) NMR. The method allowed for differentiation between normal on basis time‐dependent changes in metabolite concentrations. Cancer were found to have large in‐ out‐flux pyruvate as well increased net production alanine acetate. also enabled...
Leptomeningeal carcinomatosis (LC) is a metastatic cancer invading the central nervous system (CNS). We previously reported metabolomic diagnostic approach as tested on an animal model and compared with current modalities. Here, we provide proof of concept by applying it to human LC originating from lung cancer, most common cause CNS metastasis. Cerebrospinal fluid (n = 26) normal groups 41) were obtained, diagnosis was established clinical signs, cytology, MRI biochemical tests. The...
Significance We introduce an in-organelle live NMR metabolomics approach that allows for real-time metabolic monitoring of human mitochondria. The also features more than order magnitude higher sensitivity and much less overlap conventional methods. capability identified acetyl phosphate in mitochondria showed its biphasic kinetic profile typical a reaction intermediate. method allowed estimation pyruvate dehydrogenase enzyme activity according to p53 status, independent competing cytosolic...
Interstitial cystitis/painful bladder syndrome (IC) is a chronic of unknown etiology that presents with pain, urinary frequency, and urgency. The lack specific biomarkers poor understanding underlying molecular mechanisms present challenges for disease diagnosis therapy. goals this study were to identify noninvasive biomarker candidates IC from urine specimens potentially gain new insight into using nuclear magnetic resonance (NMR)-based global metabolomics analysis female patients controls....
The conflict between human and artificial intelligence is a critical issue, which has recently been introduced in Process System Engineering, capturing the observation action conflicts. Interpretation another source of potential that can cause serious concern for process safety as it often perceived confusion, surprise, or mistake. It intangible associated with situation awareness. However, interpretation not studied required emphasis. current work proposes novel methodology to quantify...
Objective:To explore the influence of voice training combined with active breathing and circulation techniques on recovery following vocal cord polyp surgery. Methods:A total 110 patients who underwent surgery at our hospital from May 2022 to November 2023 were selected randomly divided into a control group （n=55） combination using random number table method. During period, both groups received dietary aerosol treatment. The participated in training, while addition for 2 months....
Adrenal tumors are a common type of tumor whose incidence increases with age. This study aims to apply the continuous nursing mode "Internet Plus" patients severe adrenal tumors, and preliminarily evaluate effect intervention based on tumors. A single-center, retrospective, observational was carried out patients. total 128 admitted our hospital from June 2020 August 2021 were selected divided into 2 groups: observation group (n = 64) received routine care control continuing Plus." The first...
Dietary restriction (DR) has many beneficial effects, but the detailed metabolic mechanism remains largely unresolved. As diet is essentially related to metabolism, we investigated metabolite profiles of urines from control and DR animals using NMR LC/MS metabolomic approaches. Multivariate analysis presented distinctive marker signals glucuronide glycine conjugation pathways in group. Broad profiling urine phase II metabolites with neutral loss scanning showed that levels were generally...
Isotopomer analysis using either 13C NMR or LC/GC–MS has been an invaluable tool for studying metabolic activities in a variety of systems. Traditional challenges are, however, that 13C-detected is insensitive despite its high resolution, and MS-based techniques cannot easily differentiate positional isotopomers. In addition, current limitations detecting metabolites living cells. Here, we describe non-uniform sampling-based 2D heteronuclear single quantum coherence (NUS HSQC) approach to...
Alterations in metabolic pathways are gaining attention as important environmental factors affecting life span, but the determination of specific and enzymes involved span remains largely unexplored. By applying an NMR-based metabolomics approach to a calorie-restricted yeast (Saccharomyces cerevisiae) model, we found that alanine level is inversely correlated with chronological span. The involvement alanine-metabolizing pathway was tested using deletion mutant ALT1, gene for key enzyme....
Hydrogen is an important energy carrier for the transition to a carbon-neutral society, efficient separation and purification of hydrogen from gaseous mixtures critical step implementation economy. In this work, graphene oxide (GO) tuned polyimide carbon molecular sieve (CMS) membranes were prepared by carbonization, which show attractive combination high permeability, selectivity stability. The gas sorption isotherms indicate that capability increases with carbonization temperature follows...
The urgent need for CO