A5100767444- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Inflammatory Biomarkers in Disease Prognosis
- Helicobacter pylori-related gastroenterology studies
- Organometallic Complex Synthesis and Catalysis
- Liver Disease Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Advanced Radiotherapy Techniques
- Galectins and Cancer Biology
- Cancer Mechanisms and Therapy
- Cancer, Hypoxia, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Metal complexes synthesis and properties
- Metastasis and carcinoma case studies
- Lung Cancer Treatments and Mutations
- Ferrocene Chemistry and Applications
- Combustion and flame dynamics
- RNA Research and Splicing
Guizhou Cancer Hospital
2013-2024
Guiyang Medical University
2017-2024
Affiliated Hospital of Guizhou Medical University
2020-2024
First Affiliated Hospital of Zhengzhou University
2023-2024
Chung Shan Medical University
2019-2024
China Medical University
2019-2023
China Medical University Hospital
2019-2023
Dalian Medical University
2022
Second Affiliated Hospital of Dalian Medical University
2022
Yancheng Teachers University
2016-2020
We compared efficacy and safety of paclitaxel/capecitabine therapy followed by capecitabine for maintenance (PACX) versus cisplatin/capecitabine (XP) in advanced gastric cancer. Multicenter, randomized, phase III trial was conducted China (December 2009–February 2014). Adults (n = 320) with histologically confirmed, untreated metastatic/unresectable or gastroesophageal junction adenocarcinoma; ≥ 1 measureable lesions according to Response Evaluation Criteria Solid Tumors 1.0 criteria;...
3510 Background: It’s presented the results of a phase III trial short-term radiotherapy (SCRT) combined with chemotherapy versus long-term chemoradiotherapy (LCRT) in patients locally advanced rectal cancer (LARC). Methods: Patients distal or middle third, T3-T4 and/or N+ adenocarcinomas diagnosed by MRI, were randomly assigned to experimental group control group. In group, received SCRT (25 Gy / 5 fractions days), followed four courses CAPOX. LCRT (50 25 35 days concurrent capecitabine)....
Abstract Background Helicobacter pylori ( H. ) can disrupt the tight junctions between gastric epithelial cells and penetrate intercellular spaces acting on cells, normal fibroblasts (NFs), cancer-associated (CAFs), but their interaction in cancer tumorigenesis progression remains unclear. Methods Primary CAFs NFs were isolated from paired tissues adjacent identified by immunofluorescence staining western blot analysis for FSP-1, α-SMA, FAP, vimentin expression. RNA-sequencing was used to...
Objective: To investigate the relationship between telomerase activity (TA) and matrix metallo proteinases 2 (MMP-2) on malignant behavior prognosis predictable value in gastric cancer. Methods: Telomerase MMP-2 protein expressions w
Objective: A retrospective analysis was conducted to investigate the effect of preoperative prognostic nutritional index (PNI) on severity toxic side effects radiochemotherapy and survival prognosis patients with gastric cancer guide clinical support for cancer. Methods: Data 191 in Department Gastrointestinal Surgery Guizhou Cancer Hospital Affiliated Medical University between January 2008 December 2018 were analyzed retrospectively. Patients allocated high PNI group (with ≥ 47.7) low <...
RNA-binding motif protein 39 (RBM39) is a well-known involved in tumorigenesis; however, its role hepatocellular carcinoma (HCC) remains unclear. The aim of this study was to investigate the RBM39 HCC.
Retraction: ‘ Ailanthone exerts an antitumor function on the development of human lung cancer by upregulating microRNA‐195 ’, Shizhen Hou, Ziming Cheng, Wenling Wang, Xiangdong Yubing Wu, J Cell Biochem. 2019; 10444‐10451: The above article, published online 19 December 2018 in Wiley Online Library ( https://onlinelibrary.wiley.com/doi/full/10.1002/jcb.28329 ), has been retracted agreement between journal's Editor Chief, Prof. Dr. Christian Behl, and Periodicals LLC. retraction agreed...
Gastric cancer ranks high in terms of morbidity and mortality worldwide. Multimodal therapy is therefore essential for locally advanced gastric cancer. Recent studies have demonstrated that both perioperative chemotherapy neoadjuvant chemoradiotherapy can improve the prognosis patients. However, completion rate after surgery remains low, which may affect survival. Thus, identifying best way to combine radiotherapy, important. The aim this study was explore toxicity efficacy total modality...
Helicobacter pylori (H. pylori) is a spiral-shaped Gram-negative bacterium that causes the most common chronic infection in human stomach. Approximately 1%-3% of infected individuals develop gastric cancer. However, mechanisms by which H. induces cancer are not completely understood. The available evidence indicates strong link between virulence factor pylori, cytotoxin-associated gene A (CagA), and To further characterize virulence, we established three cell lines infecting SGC-7901 AGS...
Endometrial carcinoma (EC) is a common type of uterine cancer in developed countries, originating from the epithelium. The incidence rate EC Taiwan has doubled 2005. Cancer stem cells (CSCs) are subpopulation that have high tumorigenicity and play crucial role malignant processes cancer. Targeting molecules associated with CSCs essential for effective treatments. This study delves into Exosome component 5 (EXOSC5) EC. Data Genome Atlas suggests correlation between EXOSC5 mRNA expression...
To evaluate the impact of primary tumor radiotherapy on survival in patients with unresectable metastatic rectal or rectosigmoid cancer. From September 2008 to 2017, 350 cancer were retrospectively reviewed our center. All received at least 4 cycles chemotherapy and divided into two groups according whether they radiotherapy. A total 163 radiotherapy, median radiation dose was 56.69 Gy (50.4-60). Survival curves estimated Kaplan-Meier method roughly compare between groups. Subsequently,...
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in world with high morbidity and mortality. Identifying an effective marker for predicting prognosis therapeutic response extremely meaningful. Angiogenesis-related genes (ARGs) play important roles tumor progression immune-suppressive microenvironment formation.The differential expressed ARGs associated HCC were identified TCGA dataset. Univariate Cox least absolute shrinkage selection operator (LASSO) regression...
<h3>Importance</h3> Several studies have explored the efficacy and toxic effects of concurrent 5-fluorouracil (5-FU)– or capecitabine-based chemoradiotherapy (CRT) with without oxaliplatin in neoadjuvant setting. Addition to 5-FU capecitabine elicited similar outcomes but significantly increased effects; however, there is a need for randomized clinical trials comparing 2 CRT regimens patients receiving adjuvant <h3>Objective</h3> To explore combined postoperative radiotherapy (RT)...