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Savana M. Green

ORCID: 0000-0003-4212-5314
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About
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A5082801985
Research Areas
  • Plant Virus Research Studies
  • Legume Nitrogen Fixing Symbiosis
  • Cellular transport and secretion
  • Fungal and yeast genetics research
  • Plant-Microbe Interactions and Immunity

Texas A&M University
 2022-2023

 Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity
OPENALEX - Publications 
Xiaoru Chen Lokendra Poudel Zebin Hong Philipp Johnen Sachin Katti and 8 more Ashutosh Tripathi Aaron H. Nile Savana M. Green Danish Khan Gabriel Schaaf F. Bono Vytas A. Bankaitis Tatyana I. Igumenova

10.1016/j.jbc.2022.102861 article EN cc-by-nc-nd Journal of Biological Chemistry 2023-01-02
 Mechanisms by Which Small Molecule Inhibitors Arrest Sec14 Phosphatidylinositol Transfer Protein Activity
OPENALEX - Publications 
Xiaoru Chen Lokendra Poudel Zebin Hong Philipp Johnen Sachin Katti and 7 more Ashutosh Tripathi Aaron H. Nile Savana M. Green Gabriel Schaaf F. Bono Vytas A. Bankaitis Tatyana I. Igumenova

Abstract Phosphatidylinositol transfer proteins (PITPs) promote phosphoinositide signaling by enhancing phosphatidylinositol (PtdIns) 4-OH kinase activities in producing pools of PtdIns-4-phosphate. As such, PITPs are key regulators lipid eukaryotic cells. While the PITP phospholipid exchange cycle is engine that stimulates PtdIns activity, protein and dynamics associated with this critical process not understood. Herein, we use an integrative structural approach takes advantage small...

10.1101/2022.08.01.502361 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-08-02
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