A5102027542- Nanoplatforms for cancer theranostics
- Polymer Surface Interaction Studies
- Nanoparticle-Based Drug Delivery
- Advanced Polymer Synthesis and Characterization
- Metal-Organic Frameworks: Synthesis and Applications
- Lanthanide and Transition Metal Complexes
- Marine Biology and Environmental Chemistry
- Luminescence and Fluorescent Materials
- Covalent Organic Framework Applications
- MXene and MAX Phase Materials
- Supramolecular Chemistry and Complexes
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
- Antimicrobial agents and applications
- Supramolecular Self-Assembly in Materials
- Identification and Quantification in Food
- Membrane Separation Technologies
- Hydrogen embrittlement and corrosion behaviors in metals
- Advanced Photocatalysis Techniques
- Dendrimers and Hyperbranched Polymers
- Advanced NMR Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Boron and Carbon Nanomaterials Research
- Enzyme-mediated dye degradation
- Chromium effects and bioremediation
The University of Queensland
2020-2025
Institute of Bioengineering and Nanotechnology
2025
Shaoxing University
2016-2023
Sun Yat-sen University
2019-2023
University of Science and Technology of China
2022
Ningbo Science and Technology Bureau
2022
Weifang Medical University
2022
China-Japan Friendship Hospital
2016
Fuzhou University
2012
Cancer theranostics that combines cancer diagnosis and therapy is a promising approach for personalized treatment. However, current theranostic strategies suffer from low imaging sensitivity visualization an inability to target the diseased tissue site with high specificity, thus hindering their translation clinic. In this study, we have developed tumor microenvironment-responsive hybrid agent by grafting water-soluble, low-fouling fluoropolymers pH-responsive zeolitic imidazolate...
Biofouling caused by nonspecific adsorption of biomolecules and organisms such as proteins, cells, bacteria to material surfaces is a significant challenge for numerous important applications. An effective approach addressing this problem coat antifouling polymers on the impart demanded properties repel biological adhesion. In review, we summarized recent advances in surface polymer brushes which have emerged past decade, with focus origin brushes, approaches key factors that impact...
Antifouling surfaces are important in a broad range of applications. An effective approach to antifouling is covalently attach polymer brushes. This work reports the synthesis new class brushes based on highly hydrophilic sulfoxide polymers by surface-initiated photoinduced electron/energy transfer-reversible addition-fragmentation chain transfer (PET-RAFT) polymerization. The able effectively reduce nonspecific adsorption proteins and cells, demonstrating remarkable properties. Given...
Antifouling and antibacterial surfaces that can prevent nonspecific biological adhesion are important to support a myriad of biomedical applications. In this study, we have used an innovative photopolymerization technology develop sulfur-containing polymer-grafted antifouling surfaces. The relationship between the hydrophilic property capability resist protein macrophage adsorption surface copolymer brushes was investigated. sulfide monomer incorporated into be further ionized carry positive...
The conjugation of hydrophilic polymers to proteins is an effective approach prolonging their circulation time in the bloodstream and, hence, improving delivery target region interest. In this work, we report synthesis protein-polymer conjugates using a highly water-soluble sulfoxide-containing polymer, poly(2-(methylsulfinyl)ethyl acrylate) (PMSEA), through combination "grafting-to" and "grafting-from" methods. Oligomeric MSEA was synthesized by conventional reversible...
Non-thrombogenic surfaces for extracorporeal membrane oxygenation (ECMO) devices are important to increase their duration of usage and enable long-term life support. However, the contact blood with hydrophobic synthetic ECMO materials such as poly(4-methyl-1-pentene) (PMP) can activate coagulation cascade, causing thrombosis a series consequent complications during operation. Targeting this problem, we proposed graft highly hydrophilic sulfoxide polymer brushes onto PMP via gamma ray...
Responsive polymeric nanoparticles have been extensively studied for various biological applications to provide enhanced function accuracy. Here, we report the synthesis of oxidation-responsive fluorinated (FNPs) via a photopolymerization-induced self-assembly (photo-PISA) method using thioether- and fluorine-containing monomer N-(2-((2,2,2-trifluoroethyl)thio)ethyl)acrylamide (FTAM) methoxy polyethylene glycol (mPEG)-based macro chain transfer agent. With polymerization FTAM, resultant...
Polymeric fluorinated nanoparticles (PFNPs) are useful materials in many applications, especially the field of 19F magnetic resonance imaging (MRI). Despite development numerous PFNPs with diverse chemical compositions and structures, those high fluorine content capable highly sensitive MRI remain scarce. Here we report an elegantly designed aqueous photo-polymerization-induced self-assembly (photo-PISA) system for synthesis effective applications. This innovative photo-PISA is enabled by...
Since organic pollutants in water resources have raised concerns on aquatic ecosystems and human health, mechanical machines such as a nanopump for rapid efficient removal of from with regeneration properties remains challenge. Here, pH-responsive artificial pump left-handed porous tubules into right-handed solid fibers was presented by the self-assembly bent-shaped aromatic amphiphiles. The amphiphile pH-sensitive segment demonstrated hexameric macrocycles, which could contract dimeric...
To obtain high tumor-specific accumulation, strong tumor penetration and low off-target uptake, we developed a series of polymer therapeutics with different architectures, including random, block, brush-like structure, based on the classic N-(2-hydroxypropyl) methacrylamide polymers. The influence architecture biological properties such as cellular blood clearance, biodistribution have been investigated. Besides small micelles whose sizes were determined by large aggregates formed micelle...
ABSTRACT The relationships between the chemical structures and hydration environment of polymers can provide significant insight into water‐amphiphilic polymer interactions. Here, hydrophobicity amphiphilic block copolymers poly(ethylene tartaramide‐ b ‐alkyl isocyanate) is gradually tuned by using a series pendant alkyl (isopropyl, n ‐butyl, cyclopentyl, cyclohexyl) groups. Dynamics probed low‐field NMR relaxometry exhibits heterogeneous water molecules, corresponding to tightly bound with...
Rapid and selective removal of micropollutants from water is important for the reuse resources. Despite hollow frameworks with specific functionalized porous walls adsorption based on a series interactions, tailoring stable shape nanometer- micrometer-sized architectures pollutants remains challenge. Here, exactly controlled sheets, tubes, spherical were presented crosslinking supramolecular colloids in polar solvents. The strongly depended architecture original colloids. As entropy...
Despite the success for targeted delivery in body, efficient release without side effects caused by residual drug remains a challenge. For reducing drug, pH-responsive carriers were prepared self-assembly from aromatic macrocycles, which non-toxic and biocompatible. The inner surroundings of macrocycles could be protonated positively acid inducing separation neighboring macrocycles. Thus, Dox-loaded successfully inhibited proliferation carcinoma cells (HepG2 4T1) rather than normal (HL7702)....
In this work, the adsorption of SF 6 decomposition products (SO 2 , SOF and SO F ) on Ru–MoTe monolayer is investigated based density‐functional theory (DFT) calculations. The doping structure, band energy, charge transfer, density states (DOS), molecular orbital are analyzed to better analyze interaction mechanism between gas molecules system. results, it shown that conductivity MoTe can be greatly increased by Ru atom. Pristine shows a weak capacity for gases, which belongs physical...
Despite many cationic nanomaterials that have been developed for efficient adsorption of anionic pollutants, tailoring a stable shape with denser cations on the surface advanced removal capability remains challenging. Here, new strategy is presented fabricating two-dimensional (2D) laminas and their curvature based cross-linking 2D supramolecular networks from hydrogen-bonded trimesic amide derivatives. Owing to distribution most surface, two nanostructures show fast sorption kinetics...
Gold nanorods (GNRs) are widely used in various biomedical applications such as disease imaging and therapy due to their unique plasmonic properties. To improve bioavailability, GNRs often need be coated with hydrophilic polymers so impart stealth Poly(ethylene glycol) (PEG) has been long a coating material for GNRs. However, there is increasing acknowledgement that the amphiphilic nature of PEG facilitates its interaction protein molecules, leading immune recognition consequent side...
A tubular catalyst showed fast catalytic kinetics for CO 2 conversion with a TON of 2300 and TOF up to 173 h −1 .
Abstract Rapid and selective removal of micropollutants from water is important for the reuse resources. Despite hollow frameworks with specific functionalized porous walls adsorption based on a series interactions, tailoring stable shape nanometer‐ micrometer‐sized architectures pollutants remains challenge. Here, exactly controlled sheets, tubes, spherical were presented crosslinking supramolecular colloids in polar solvents. The strongly depended architecture original colloids. As entropy...