A5040461700- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Cardiac electrophysiology and arrhythmias
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Cardiac pacing and defibrillation studies
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- Obstructive Sleep Apnea Research
- Cardiovascular and Diving-Related Complications
- Healthcare Systems and Public Health
- Heart Failure Treatment and Management
- Hormonal Regulation and Hypertension
- Cancer Immunotherapy and Biomarkers
- Aortic Disease and Treatment Approaches
- Heart Rate Variability and Autonomic Control
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Eosinophilic Esophagitis
Yokohama City University Medical Center
2020-2025
Yokohama City University
2020-2025
National Sagamihara Hospital
2017
Background: In 2023, Japan had the highest proportion of elderly in world, with one 10 individuals aged ≥80 years. Consequently, number patients cardiovascular diseases is increasing. Older often have comorbidities such as frailty, sarcopenia, and cognitive decline that leads to a decreased quality life (QOL). We analyzed effects outpatient cardiac rehabilitation (OCR) disease. Methods: The comprehensive OCR been provided by multidisciplinary team. data from 49 diseases, years, who received...
Introduction: Immune checkpoint inhibitors are the mainstay of treatment for unresectable or metastatic renal cell carcinoma (RCC). However, they can cause immune-related adverse events (irAEs), and management these irAEs is critical. The combination myasthenia gravis, myositis myocarditis, which irAEs, rare, it has not been reported to occur with avelumab. This report aimed present a rare case RCC metastasis that developed during avelumab axitinib therapy. Case Presentation: A 76-year-old...
Chronic obstructive pulmonary disease (COPD) is one of the most common comorbidities in patients with chronic heart failure (CHF). A growing number are suffering from both COPD and CHF, these conditions worsen each other. Inhaled bronchodilator therapy long-acting muscarinic antagonist (LAMA) β2-agonist (LABA) combination currently mainstay treatment for COPD. However, effect LAMA/LABA on HF remains unknown. The COPD-HF trial a multicenter, double-arm, open-label, exploratory,...
In patients with ST-segment elevation myocardial infarction (STEMI), predicting left ventricular (LV) remodelling (LVR) and prognosis is important. We explored the clinical usefulness of three-dimensional (3D) speckle-tracking echocardiography to predict LVR in STEMI.
Three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) is associated with left ventricular (LV) remodeling and 1-year prognosis. This study investigated the clinical significance of 3D-STE in predicting long-term prognosis patients STEMI.Methods Results:A total 270 (mean age 64.6 years) first-time STEMI treated reperfusion therapy were enrolled. At 24 h admission, standard 2D 3D full-volume imaging performed, 2D-STE calculated....
Background: The role of left atrial (LA) function in the long-term prognosis ST-elevation acute myocardial infarction (STEMI) is still unclear.
A delayed and recurrent complete atrioventricular block (CAVB) is a life-threatening complication of transcatheter aortic valve replacement (TAVR). Post-TAVR evaluation may be important in predicting CAVB requiring permanent pacemaker implantation (PPI). The impact new-onset right bundle-branch (RBBB) after TAVR on PPI remains unknown.
The role of left ventricular (LV) mechanical dispersion estimated after an ST elevation acute myocardial infarction (STEMI) remains unclear.The study participants were 208 consecutive patients (152 men, age = 72 years) presenting with STEMI for the first time who underwent primary percutaneous coronary intervention (PCI) within 12 h onset. Within 48 PCI (mean 24 h), 2D and 3D speckle-tracking echocardiography performed. global longitudinal strain (GLS) was calculated using (3D-GLS) (2D-GLS)...
Early and intensive low-density lipoprotein (LDL-C)-lowering therapy plays important roles in secondary prevention of acute coronary syndrome (ACS), but the treatment period for further clinical benefit remains undefined. This single-center, retrospective study explored LDL-C trajectory after ACS its associations with subsequent cardiovascular events (CVE).
Two-dimensional (2D) and three-dimensional (3D) speckle tracking echocardiography (STE) after ST-elevation acute myocardial infarction (STEMI) can predict the prognosis. This study investigated clinical significance of a serial 3D-STE prognosis onset STEMI.
This study aimed to investigate the effect of glycemic variability (GV), determined using a continuous glucose monitoring system (CGMS), on left ventricular reverse remodeling (LVRR) after ST-segment elevation myocardial infarction (STEMI).A total 201 consecutive patients with STEMI who underwent reperfusion therapy within 12 h onset were enrolled. GV was measured CGMS and as mean amplitude excursion (MAGE). Left volumetric parameters cardiac magnetic resonance imaging (CMRI). LVRR defined...
Background: Rapidly progressive, extensive myocardial injury/infarction (RPEMI) beyond the concept of wave-front phenomenon can be observed even when achieving timely reperfusion; however, pathogenesis RPEMI remains unknown. This retrospective study investigated clinical and lesion characteristics RPEMI, focusing on culprit-lesion morphology (CLM). Methods: Among patients with anterior-wall ST-segment elevation infarction due to proximal left anterior descending artery lesions who had...
Background:The early mitral inflow velocity to diastolic ratio (E/e′) and electrocardiogram (ECG) determination of QRS score are useful for risk stratification in patients with ST-elevation myocardial infarction (STEMI).
Background:The significance of late diastolic velocity (a′) obtained by tissue Doppler imaging (TDI), which reveals atrial function, in ST-elevation myocardial infarction (STEMI) remains unclear. This study evaluated the association TDI parameters determined either immediately or 2 weeks after percutaneous coronary intervention (PCI) with long-term outcomes.
The aim of this study was to create a risk scoring model differentiate obstructive coronary artery (CA) from CA spasm in the etioology acute syndrome (ACS).
Abstract Introduction While prevention of major cardiovascular adverse events (MACE) is important in the management patients after percutaneous coronary intervention (PCI), risk stratification MACE remains a significant challenge with increasingly diverse and complex patient backgrounds. In response to that, this retrospective observational study aimed explore whether machine learning (ML) methods can predict future PCI using variety features extracted from electronic medical records (EMRs)....
Background Contradictions between management modalities of type A acute aortic dissection (TAAAD) and ST-elevation-myocardial infarction (STEMI) may result in clinical catastrophe. Therefore, we aimed to explore which 2-dimensional echocardiography (2DE) findings are optimal for differentiating TAAAD from STEMI. Methods Results This study included 340 patients with STEMI who underwent 2DE the emergency department 2012 2021. The proximal ascending aorta (PAA) diameter other echocardiographic...
Background: We retrospectively investigated the effects of severity and classification sleep-disordered breathing (SDB) on left ventricular (LV) function in patients with ST-segment elevation myocardial infarction (STEMI). Methods: A total 115 STEMIs underwent a sleep study using multichannel frontopolar electroencephalography recording device (Sleep Profiler) one week after STEMI onset. evaluated LV global longitudinal strain (LV-GLS) two-dimensional echocardiography at seven months....
Abstract Background A QRS scoring system by 12-lead electrocardiography (ECG) is a quick and simple method to evaluate degree extension of myocardial infarction. Previous studies have shown that high scores (≥5) at hospitalization (before reperfusion) related impaired reperfusion during percutaneous coronary intervention (PCI) subsequent poor prognosis in patients with ST-segment elevation infarction (STEMI) (Figure 1). However, the pathogenesis associated factors remain poorly defined....
Abstract Background Transthyretin cardiac amyloidosis (ATTR-CA) appears to be prevalent in aortic stenosis (AS). The coexistence of ATTR-CA and severe AS is associated with an increased risk hospitalization for heart failure after transcatheter valve implantation (TAVI). identification great clinical importance. In this study, we investigated the diagnostic value computed tomography-derived myocardial extracellular volume (CT-ECV) diagnosis biopsy-proven ATTR-CA. Methods From December 2022...