A5030945806- Hearing, Cochlea, Tinnitus, Genetics
- Vestibular and auditory disorders
- Autism Spectrum Disorder Research
- Automotive and Human Injury Biomechanics
- Cellular Mechanics and Interactions
- Congenital heart defects research
- PI3K/AKT/mTOR signaling in cancer
- Elasticity and Material Modeling
- Tuberous Sclerosis Complex Research
- Neuroscience of respiration and sleep
- Polyamine Metabolism and Applications
- Tissue Engineering and Regenerative Medicine
The University of Texas Southwestern Medical Center
2017-2020
Southwestern Medical Center
2020
Boston Children's Hospital
2016-2018
Harvard University
2016-2018
To design and engineer materials inspired by the properties of brain, whether for mechanical simulants or tissue regeneration studies, brain itself must be well characterized at various length time scales. Like many biological tissues, exhibits a complex, hierarchical structure. However, in contrast to most other is very low stiffness, with Young's elastic moduli E on order 100s Pa. This stiffness can present challenges experimental characterization key properties. Here, we demonstrate...
Causes of autism spectrum disorders (ASD) are understood poorly, making diagnosis and treatment challenging. While many studies have investigated the biochemical genetic aspects ASD, whether how mechanical characteristics autistic brain can modulate neuronal connectivity cognition in ASD unknown. Previously, it has been shown that brains characterized by abnormal white matter disorganized connectivity; we hypothesized these significant cellular-level structural changes may translate to...