A5041529144- Tracheal and airway disorders
- Airway Management and Intubation Techniques
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Dysphagia Assessment and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Trauma Management and Diagnosis
- Respiratory Support and Mechanisms
- Pneumothorax, Barotrauma, Emphysema
- Medical Imaging and Pathology Studies
- Esophageal and GI Pathology
- Ultrasound in Clinical Applications
- Epilepsy research and treatment
- Voice and Speech Disorders
- Lung Cancer Treatments and Mutations
- Cardiac Arrest and Resuscitation
- Vascular Anomalies and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- COVID-19 Clinical Research Studies
- Central Venous Catheters and Hemodialysis
- Congenital Diaphragmatic Hernia Studies
- COVID-19 and healthcare impacts
- Family and Patient Care in Intensive Care Units
- Respiratory and Cough-Related Research
- Advanced Radiotherapy Techniques
Hadassah Medical Center
2019-2025
Harvard University
2012-2025
Beth Israel Deaconess Medical Center
2017-2025
Parul University
2025
The University of Texas Southwestern Medical Center
2019-2024
NVision Eye Centers (United States)
2023
Icahn School of Medicine at Mount Sinai
2008-2022
Children's Hospital of Philadelphia
2020
Pulmonary and Critical Care Associates
2020
SleepMed
2020
Rationale: This is the first multicenter randomized controlled trial to evaluate effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little no collateral ventilation out 12 months.Objectives: To EBV heterogeneous emphysema treated lobe.Methods: Subjects were enrolled a 2:1 randomization (EBV/standard care [SoC]) at 24 sites. Primary outcome months was ΔEBV–SoC subjects post-bronchodilator FEV1 improvement from baseline greater than or equal 15%. Secondary endpoints...
PurposeTo compare the ocular hypotensive efficacy and safety of a fixed-dose combination (FDC) Rho kinase inhibitor netarsudil latanoprost vs monotherapy with or latanoprost.DesignThree-month primary endpoint analysis randomized, double-masked, phase 3 clinical trial.MethodsAdults open-angle glaucoma hypertension (unmedicated intraocular pressure [IOP] >20 <36 mm Hg at 8:00 AM) were randomized to receive once-daily netarsudil/latanoprost FDC, 0.02%, 0.005% for up 12 months. The was mean IOP...
Traditional bronchoscopy provides limited approach to peripheral nodules. Shape-sensing robotic-assisted (SSRAB, Ion™ Endoluminal System) is a new tool for minimally invasive nodule biopsy. We sought answer the research question: Does SSRAB facilitate sampling of pulmonary nodules during bronchoscopists' initial experience?The lead-in stage multicenter, single-arm, prospective evaluation Ion System (PRECIsE) described. Enrolled subjects ≥ 18 years old had recent computed tomography evidence...
Rationale: Pleural infection is frequently encountered in clinical practice and associated with high morbidity mortality. Limited evidence exists regarding the optimal treatment. Although both early medical thoracoscopy (MT) tube thoracostomy intrapleural instillation of tissue plasminogen activator human recombinant deoxyribonuclease are acceptable treatments for patients complicated pleural infection, there a lack comparative data these modes management.Objectives: The aim this study was...
Effective communication between intensive care unit (ICU) providers and families is crucial given the complexity of decisions made regarding goals therapy. Using video images to supplement medical discussions an innovative process standardize improve communication. In this six-month, quasi-experimental, pre-post intervention study we investigated impact a cardiopulmonary resuscitation (CPR) decision support tool upon knowledge about CPR among surrogate makers for critically ill adults.We...
We used a living bilayered cultured skin replacement to close full-thickness wound defects on the dorsum of athymic mice. The is composed human fibroblasts that condense bovine collagen lattice; lattice then seeded with keratinocytes. serves as dermal template, and overlying keratinocytes form epidermal component this composite replacement. Twenty-four animals were grafted, groups six killed biopsied at 6, 15, 30, 60 days after graft mice in control group receiving grafts fresh,...
Treatment of pleural infection with instillation sequential intrapleural tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase) twice daily for a total 6 doses has been shown to decrease surgical referral improve radiographic imaging. This labor-intensive regimen was empirically chosen. Thus, it remains unclear whether the 2 drugs can be administered immediately one after other (concurrent administration) instead instilling them separately 1-hour 2-hour interval...
Aims Fam-trastuzumab deruxtecan-nxki (T-DXd) was recently approved for advanced stage or metastatic solid tumours with human epidermal growth factor receptor 2 (HER2) immunohistochemical (IHC) 3+ staining. Data on HER2 IHC testing and knowledge of genomic correlates in lung cancer are scarce. This study analyses characteristics HER2-expressing addresses issues preanalytical variables specimens. Methods staining performed selected archival cytology surgical pathology specimens patients...