A5087413706- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Heavy metals in environment
- Mercury impact and mitigation studies
- Nutritional Studies and Diet
- Carcinogens and Genotoxicity Assessment
- Health, Environment, Cognitive Aging
- Fatty Acid Research and Health
- Environmental Justice and Health Disparities
- Trace Elements in Health
- Per- and polyfluoroalkyl substances research
- Ethics in Clinical Research
- Iron Metabolism and Disorders
- Pesticide Exposure and Toxicity
- Noise Effects and Management
- Child Nutrition and Water Access
- Hemoglobinopathies and Related Disorders
- Vehicle emissions and performance
- Radioactivity and Radon Measurements
- Chemical Safety and Risk Management
- Air Quality Monitoring and Forecasting
- Health and Medical Research Impacts
- Water Treatment and Disinfection
Karolinska Institutet
2014-2024
European Society for Blood and Marrow Transplantation
2020
National Food Administration
2016
National Institute of Public Health
2014
Örebro University
2012
Linköping University
2012
Stockholm Environment Institute
2000
Falun Hospital
1993
This report provides a review of the cadmium exposure situation in Sweden and updates information on health risk assessment according to recent studies effects cadmium. The focuses low doses identification high-risk groups. diet is main source Swedish nonsmoking general population. average daily dietary intake about 15 micrograms/day, but there are great individual variations due differences energy habits. It has been shown that high fiber rich shellfish increase substantially. Cadmium...
Phthalates may pose a risk for perinatal developmental effects. An important question relates to the choice of suitable biological matrices assessing exposure during this period.This study was designed measure concentrations phthalate diesters or their metabolites in breast milk, blood serum, and urine evaluate suitability phthalates.In 2001, 2-3 weeks after delivery, 42 Swedish primipara provided blood, samples at home. Special care taken minimize contamination with phthalates (e.g., use...
Chemicals such as phthalates, parabens, bisphenol A (BPA) and triclosan (TCS), used in a wide variety of consumer products, are suspected endocrine disrupters although their level toxicity is thought to be low. Combined exposure may occur through ingestion, inhalation dermal exposure, toxic well combined effects poorly understood. The objective the study was estimate these chemicals Swedish mothers children (6–11 years old) investigate potential predictors exposure. Urine samples from 98...
Children are exposed to a wide range of chemicals in their everyday environments, including the preschool. In this study, we evaluated levels phthalates, non-phthalate plasticizers and bisphenols dust from 100 Swedish preschools identified important exposure factors indoor environment. addition, children's total these was determined by urine analysis investigate relation with exposure, explore time trends comparing children who provided fifteen years earlier. The most abundant preschool were...
Measurements of intake and uptake cadmium in relation to diet composition were carried out 57 nonsmoking women, 20-50 years age. A vegetarian/high-fiber a mixed-diet group constructed based on results from food frequency questionnaire. Duplicate diets the corresponding feces collected during 4 consecutive days parallel with dietary recording type amount ingested for determination various nutrients. Blood 24-hr urine samples cadmium, hemoglobin, ferritin, zinc. There no differences nutrients...
Biomarkers for mercury (Hg) exposure have frequently been used to assess and risk in various groups of the general population. We evaluated most biomarkers physiology on which they are based, explore inter-individual variations their suitability assessment.Concentrations total Hg (THg), inorganic (IHg) organic (OHg, assumed be methylmercury; MeHg) were determined whole blood, red blood cells, plasma, hair urine from Swedish men women. An automated multiple injection cold vapour atomic...
Objectives. The purpose of this study was to determine the impact iron status on cadmium dose among pregnant women. Methods. Iron and concentration in blood, urine, placenta were determined women followed for 2 years from early pregnancy. Results. Blood urinary correlated with throughout period. Urinary increased longitudinally exhausted stores during their increase age more pronounced multiparous than nulliparous Conclusions. deficiency pregnancy leads absorption body burden. Multiparous...
We studied exposure to methyl mercury (MeHg) in Swedish pregnant women (total [T-Hg] hair) and their fetuses (MeHg cord blood) relation fish intake. The were recruited at antenatal care clinics late pregnancy participate an study of environmental pollutants. Fish consumption was evaluated using food frequency questionnaires including detailed questions on consumption. In addition, we determined inorganic (I-Hg) selenium (Se) blood. On average, the consumed (all types) 6.7 times/month (range...
For Europe as a whole, data on internal exposure to environmental chemicals do not yet exist. Characterization of the individual chemical environment is expected enhance understanding threats health.We developed and applied harmonized protocol collect comparable human biomonitoring all over Europe.In 17 European countries, we measured mercury in hair cotinine, phthalate metabolites, cadmium urine 1,844 children (5-11 years age) their mothers. Specimens were collected 5-month period...
Due to global mercury pollution and the adverse health effects of prenatal exposure methylmercury (MeHg), an assessment economic benefits prevented developmental neurotoxicity is necessary for any cost-benefit analysis.Distributions hair-Hg concentrations among women reproductive age were obtained from DEMOCOPHES project (1,875 subjects in 17 countries) literature data (6,820 8 countries). The exposures assumed comply with log-normal distributions. Neurotoxicity estimated a linear...
Children ingest soil. The amount ingested varies with the child's behaviour, and daily ingestion rates have been calculated to be between 39 270 mg day− 1. During play, children soil both involuntarily deliberately, it can assumed that latter may result in of a larger particle size fraction mass than former. Measurements metal contents commonly display total content, where sieved < 2 mm has digested strong acids. This procedure does not consider differences fractions or masses. Moreover,...
Abstract Background Breast milk is the best source of nutrition for newborn infant. However, since all infants cannot be breast-fed, there a need background data setting adequate daily intakes. Previously, concentration on major essential elements and some toxic in breast milk, based different analytical techniques, have been published. There no recent study large number metals trace using sensitive method determination low element concentrations. Methods concentrations 32 early lactation...
The toxicity of methylmercury (MeHg) in humans is well established and the main source exposure via consumption large marine fish mammals. Of particular concern are potential neurodevelopmental effects early life to low-levels MeHg. Therefore, it important that pregnant women, children women childbearing age are, as far possible, protected from MeHg exposure. Within European project DEMOCOPHES, we have analyzed mercury (Hg) hair 1799 mother-child pairs 17 countries using a strictly...
Children spend a considerable part of their day in preschool, where they may be exposed to hazardous chemicals indoor dust. In this study, brominated flame retardants (BFRs) and organophosphate esters (OPEs) were analyzed preschool dust (n = 100) children's hand wipe samples 100), diphenyl phosphate (DPHP) was urine 113). Here we assessed exposure via dust, identified predictors for studied correlations between different measures. The most abundant BFRs decabromodiphenyl ether (BDE-209)...
We determined levels of inorganic mercury (I-Hg) and methylmercury in placentas from 119 Swedish women, not selected with respect to high exposure mercury. Our objective was relate placental Hg species maternal fetal blood concentrations evaluate possible associations selenium. performed the analyses using automated alkaline solubilization/reduction cold-vapor atomic fluorescence spectrophotometry. I-Hg placenta increased an increasing number dental amalgam fillings (p < 0.001). Despite...