A5101444116- Virology and Viral Diseases
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Virus-based gene therapy research
- Viral Infections and Vectors
- Crystallization and Solubility Studies
- Animal Virus Infections Studies
- Enzyme Production and Characterization
- X-ray Diffraction in Crystallography
- Mosquito-borne diseases and control
- Microbial bioremediation and biosurfactants
- Heavy metals in environment
- Metal complexes synthesis and properties
- Coastal wetland ecosystem dynamics
- Nanoparticles: synthesis and applications
- Bacteriophages and microbial interactions
- Methane Hydrates and Related Phenomena
- Nanoparticle-Based Drug Delivery
- Advanced Cellulose Research Studies
- Plant Virus Research Studies
- Graphene and Nanomaterials Applications
- Arsenic contamination and mitigation
- Polysaccharides and Plant Cell Walls
- MicroRNA in disease regulation
- RNA and protein synthesis mechanisms
University of Calcutta
2010-2023
Techno India Group (India)
2021-2022
Freeman Hospital
2011
Centre For Human Genetics
2007
University of California, San Diego
2007
Newcastle University
2007
Indian Institute of Science Bangalore
2004
Bose Institute
1999-2004
Indian Institute of Management Calcutta
2004
National Institute of Cholera and Enteric Diseases
2004
Abstract Background Sundarban is the world's largest coastal sediment comprising of mangrove forest which covers about one million hectares in south-eastern parts India and southern Bangladesh. The microbial diversity this largely unknown till date. In present study an attempt has been made to understand using a cultivation-independent molecular approach. Results Two 16 S rRNA gene libraries were constructed partial sequencing selected clones was carried out identify bacterial strains...
Non- small- cell lung cancer (NSCLC) is one of the most leading causes cancer-related deaths worldwide. Paclitaxel based combination therapies have long been used as a standard treatment in aggressive NSCLCs. But paclitaxel resistance has emerged major clinical problem combating non-small-cell and autophagy important mechanisms involved this phenomenon. In study, we microRNA (miRNA) arrays to screen differentially expressed miRNAs between sensitive cells A549 its paclitaxel-resistant variant...
Microbial remediation of oil polluted habitats remains one the foremost methods for restoration petroleum hydrocarbon contaminated environments. The development effective bioremediation strategies however, require an extensive understanding resident microbiome these habitats. Recent developments such as high-throughput sequencing has greatly facilitated advancement microbial ecological studies in However, interpretation biological characteristics from large datasets remain a considerable...
Abstract Tumor relapse in triple negative breast cancer patients has been implicated to chemoresistant stem cells (CSCs), which under favorable conditions culminate tumor re-formation and metastasis. Hence, eradication of CSCs during systemic chemotherapy is imperative. were sorted using immuno-phenotyping aldefluor assay. Gene expression profiling normal from chemo-treated carried out. Silencing SOX2 was achieved by siRNA method. Mammosphere culture wound healing assays out assess efficacy...
Macrophages play a critical role in innate immunity. Differentiation Ags present on macrophages such as CD14 orchestrate the first line of defense against infection. The basal/homeostatic signaling scheme that keeps thus groomed for immune functions remains unresolved. Wnt5a-Fz5 being primordial event during cell differentiation, we examined involvement maintenance functions. In this study, demonstrate ensue at least partly through homeostatic Wnt5a-Fz5-NF-κB (p65) circuit, which is Rac1...
The global knowledge of microbial diversity and function in Sundarbans ecosystem is still scarce, despite advancement understanding the diversity. In present study, we have analyzed distribution bacteria tropical mangrove sediments using 16S rRNA gene amplicon sequencing. Metagenome comprised 1,53,926 sequences with 108.8 Mbp data 55 ± 2% G + C content. sequence are available at NCBI under Bioproject database accession no. PRJNA245459. Bacterial community metagenome were by MG-RAST software...
Mangroves are among the most diverse and productive coastal ecosystems in tropical subtropical regions. Environmental conditions particular to this biome make mangroves hotspots for microbial diversity, resident communities play essential roles maintenance of ecosystem. Recently, there has been increasing interest understand composition contribution microorganisms mangroves. In present study, we have analyzed diversity distribution archaea mangrove sediments Sundarbans using 16S rRNA gene...
A new dinuclear nickel(II) complex, [Ni2(LH2)(H2O)2(OH)(NO3)](NO3)3 (1), of an "end-off" compartmental ligand 2,6-bis(N-ethylpiperazine-iminomethyl)-4-methyl-phenolato, has been synthesized and structurally characterized. The X-ray single crystal structure analysis shows that the piperazine moieties assume expected chair conformation are protonated. complex 1 exhibits versatile catalytic activities biological significance, viz. catecholase, phosphatase, DNA cleavage activities, etc....
Three mononuclear organotin(IV) complexes supported by Schiff bases have been synthesized. The [(C 6 H 5 ) 2 Sn(L)] ( 1 ), [( t ‐Bu) and Sn(L')] 3 (L, L' = deprotonated bases) were obtained in good yield the reaction of L or L′ with corresponding diorganotin dichlorides respectively. All newly synthesized characterized means FT‐IR spectroscopy, elemental analysis multinuclear H, 13 C 119 Sn) NMR spectroscopy. In addition, single crystal X‐ray diffraction analyses employed to establish solid...