A5000336600- Shoulder Injury and Treatment
- Spine and Intervertebral Disc Pathology
- Knee injuries and reconstruction techniques
- Tendon Structure and Treatment
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Musculoskeletal pain and rehabilitation
- Sports injuries and prevention
- Hip and Femur Fractures
- Bone fractures and treatments
- Neuroscience of respiration and sleep
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Venous Thromboembolism Diagnosis and Management
- Tryptophan and brain disorders
- Elbow and Forearm Trauma Treatment
- Nerve Injury and Rehabilitation
- Cardiac Arrest and Resuscitation
- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- Metastasis and carcinoma case studies
- Frailty in Older Adults
- Pelvic and Acetabular Injuries
VA Pittsburgh Healthcare System
2024-2025
University of Pittsburgh
2023-2025
Dalian Medical University
2021-2024
Second Affiliated Hospital of Dalian Medical University
2022-2024
University of Pittsburgh Medical Center
2023-2024
Cornell University
2014-2024
Temple University
2024
Hospital for Special Surgery
2015-2024
University of Nebraska Medical Center
2024
Mount Sinai Medical Center
2024
Object Extreme lateral interbody fusion (ELIF) is a popular technique for anterior fixation of the thoracolumbar spine. Clinical and radiological outcome studies are required to assess safety efficacy. The aim this study was describe functional impact ELIF in degenerative disc disease population with longer follow-up durability procedure. Methods Demographic perioperative data all patients who had undergone lumbar disorders between 2007 2011 were collected. Trauma tumor cases excluded. For...
Background: There is no consensus among sports medicine surgeons in North America on postoperative rehabilitation strategy after meniscus repair. Various meniscal tear types may necessitate a unique range of motion (ROM) and weightbearing protocol. Purpose: To assess the current landscape how practitioners American Orthopedic Society for Sports Medicine (AOSSM) rehabilitate patients repair varying tears. Study Design: Cross-sectional study. Methods: A survey was distributed to 2973 AOSSM...
Background: The glenoid track concept for shoulder instability primarily describes the medial-lateral relationship between a Hill-Sachs lesion and glenoid. However, position in craniocaudal dimension has not been thoroughly studied. Hypothesis: lesions with greater inferior extension are associated increased risk of recurrent after primary arthroscopic Bankart repair. Study Design: Case-control study; Level evidence, 3. Methods: authors performed retrospective analysis patients on-track who...
Radiculopathy caused by foraminal nerve root compression is a common pathology in the lumbar spine. Surgical decompression via conventional open foraminotomy treatment of choice when surgery indicated. Minimally invasive tubular through contralateral approach potentially effective surgical alternative.The aim this retrospective cohort study was to evaluate efficacy and benefits for radiculopathy.Patients with unilaterally dominant lower extremity radiculopathy, who underwent minimally...
Following anterior cruciate ligament (ACL) reconstruction, the mechanical loading of tissues has a significant impact on tendon-to-bone healing. The purpose this study was to determine effect timing initiation healing tendon graft in bone tunnel.ACL reconstruction using flexor autograft performed 56 mice randomized 4 groups with differing times postoperative loading: (1) immediate, (2) 5 days, (3) 10 or (4) 21 days following surgery. An external fixator placed across knee at time surgery and...
Abstract Major depressive disorder (MDD) refers to a widespread psychiatric disorder. Astrocytes play pivotal role in regulating inflammation which is well-acknowledged key component depression pathogenesis. However, the effects of neuroinflammation-inducing A1-like astrocytes on MDD are still unknown. TWIK-related K + channel 1 (TREK-1) has been demonstrated regulate action antidepressants. Nevertheless, its mechanisms and astrocyte stimulation not clear. Therefore, we conducted vivo vitro...
Polysaccharides from Dendrobium officinale possess unparalleled medicinal value. In order to produce the active polysaccharides D. through tissue culture, effects of salicylic acid on accumulation were investigated. Salicylic (SA) was beneficial increasing contents polysaccharides. The highest polysaccharide production occurred medium supplied with 100 μmol·L− 1 acid. After 30 days culture reached 10.09% and 15.81% by phenol-sulfuric method 3, 5-dinitrosalicylic (DNS) colorimetric...
ABSTRACT Subacromial impingement of the rotator cuff is understood as a contributing factor in development tendinopathy. However, changes that occur impinged tendon are poorly and warrant further study. To enable study tendinopathy, we performed controlled laboratory to determine feasibility baseline characteristics new murine model for subacromial impingement. This involves surgically inserting microvascular clip into space adult C57Bl/6 mice. Along with sham surgery arm, 90 animals were...
Mechanical stress has an important effect on tendon-to-bone healing. The purpose of the present study was to compare healing in animals exposed either tendon unloading (botulinum toxin injection) or excessive loading (treadmill running) a murine rotator cuff repair model. Forty-eight C57BL/6 mice underwent unilateral supraspinatus detachment and repair. Mice unloaded group were injected with botulinum muscle. contralateral shoulder used as control. euthanized at 1, 2, 4 weeks after surgery...
Tendon-to-bone repair remains a surgical challenge. Although bone tunnel fixation is common technique whereby soft tissue expected to heal against interface, contemporary methods have yet recapitulate biomechanical similarity the native enthesis. In this study, we aimed understand how inside-out longitudinal tendon inversion affects healing with hypothesis that removes gliding epitenon surface facilitate interface healing. Forty male Sprague-Dawley rats underwent either tenodesis (control...
Abstract Background: Open reduction and internal fixation for fractures of the subchondral bone (including articular impaction fractures, insufficiency early-collapse in avascular necrosis) is difficult or impossible difficult-to-reach anatomic regions. Indirect methods utilizing calcium phosphate cementation has been tried with a near 50% failure rate 22% conversion to arthroplasty. On other hand, open grafting employed success. Here we present first cadaveric series demonstrating fracture...
Background: Recent literature has shown that inferior Hill-Sachs extension for on-track shoulders is predictive of recurrent instability after arthroscopic Bankart repair alone. Specifically, there a high risk when the lesion extends below humeral equator on sagittal magnetic resonance imaging. This worrisome been termed “critical bone loss (CHBL).” Remplissage yet to be explored as potential useful augmentation in patients with CHBL. Hypothesis: The addition remplissage would decrease...