Kuan Zhang

ORCID: 0000-0003-4195-1198
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Research Areas
  • Total Knee Arthroplasty Outcomes
  • Lower Extremity Biomechanics and Pathologies
  • Knee injuries and reconstruction techniques
  • Osteoarthritis Treatment and Mechanisms
  • Balance, Gait, and Falls Prevention
  • Herpesvirus Infections and Treatments
  • Diabetic Foot Ulcer Assessment and Management
  • T-cell and Retrovirus Studies
  • Crop Yield and Soil Fertility
  • Muscle activation and electromyography studies
  • Cytomegalovirus and herpesvirus research
  • Orthopaedic implants and arthroplasty
  • Musculoskeletal pain and rehabilitation
  • Infrared Thermography in Medicine
  • Colorectal Cancer Surgical Treatments
  • Clinical practice guidelines implementation
  • Tribology and Wear Analysis
  • Sports injuries and prevention
  • Scoliosis diagnosis and treatment
  • Bone fractures and treatments
  • Viral-associated cancers and disorders
  • Lung Cancer Diagnosis and Treatment
  • Advanced Sensor and Energy Harvesting Materials
  • Heavy Metal Exposure and Toxicity
  • COVID-19 diagnosis using AI

Capital Medical University
2015-2025

Army Medical University
2015-2025

Changzhou University
2025

Qinghai Red Cross Hospital
2008-2024

Sichuan Agricultural University
2024

Beijing Aerospace Flight Control Center
2020-2024

Beijing Luhe Hospital Affiliated to Capital Medical University
2023

National Research Center for Rehabilitation Technical Aids
2023

WinnMed
2021-2022

University of Nebraska–Lincoln
2022

Abstract Objectives: To validate a new device, Intelligent Device for Energy Expenditure and Activity (IDEEA), the measurement of duration, frequency, intensity various types human physical activity (PA). Research Methods Procedures: The ability IDEEA to identify quantify 32 PA, including most common daily exercise nonexercise was tested in 76 subjects: Subjects included males ( N = 33) females 43) ranging age from 13 72 years with mean body mass index (BMI) 24.7 kg/m 2 (range: 18.4 41.0)...

10.1038/oby.2003.7 article EN Obesity Research 2003-01-01

Welding usually involves high temperatures, toxic solvents, or conditions not compatible with human bodies, which severely limit the fusion of electronics and tissues. To achieve direct welding on skin, intrinsically sticky conductors that can simultaneously metal-grade electrical conductivity (≈41 7000 S m

10.1002/advs.202202043 article EN cc-by Advanced Science 2022-06-26

Yutu-2 rover conducted an exciting expedition on the 41st lunar day to investigate a fin-shaped rock at Longji site (45.44°S, 177.56°E) by extending its locomotion margin perilous peaks. The varied encountered, especially multi-form wheel slippage, during journey target rock, established unique conditions for fin-grained regolith analysis regarding bearing, shear and lateral properties based terramechanics. Here, we show tri-aspect characterization of infer rock's origin using digital twin....

10.1038/s41467-024-46233-8 article EN cc-by Nature Communications 2024-03-08

10.1093/ajcn/81.6.1335 article EN publisher-specific-oa American Journal of Clinical Nutrition 2005-06-01

3510 Background: It’s presented the results of a phase III trial short-term radiotherapy (SCRT) combined with chemotherapy versus long-term chemoradiotherapy (LCRT) in patients locally advanced rectal cancer (LARC). Methods: Patients distal or middle third, T3-T4 and/or N+ adenocarcinomas diagnosed by MRI, were randomly assigned to experimental group control group. In group, received SCRT (25 Gy / 5 fractions days), followed four courses CAPOX. LCRT (50 25 35 days concurrent capecitabine)....

10.1200/jco.2021.39.15_suppl.3510 article EN Journal of Clinical Oncology 2021-05-20

Abstract Background Bovine herpesvirus type 1 (BHV-1) is an important pathogen in cattle that responsible for substantial economic losses. Previous studies suggest BHV-1 may induce apoptosis Madin-Darby bovine kidney (MDBK) cells via a mechanism only involving caspases and p53. However, the BHV-1-induced MDBK cell still requires more research. Methods was used as model to study precise signaling pathways of induced by infection. Results infection activated Fas/FasL-mediated apoptotic...

10.1186/1743-422x-9-202 article EN cc-by Virology Journal 2012-09-17

Midbrain dopamine (DA) neurons are essential for maintaining multiple brain functions. These have also been implicated in relation with diverse neurological disorders. However, how these developed from neuronal stem cells (NSCs) remains largely unknown. In this study, we provide both vivo and vitro evidence that the thyroid hormone, an important physiological factor development, promotes DA neuron differentiation embryonic ventral midbrain (VM) NSCs. We find hormone deficiency during...

10.1089/scd.2014.0489 article EN Stem Cells and Development 2015-04-13

Muscle function deterioration in female patients with severe knee osteoarthritis (KOA) is linked to alterations muscle morphology, composition, and mechanical properties. This study evaluates thigh features KOA explores correlations joint function. Ultrasound shear wave elastography measured physiological cross-sectional area (PCSA), echo intensity (EI), modulus (G) the rectus femoris (RF), vastus lateralis (VL), medialis (VM), biceps long head (BFL), semitendinosus (ST) of 24 controls. EI...

10.1186/s12891-025-08361-0 article EN cc-by-nc-nd BMC Musculoskeletal Disorders 2025-02-28

Kinematic alignment (KA) unicompartmental knee arthroplasty (UKA), which has not been widely adopted in clinical practice, aims to implant a more personalized and physiologically compatible mobile-bearing UKA prosthesis for the treatment of advanced single compartment osteoarthritis. KA is anticipated enhance patient satisfaction decrease revision rate following UKA. However, its quantified biomechanical indicators remain unclear. The purpose this study reveal characteristics tibiofemoral...

10.1186/s13018-025-05659-6 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2025-03-14

Abstract Imaging the behavior and fate of implanted cells is crucial in cell therapy. However, it remains challenging to achieve synchronized tracing different behaviors for same due lack a multimodal imaging probe. Herein, through flexible polypeptide linkers, S‐L‐D‐S G‐S‐S‐G, multifunctional probe constructed by fusing three proteins, including bioluminescent reporter (NanoLuc), fluorescent protein (mRuby2), calcium indicator (GCamp6f). A lentivirus carrying triple‐fusion prepared stable...

10.1002/adfm.202422870 article EN Advanced Functional Materials 2025-05-22

Abstract The rapid advancement of modern industry has led to a substantial escalation in the probability accidents involving hazardous chemicals across life cycle products, including storage, use, and disposal. increasing recognition impact toxic on human health underscores growing significance conducting research toxicity indicators. In this paper, Acute Exposure Guideline Levels (AEGL) aliphatic compounds were predicted using Quantitative Structure Activity Relationship (QSAR) method. We...

10.1093/etojnl/vgaf137 article EN Environmental Toxicology and Chemistry 2025-05-27

To diagnose pneumoconiosis using a computer-aided diagnosis system based on digital chest radiographs.Lung fields were first extracted by combining the traditional Otsu-threshold method with morphological reconstruction radiographs (DRs), and then subdivided into six non-overlapping regions (region (a-f)). Twenty-two wavelet-based energy texture features calculated exclusively from each region selected decision tree algorithm. A support vector machine (SVM) linear kernel was trained samples...

10.1186/1475-925x-13-141 article EN cc-by BioMedical Engineering OnLine 2014-10-02
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