- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Clinical Nutrition and Gastroenterology
- Family and Patient Care in Intensive Care Units
- Electrolyte and hormonal disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Thermal Regulation in Medicine
- Anesthesia and Neurotoxicity Research
- Sepsis Diagnosis and Treatment
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac and Coronary Surgery Techniques
- Parathyroid Disorders and Treatments
- Nosocomial Infections in ICU
- Dermatological and Skeletal Disorders
- Diphtheria, Corynebacterium, and Tetanus
- Music Therapy and Health
- Metabolism and Genetic Disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
- Migraine and Headache Studies
- EEG and Brain-Computer Interfaces
- Acupuncture Treatment Research Studies
Yonsei University
2009-2022
Gangnam Severance Hospital
2014-2018
Yonsei University Health System
2018
University of Freiburg
2018
Severance Hospital
2011
There is a growing interest in research aimed at better understanding the disease status or predicting prognosis of patients with simple blood tests associated systemic inflammation. The neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte (LMR), platelet-lymphocyte (PLR), and mean platelet volume (MPV) can be used as factors to determine various clinical situations. However, reference values for these attributes based on large, healthy populations have yet determined. From January 2014...
Diaphragmatic dysfunction is a major factor in the etiology of postoperative pulmonary complications after upper abdominal surgery. M-mode ultrasonography now an accepted qualitative method assessing diaphragmatic motion normal and pathological conditions. In this study, we evaluated whether inspiratory amplitude (DIA) as measured by sonography can be predictor dysfunction.A prospective, single-center, single-unit, observational study was performed 35 ASA physical status I II nonsmoking...
Delirium is an important syndrome found in patients the intensive care unit (ICU), however, it usually under-recognized during treatment. This study was performed to investigate whether delirious can be successfully distinguished from non-delirious by using heart rate variability (HRV) and machine learning.Electrocardiography data of 140 acquired daily ICU care, HRV were analyzed. Delirium, including its type, severity, etiologies, evaluated trained psychiatrists. various learning algorithms...
Abstract Background: Vitrectomy under general anesthesia is considered as a candidate for ambulatory surgery. An anesthetic method with high quality of postoperative recovery should be selected successful We thus compared on the day vitrectomy using Quality Recovery (QoR)-40 questionnaire between propofol total intravenous (propofol group) and desflurane inhalation (desflurane 2 representative methods. Methods: Eighty-four patients (20–80 years old) undergoing elective were randomized into...
Delirium is an important syndrome in intensive care unit (ICU) patients, however, its characteristics are still unclear. Many evidences showed that this can be related to the autonomic instability. In study, we aimed investigate possible alterations of nervous system (ANS) delirium patients ICU. Electrocardiography (ECG) every ICU patient was measured during routine daily care, and data were gathered evaluate heart rate variability (HRV). HRV total 60 analyzed time, frequency non-linear...
Abstract Although integrated home internet of things (IoT) services can be beneficial, especially for vulnerable older adults, the hurdle usability hinders implementation technology. This study aimed to evaluate practical IoT in by frailty status, and determine potential obstacles. From August 2019 July 2020, we randomly selected 20 adults (prefrailty group [ n = 11], 9]) who had already been identified as needing a community-based prospective cohort study, Aging Study Pyeongchang Rural...
Greater occipital nerve block is used in the treatment of headaches and neuralgia area. We evaluated efficacy ultrasonic doppler flowmeter-guided patients experiencing headache region a randomized, prospective, placebo-controlled study.Twenty-six patients, aged 18 to 70, with region, were included study. Patients received greater performed either under flowmeter guidance using 1% lidocaine or traditional method. Sensory examination findings evaluated.The complete rate blockade group was...
Background: Early recognition of the signs and symptoms clinical deterioration could diminish incidence cardiopulmonary arrest.The present study investigates outcomes with respect to arrest rates in institutions without rapid response systems (RRSs) current level rate tertiary hospitals.Methods: This was a retrospective based on data from 14 hospitals.Cardiopulmonary resuscitation (CPR) reports were obtained each hospital include number events adult patients general ward, annual admission...
The long-term outcomes of patients discharged from the hospital after successful care in intensive unit (ICU) are not briskly evaluated Korea. aim this study was to assess mortality treated ICU and alive identify predictive factors mortality.In 3,679 adult between 2006 2011, 1-year rate (primary outcome measure) investigated. Various were entered into multivariate analysis independent mortality, including sex, age, severity illness (APACHE II score), mechanical ventilation, malignancy,...
Postoperative nausea and vomiting (PONV) is a common problem in patients recovering from anesthesia surgery. P6 point the acupressure for prevention of postoperative vomiting. We evaluated efficacy at 94 undergoing thyroidectomy randomized, prospective placebo-controlled study.Ninety-four female patients, aged 18 to 60, scheduled elective thyroidectomy, were randomized have either placebo band or (Sea-Band(R) UK Ltd., Leicestershire, England, UK) applied both hands before induction...
Background: Malnutrition is common in hospitalized patients, especially critically ill patients and affects their mortality morbidity. However, the correlation between malnutrition poor outcome not fully understood. Our hypothesis that nutritional effect on patient’s prognosis would differ depending severity of disease. Methods: 3,758 admitted to intensive care unit (ICU) were observed retrospectively. Patients divided into well, moderate severe groups, according status as assessed by serum...
Upon inducting general anesthesia in the operating room, we have observed a prompt increase bispectral index (BIS) after intravenous injection of suxamethonium. We hypothesized that cause this BIS is muscle hyperactivity owing to fasciculation. However, no reports been published regarding abrupt upon induction by To investigate degree change patients receiving with suxamethonium, performed prospective observational study 63 participants who underwent closed reduction for nasal bone fracture....
We aimed to establish the propofol effect-site concentration (Ce) for appropriate sedation by pharmacodynamic analysis and determine Ce during occurrence of sedation-related side effects in pediatric patients undergoing brain magnetic resonance imaging (MRI).In 50 scheduled MRI, was induced with 2.0 mg/kg propofol; additional doses were 0.5-1 mg/kg. Propofol simulated inputting administration profiles into a compartmental model (Choi model). The relationship between probabilities recovery...
Light chain systemic amyloidosis is rare but may accompany laryngeal or pulmonary involvement, which increase the risk in airway management. We present a case of patient planned for resection cervical epidural mass. The had face and neck ecchymoses purpuras with an unknown cause. Mask ventilation intubation were successful, operation was cancelled to evaluate bleeding from facial skin lesions. A diagnosis light prompted evaluation involvement other organs treatment. This shows importance...
IntroductIonDelirium management is still a very complex problem, and therefore the range of pharmacological treatment limited effects nonpharmacological interventions are controversial [1,2].Antipsychotic drugs help to manage some specific symptoms hyperactive delirium, known as intensive care unit (ICU) psychosis [3].Anxiety pain can cause while medications used relieve these two also induce delirium [4,5].Therefore, it difficult maintain proper balance.The treatments have been controversial.
We present a molecular dynamics simulation study of alkali metal cation transport through the double‐helical and head‐to‐head conformers gramicidin ion channel. Our approach is based on thermodynamic integration network, which consists sequence reactions, absolute free energies solvation cycles alchemical transmutations ions. In this manner, we can reliably estimate their statistical errors via least‐squares method without imposing external forces system. Within double helical channel, find...
Background: Although head of bed (HOB) elevation is an important strategy to prevent ventilator associated pneumonia (VAP), some observational studies have reported that the application semi-recumbent position was lower in patients receiving mechanical support.We performed this study assess effect implementation HOB protocol intensive care unit (ICU) on clinical and nutritional outcomes.Methods: We developed a including flow chart determine whether newly admitted ICU could be elevated.We...
A 30-year-old female patient, 18 weeks gestational age, with no prior medical history was admitted to hospital complaining severe right upper quadrant pain. The patient intensive care unit (ICU) after emergency surgery treat intraperitoneal hemorrhage caused by rupture of liver hematoma. Despite the absence high blood pressure, diagnosed hemolysis, elevated enzymes, and low platelet count (HELLP) syndrome on basis abnormal levels aspartate aminotransferase/alanine aminotransferase, lactate...
Background: Hydroxyethyl starch (HES) effectively restores plasma volume and thereby enhances microcirculation tissue oxygenation at the expense of coagulation impairment.These effects are related to molecular weight, substitution C2:C6 ratio.But, most studies regarding impairment in cardiac surgeries were performed patients undergoing cardiopulmonary bypass which significantly causes derangements.Therefore, we have evaluated 2 different HES solutions on postoperative bleeding off-pump...