- Cardiovascular Health and Risk Factors
- Systemic Lupus Erythematosus Research
- Cancer Mechanisms and Therapy
- Bone and Dental Protein Studies
- Salivary Gland Disorders and Functions
- Ubiquitin and proteasome pathways
- Glycosylation and Glycoproteins Research
- Multiple Sclerosis Research Studies
- Blood Pressure and Hypertension Studies
- Breast Cancer Treatment Studies
- Cardiac Health and Mental Health
- Renal Diseases and Glomerulopathies
- Sulfur Compounds in Biology
- Gout, Hyperuricemia, Uric Acid
- Psoriasis: Treatment and Pathogenesis
- Spinal Fractures and Fixation Techniques
- Liver Diseases and Immunity
- Mycobacterium research and diagnosis
- Salivary Gland Tumors Diagnosis and Treatment
- Nuts composition and effects
- Thyroid Cancer Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Advanced Breast Cancer Therapies
- Global Financial Crisis and Policies
- Chinese history and philosophy
The University of Texas Medical Branch at Galveston
2025
Pudong Medical Center
2024
Fudan University
2018-2024
Foshan University
2024
Dhurakij Pundit University
2024
Weatherford College
2023
Patients First
2023
Peking University
2022-2023
East China Normal University
2023
Zhejiang Chinese Medical University
2023
In recent years, more and studies have shown that internet-based health management can help patients with hypertension control their blood pressure. However, there is a lack of similar research in China.We designed this study to clarify the impact long-term on clinical parameters hypertension. These results are also expected identify relevant factors affecting accurately toward developing targeted strategies.This was longitudinal five provinces northwest China. The inclusion criteria were...
Gastroesophageal cancer (GEAC) consists of upper GI malignancies the esophagus, gastroesophageal junction, or stomach. Despite recent advancements in treatment modalities, GEAC remains a major health burden and listed as second leading cause cancer-related deaths globally. poses significant challenge with short survival lack effective therapeutics. Thus, uncovering novel targets is urgent need. Cyclin-dependent kinase 9 (CDK9), one transcription-associated CDKs, has been implicated...
This study aimed to examine the relationship between anxiety, depression, sleep quality and health-related of life among systemic lupus erythematosus (SLE) patients in China.After ethical approval obtaining participants' informed consent, a cross-sectional was conducted The First Affiliated Hospital Anhui Medical University October 1, 2021 January 30, 2022. data comprised demographic information, number SLE symptoms, Anxiety Depression Scale (HADS), Pittsburgh Sleep Quality Index (PSQI)...
Background Lactopontin (LPN) in breast milk, also known as milk osteopontin is thought to play a myriad of important roles infants when they are immature. The purpose the present study was examine longitudinal changes LPN concentrations term and preterm elucidate links between maternal characteristics, levels, child growth birth cohort. Methods 131 mothers who delivered term, moderate-late (MPT), very (VPT), extremely (EPT) were included, samples collected at 7, 14, 28, 120 days postpartum....
An efficient and convenient approach for one-pot synthesis of 3-substituted chroman-2,4-diones via a three-component reaction aromatic aldehydes, 4-hydroxy- coumarins diverse pyrazolone derivatives was described. The combinatorial this methodology achieved by applying ultrasound irradiation in the absence activator while making use water as green solvent. Additionally, novel chroman-2,4-dione attached to an edaravone moiety represent exploitable source brand new anticancer agents. In...
Background: Primary Sjögren's syndrome (pSS) is an autoimmune disease with lymphocytic infiltration of the salivary and lachrymal glands, whose present disease-specific objective indicators are few have shortcomings that should be addressed. An integrated analysis sequencing data from different cohorts has potential to unveil novel biomarkers in pSS. Methods: We identified 3 GEO datasets, including gene expression minor gland (MSG) biopsy samples 49 patients pSS 31 non-pSS whole blood cells...
Abstract Aim Sjögren syndrome (SS) is a slowly progressive, inflammatory, autoimmune disease. The aim of this study was to construct the DNA methylation profiles whole blood SS patients and healthy controls (HC), explore role differentially methylated genes in pathogenesis Methods Whole‐genome bisulfite sequencing performed on three four HC. biological function associated with regions (DMRs) investigated using Gene Ontology functional analysis Kyoto Encyclopedia Genes Genomes pathway...
The coexistence of Sjögren's syndrome (SS) and Hashimoto thyroiditis (HT) has been confirmed, but the common mechanism its co-occurrence remains unknown. This study aims to further explore underlying biomarkers for SS HT. Gene Expression Omnibus databases were used obtain gene expression profiles (GSE127952 GSE23117) HT (GSE29315 GSE138198). Following identifying HT's shared differentially expressed genes, functional annotation, protein-protein interaction network creation, module assembly...
In China, WeChat has become an excellent place for Chinese tourists to share their travel products and experiences nowadays due its wide audience, high usage rate, immediacy. According the 49th Statistical Report on Development of Internet in as December 2021, number social media users China reached 1.007 billion, accounting 97.5% overall users. 43.8% use “share lives or opinions”, indicating that is currently most widely used representative China. With advent 5G era, platform will further...
In the past two years, new funds issuance has been extremely hot, and total scale of public offering also increased significantly. Behind hot funds, it gave birth to a number “hotstyle” funds. But at same time, have encountered large redemption phenomenon, making young investors get title “leek zero”. This paper returns quarterly data 28 money market analyzes factors affecting fund liquidity risk, obtains relationship between each influencing factor risk fund. Then put forward establishment...
Abstract Background: Tumor necrosis factor receptor associated 3 (TRAF3) and deubiquitinating enzyme ubiquitin-specific protease 33 (USP33) have been identified to play important roles in inflammatory diseases, including acute pancreatitis (AP). Here, we aimed explore whether USP33 affected AP progression by affecting TRAF3 expression through deubiquitination. Methods: Caerulein-treated HPDE6-C7 cells were used mimic conditions vitro . Levels of mRNAs proteins examined qRT-PCR Western blot....