A5007401814- Breast Lesions and Carcinomas
- Breast Cancer Treatment Studies
- BRCA gene mutations in cancer
- Cancer and Skin Lesions
- Genomic variations and chromosomal abnormalities
- Thyroid Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Nutrition, Genetics, and Disease
- Global Cancer Incidence and Screening
- Garlic and Onion Studies
- Cancer Risks and Factors
- Digital Radiography and Breast Imaging
- Cervical Cancer and HPV Research
- Ovarian cancer diagnosis and treatment
- Salivary Gland Tumors Diagnosis and Treatment
- MRI in cancer diagnosis
- DNA Repair Mechanisms
- Nutrition, Health and Food Behavior
- Cardiovascular Health and Risk Factors
- Genetic Associations and Epidemiology
- Male Breast Health Studies
- Phytoestrogen effects and research
- Healthcare Systems and Public Health
- Parasite Biology and Host Interactions
Seoul National University
2009-2025
Seoul National University Hospital
2025
Seoul National University Bundang Hospital
2024
Hanyang University
2024
CHA University
2006-2023
CHA Gangnam Medical Center
2009-2023
Boramae Medical Center
2017
New Generation University College
2012
National University College
2012
Samsung Medical Center
2000
No nationwide epidemiological study evaluating the prevalence of subclinical and overt forms hypothyroidism hyperthyroidism has yet been conducted in Korea. This aimed to evaluate reference range serum thyroid stimulating hormone (TSH) national dysfunctions Korea.Nation-wide cross-sectional data were analyzed from a representative sample civilian, non-institutionalized Korean population (n=6,564) who underwent blood testing for function anti-thyroid peroxidase antibody (TPOAb) as part Korea...
BackgroundFive risk factors account for approximately 50% of the global burden cardiovascular disease. How presence or absence classic affects lifetime estimates disease and death from any cause remains unclear.MethodsWe harmonized individual-level data 2,078,948 participants across 133 cohorts, 39 countries, 6 continents. Lifetime was estimated up to 90 years age according arterial hypertension, hyperlipidemia, underweight overweight obesity, diabetes, smoking at 50 age. Differences in life...
The gold standard for breast biopsy procedures is currently an open excision of the suspected lesion. However, excisional inevitably makes a scar. cost and morbidity associated with this procedure has prompted many physicians to evaluate less invasive, alternative procedures. More recently, image-guided percutaneous core-needle become frequently used method diagnosing palpable non-palpable lesions. Although sensitivity rates are high, it disadvantage histological underestimation, which...
A pilot clonorchiasis control project was implemented to evaluate the efficacies of various chemotherapy strategies on prevalence, incidence and re-infection in Heilongjiang Province, China.Seven intervention groups (14,139 residents, about 2000 each group) heavily or moderately endemic areas were subjected repeated praziquantel administration from 2001 2004. In selective groups, residents examined for fecal eggs, those who tested positive treated with three doses 25 mg/kg at...
Purpose We evaluated the performance of Gail model for a Korean population and developed breast cancer risk assessment tool (KoBCRAT) based upon equations predicting risk. Methods Using 3,789 sets cases controls, factors among Koreans were identified. Individual probabilities projected using Gail's hazard data. compared 5-year lifetime produced modified which applied incidence mortality data parameter estimators from original with those KoBCRAT. validated KoBCRAT on expected/observed area...
Abstract A 37‐year‐old woman presented with breast pain after augmentation utilizing autologous fat obtained by liposuction. Mammography and sonography demonstrated necrosis in the right a solid inflammatory mass left breast. The diagnoses were confirmed biopsy. © 2004 Wiley Periodicals, Inc. J Clin Ultrasound 32:299–301,
The aim of this study is to summarize cancer risk among patients with clinical indications immunosuppressive and antineoplastic drugs in Korea, which are pharmaceuticals defined as group 1 by International Agency for Research on Cancer (IARC). We conducted a nationwide population-based retrospective cohort using the Korean National Health Insurance Service (NHIS) claims data from 2002 2018. Patients 2017 were selected baseline population, followed up until Cox proportional hazards regression...
Background BRCA1 and BRCA2 ( BRCA1/2 ) variants classified ambiguously as of uncertain significance (VUS) are a major challenge for clinical genetic testing in breast cancer; their relevance to the cancer risk is unclear association with response specific -targeted agents uncertain. To minimise proportion VUS , we performed multifactorial likelihood analysis validated this method using an independent cohort patients cancer. Methods We used data set 2115 from nationwide multicentre...
Large genomic rearrangements (LGRs) in the BRCA1/2 genes are frequently observed breast cancer patients who negative for small mutations. Here, we examined 221 familial from 37 hospitals to estimate contribution of LGRs, a nationwide context, development cancer.Direct sequencing or mutation scanning followed by direct was performed screen mutation-negative were screened presence LGRs using multiple ligation-dependent probe amplification (MLPA) assay.Using combined strategy detect mutations...
Percutaneous removal of benign breast tumors using ultrasound-guided vacuum-assisted biopsy (VABB) has been recently regarded as a feasible and safe method without serious complications. The aim this study was to evaluate the efficacy safety VABB in treatment phyllodes tumors, identify whether or not surgical re-excision is necessary for diagnosed excised by VABB.From January 2003 December 2011, total 6,923 were performed 5,434 patients. Out lesions, 53 tumors. Among these, 31 with follow-up...
To evaluate the usefulness and safety of vacuum-assisted breast biopsy (VABB) for lesion diagnosis treatment.Clinical histopathological data 8,748 patients, who underwent 11,221 VABB procedures were analyzed.Most patients (58.2%) <40 years old. Most lesions (39.6%) 0.6-1.0 cm in diameter while 3.2% ≥3.0 cm; fibroadenomas most common (46.6%). Eight (14% 57) cases atypical ductal hyperplasia underestimated. The positive predictive values (PPVs) imaging reporting system (BI-RADS) ultrasound...
Abstract Epidermal inclusion cysts rarely occur in the breast, but when they do, consequences can be severe. Here, we report case of a 23‐year‐old woman who presented with palpable mass right breast. The had persisted for 4 years and been causing pain 1 month at time patient's presentation. We examined by means mammography sonography. Sonographic examination revealed well‐circumscribed solid, avascular suggestive an epidermal cyst. Excision was performed request. Histopathologic after...
trance) of breast and ovarian cancers among female family members with BRCA1 BRCA2 mutation. Methods: Among the 61 mutation carriers in 42 families 47 31 identified at 5 academic clinics, probands were excluded to estimate cumulative risk till each age cancer Korean carriers. Using Kaplan-Meier analyses, estimates determined. Results: By 70, for was 72.1% (95% confidence interval [CI]=59.5% 84.8%) 66.3% CI=41.2% 91.5%), respectively, 24.6% CI=0% 50.3%) 11.1% CI= The Breast Ovarian Cancer...
Mutations in BRCA genes are the main cause of hereditary breast cancer Korea. The aim this study was to investigate characteristics cancers involving BRCA1 (BRCA1 group) and BRCA2 (BRCA2 mutations.We retrospectively reviewed medical records patients with or mutation positive from multiple centers compared data that Korean Breast Cancer Society registry (registry group).The group were diagnosed at a younger age (median age, 37 years) had tumors higher histological (61.3% grade 3) nuclear...
The purpose of our study was to evaluate the utility American College Radiology's Breast Imaging Reporting and Data System (BI-RADS) sonographic final assessment system palpation-guided fine-needle aspiration (FNA) for evaluation palpable breast lesions.Our computerized database identified 160 lesions in which follow-up FNA, targeted sonography, pathologic confirmation were performed. We used BI-RADS data on all lesions. sensitivity, specificity, accuracy, positive predictive value, negative...
Background/Aim: Recently, the development of ultrasonography (US)-guided vacuum-assisted breast biopsy (VABB) has enabled excision benign tumors with normal surrounding tissues; thus, complete is possible without residual tumor tissue. We sought to identify clinicopathological characteristics and recurrence rates phyllodes diagnosed by US-guided VABB. Patients Methods: Data from 11,221 VABBs performed at Gangnam Cha Medical Center over 12 years were analyzed. Eighty-three lesions as tumors;...
Purpose:The objective of this study was to evaluate the change in practice patterns for managing hereditary breast and ovarian cancer (HBOC) among Korean physicians after Hereditary Breast Cancer (KOHBRA) study.Methods: The first survey performed from July August 2007, at initiation KOHBRA study, followup conducted December 2009.Members Society were invited participate by e-mail.The 2009 with a self-administered questionnaire concerning HBOC management identical previous...