A5035224942- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Retinal and Macular Surgery
- Infectious Encephalopathies and Encephalitis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Gender Diversity and Inequality
- Facial Rejuvenation and Surgery Techniques
- Paraoxonase enzyme and polymorphisms
- Cancer and Skin Lesions
- Ocular Oncology and Treatments
- Reproductive Biology and Fertility
- Pregnancy and preeclampsia studies
- Healthcare Systems and Reforms
- Ophthalmology and Eye Disorders
- Neonatal and fetal brain pathology
- Neurological Complications and Syndromes
- Complement system in diseases
- Retinal and Optic Conditions
- Bacterial Infections and Vaccines
- Peripheral Artery Disease Management
- Renal Diseases and Glomerulopathies
University of Michigan
2020-2025
W.K. Kellogg Foundation
2020-2024
Harvard University
2018-2019
Massachusetts Eye and Ear Infirmary
2018
University of Southern California
2018
Wills Eye Hospital
2018
Retinal detachment has previously been reported in association with topical miotic use for the treatment of glaucoma. Pilocarpine hydrochloride 1.25% was recently approved by Food and Drug Administration presbyopia, no reports associated retinal detachments clinical trial data.Case report.Two novel cases unilateral occurring within 10 days initiation pilocarpine presbyopia were described. The patients pseudophakic men their 60s or 70s preexisting risk factors, such as high myopia, lattice...
To assess whether metformin is associated with dry age-related macular degeneration (dAMD) development.In this retrospective cohort study, patients enrolled in a nationwide U.S. medical insurance claims database from 2002 to 2016 were included if they had diabetes mellitus, ⩾55 years old, and for ⩾2 without prior AMD diagnosis. The primary exposure was use analyzed as either active or cumulative dosage over the study period. A time updating Cox proportional hazard regression used estimate...
To assess the outcomes of resident-performed cataract surgeries with iris challenges and to compare these similar performed by attending surgeons.Massachusetts Eye Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.Retrospective chart review.All cases extraction phacoemulsification intraocular lens implantation, comprehensive ophthalmologists between January 1 December 31, 2014, were reviewed. Cases preoperative or intraoperative miosis, prolapse, floppy syndrome, included for...
Basal cell carcinoma (BCC) is a common skin cancer caused by deregulated hedgehog signaling. BCC often curable surgically; however, for orbital and periocular BCCs (opBCC), surgical excision may put visual function at risk. Our recent clinical trial highlighted the utility of vismodegib preserving organs in opBCC patients: 67% patients displayed complete response histologically. However, further analysis samples uncovered keratin positive, active (Gli1 positive), proliferative micro-tumors....
Objective To identify factors that contribute to missed cataract surgery follow-up visits, with an emphasis on socioeconomic and demographic factors. Methods In this retrospective cohort study, patients who underwent extraction by phacoemulsification at Massachusetts Eye Ear between 1 January 31 December 2014 were reviewed. Second eye cases, remote international patients, foreign insurance combined cases excluded. Results A total of 1931 reviewed 1089 corresponding 3267 scheduled...
Abstract Background Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia and precursor to multiple myeloma. It has known ocular manifestations, but not previously been shown have an association with autoimmune retinopathy. Case presentation A 57 year-old female presented 1 year progressive, bilateral, peripheral vision loss, photopsias, nyctalopia. Her fundus examination extensive ancillary testing were concerning for hereditary versus The patient was found...
Purpose: To determine the efficacy of a frontalis muscle flap eyelid reanimation technique for correction severe congenital ptosis and associated amblyopia in infants. Methods: The authors performed retrospective chart review patients 12 months age or younger with unilateral bilateral deemed at high risk due to visual deprivation. Following repair via technique, primary outcomes postoperative position reversal were assessed. Results: Seventeen eyes participants included study. Seven these...
Abstract: A 3-month-old male infant appeared on multiple clinical examinations to have acutely developed bilateral retrogeniculate blindness. Electroencephalography showed focal status epilepticus confined the left posterior cerebral hemisphere. MRI demonstrated restricted diffusion in domain of artery consistent with acute stroke. Notably, extended across midline splenium corpus callosum. This splenial sign may be imaging correlate diaschisis, a well-described phenomenon which patients new...
Purpose: To describe a novel case of focal exudative retinal detachment, choroidal effusion, and acute angle closure in preeclampsia. Methods: A report is presented. Results: 37-year-old woman at 38 weeks gestation presented with 2 progressive blurred vision the left eye. She had visual acuity (VA) 20/800 an intraocular pressure (IOP) 26 mm Hg eye (compared 17 right eye). Examination showed subretinal fluid posterior pole, ciliochoroidal without pathology was found to have hypertension...
Hintergrund: Monoklonale Gammopathie unklarer Signifikanz (MGUS) ist eine Plasmazelldyskrasie und Vorstufe des Multiplen Myeloms. Okuläre Manifestationen sind bekannt, bislang wurde jedoch noch kein Zusammenhang mit einer Autoimmun-Retinopathie nachgewiesen. Fallvorstellung: Eine 57-jährige Frau stellte sich seit einem Jahr bestehendem progressiven, beidseitigen, peripheren Verlust Sehvermögens, Photopsien Nachtblindheit vor. Die Augenhintergrunduntersuchung umfassende ergänzende Tests...
Purpose/Aim: To assess whether ocular antihypertensives are associated with the development and progression of age-related macular degeneration (AMD).Materials Methods: This retrospective, observational cohort study using healthcare claims data from a U.S. nationwide managed-care network between January 1, 2006 December 31, 2016, included enrollees ≥40 years old primary open-angle glaucoma or without diagnosis nonexudative AMD at index date. Hazard ratios (HR) for developing progressing to...