A5042930699- Spectroscopy Techniques in Biomedical and Chemical Research
- Spectroscopy and Chemometric Analyses
- Photodynamic Therapy Research Studies
- Advanced Radiotherapy Techniques
- Optical Imaging and Spectroscopy Techniques
- Protein Interaction Studies and Fluorescence Analysis
- Metabolomics and Mass Spectrometry Studies
- Lanthanide and Transition Metal Complexes
- Oral Health Pathology and Treatment
- Nanoplatforms for cancer theranostics
- Radiation Therapy and Dosimetry
- Gold and Silver Nanoparticles Synthesis and Applications
- Medical Imaging Techniques and Applications
- Nanoparticles: synthesis and applications
- Porphyrin and Phthalocyanine Chemistry
- Metal complexes synthesis and properties
- Laser Applications in Dentistry and Medicine
- Radiation Dose and Imaging
- Nonlinear Optical Materials Studies
- Quantum Dots Synthesis And Properties
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- bioluminescence and chemiluminescence research
- Semiconductor materials and devices
- Laser-Ablation Synthesis of Nanoparticles
Anna University, Chennai
2016-2025
Avinashilingam University
2021-2025
Creative Commons
2023
Lakeshore Hospital
2023
University of Madras
2012
All India Institute of Medical Sciences
2011
Lund University
2002
Abstract A series of Au-doped TiO 2 nanoparticles with different Au concentrations were prepared by the sol–gel method using titanium (IV) isopropoxide and tetrachloroaurate (III) trihydrate as precursors. The framework substitution in was established x-ray diffraction (XRD) Fourier transform infrared (FT-IR) techniques. X-ray transmission electron microscopy (TEM) image results confirmed anatase phase nanocrystalline nature –Au. optical properties revealed an extended tailing absorption...
Urine is considered as one of the diagnostically important bio fluids, it has many metabolites. The distribution and physiochemical properties metabolites may vary during any altered metabolic pathological conditions. Raman spectroscopy was employed in characterization human urine normal subjects oral cancer patients finger print region (500–1800 cm −1 ). Principal component analysis‐based linear discriminant analysis performed to discriminate from subjects. classifies with a sensitivity...
4-[(1Z)-1-(2-carbamothioylhydrazinylidene)ethyl]phenyl acetate [Ace semi],4-[(1Z)-1-(2-carbamothioylhydrazinylidene)ethyl]phenyl propanoate [Pro semi] from the family of thiosemicarbazones derivative has been newly synthesized. It good anticancer activity as well antibacterial and it is also less toxic in nature, its binding characteristics are therefore huge interest for understanding pharmacokinetic mechanism drug. The thiosemicarbazone to human serum albumin (HSA) investigated by studying...
Native fluorescence characteristics of blood plasma were studied in the visible spectral region, at two different excitation wavelengths, 405 and 420 nm, to discriminate patients with stages oral malignancy from healthy subjects. The spectra malignant subjects exhibit characteristic differences respect normal Different ratios calculated using intensity values those emission wavelengths that give features each group experimental studied. These used as input variables for a multiple linear...
In this present study on understanding the taxol (PTX) binding interaction mechanism in both β-tubulin and bovine serum albumin (BSA) molecule, various optical spectroscopy computational techniques were used. The fluorescence steady-state emission result suggests that there is a static quenching of PTX drug BSA, further time-resolved studies confirm exists. excitation–emission matrix (EEM), Fourier transform infrared, resonance light scattering spectra (FT-IR) are structural changes BSA...
The objective of this study was to assess the diagnostic potential synchronous fluorescence (SF) spectroscopy (SFS) technique for detection and characterization normal different malignancy stages moderately differentiated squamous cell carcinoma (MDSCC), poorly (PDSCC) cervical tissues. SF spectra were measured from 45 biopsies 30 patients in vitro. Characteristic, highly resolved peaks significant spectral differences between MDSCC, PDSCC tissues obtained. Nine ratios calculated used as...
In the present study, Raman spectroscopy has been employed in discrimination of saliva normal subjects from patients with oral submucous fibrosis and squamous cell carcinomaat 785‐nm excitation. From spectral signatures, prominent difference between abnormal group because variations metabolic pathological conditions was observed. Principal component analysis coupled linear discriminant yielded a diagnostic sensitivity 96.4 93.8% specificity 70.2 95.7% classification premalignant malignant,...
Viral infections cause significant health problems all over the world, and it is critical to develop treatments for these problems. Antivirals that target viral genome-encoded proteins frequently virus become more resistant treatment. Because viruses rely on several cellular phosphorylation processes are essential their life cycle, drugs targeting host-based targets could be a viable treatment option. To reduce costs improve efficiency, existing kinase inhibitors repurposed as antiviral...
In today’s world, every product has become artificial and instantaneous due to rapid technological development. Consumers are shifting healthier diets, packaged food companies introducing more functional items with immunity claims incorporating nutritious ingredients into their products. Due the increased production, products that ordinary people receive have many flaws defects. Spectroscopic approaches unique probing techniques characterize various compounds in a find rectify...
<title>Abstract</title> Oral potentially malignant disorders (PMD) are heterogenous group of oral conditions characterized by increased risk transformation that commonly diagnosed clinically and treated. Tissue biopsy is an invasive tool for diagnosis PMDs. Native fluorescence spectroscopy biofluids currently the area interest, as a non-invasive method to differentiate between normal cancer patients. This study, primarily aimed characterize three common intrinsic fluorophores present in...
4-[3-acetyl-5-(acetylamino)-2,3-dihydro-1,3,4-thiadiazole-2-yl]phenyl benzoate from the family of thiadiazole derivative has been newly synthesized. It good anticancer activity as well antibacterial and less toxic in nature, its binding characteristics are therefore huge interest for understanding pharmacokinetic mechanism drug. The to human serum albumin (HSA) investigated by studying quenching mechanism, kinetics molecular distance, r between donor acceptor (thiadiazole derivative) was...
The present study focuses on the determination of biologically significant N-acetylneuraminic acid (NANA) drug binding interaction mechanism between bovine serum albumin (BSA) and human α-1 glycoprotein (HAG) using various optical spectroscopy computational methods. steady state fluorescence result suggests that intensity BSA HAG was quenched by NANA in a static mode quenching. Further time-resolved emission measurements confirm quenching system. FT-IR, excitation–emission matrix circular...