Nicholas J. Pastis

ORCID: 0009-0005-0261-5986
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Tracheal and airway disorders
  • Pleural and Pulmonary Diseases
  • Lung Cancer Treatments and Mutations
  • Ultrasound in Clinical Applications
  • Airway Management and Intubation Techniques
  • Medical Imaging and Pathology Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Atomic and Subatomic Physics Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Anesthesia and Sedative Agents
  • Respiratory Support and Mechanisms
  • Esophageal Cancer Research and Treatment
  • Vascular Anomalies and Treatments
  • Surgical Simulation and Training
  • Simulation-Based Education in Healthcare
  • Intensive Care Unit Cognitive Disorders
  • Cardiac Arrhythmias and Treatments
  • Trauma Management and Diagnosis
  • Lung Cancer Research Studies
  • Cardiac Arrest and Resuscitation
  • Occupational and environmental lung diseases
  • Respiratory and Cough-Related Research
  • Advanced Radiotherapy Techniques

The Ohio State University Wexner Medical Center
2023-2025

Lung Institute
2025

The Ohio State University
2022-2025

Ohio State University Hospital
2022-2025

Medical University of South Carolina
2012-2021

SleepMed
2017-2021

Johns Hopkins Hospital
2020

Southwest Washington Medical Center
2020

The University of Texas MD Anderson Cancer Center
2020

Ralph H. Johnson VA Medical Center
2020

Gerard J. Criner Richard Sue Shawn E. Wright Mark T. Dransfield Hiram Rivas-Perez and 95 more Tanya Wiese Frank C. Sciurba Pallav L. Shah Momen M. Wahidi Hugo Goulart de Oliveira Brian Morrissey Paulo Francisco Guerreiro Cardoso Steven R. Hays Adnan Majid Nicholas J. Pastis Lisa Kopas Mark Vollenweider P. Michael McFadden Michael Machuzak David W. Hsia Arthur Sung Nabil Jarad Malgorzata Kornaszewska Stephen R. Hazelrigg Ganesh Krishna Brian Armstrong Narinder S. Shargill Dirk‐Jan Slebos Gerard J. Criner Francis Cordova Parag Desai Nathaniel Marchetti Victor Kim Kartik Shenoy John M. Travaline Jiji Thomas Lii-Yoong H. Criner Richard Sue Shawn E. Wright Aaron Thornburg Terry Thomas Mark T. Dransfield Surya P. Bhatt J. Michael Wells Necole Seabron-Harris Hiram Rivas-Perez Umair Gauhar Tanya Wiese Crissie Despirito Frank C. Sciurba Jessica Bon Field Divay Chandra Joseph K. Leader Roy Semaan Christina M. Ledezma Pallav L. Shah Samuel V. Kemp Justin Garner Arafa Aboelhassan Karthi Srikanthan Eric Daniel Tenda A.M López Abraham Cai Sim Momen M. Wahidi Kamran Mahmood Scott Shofer Kathleen Coles Hugo Goulart de Oliveira Guilherme A. P. de Oliveira Betina Machado Igor Gorski Benedetto Fábio Munhoz Svartman Amarilio de Macedo Neto Leonardo Schreiner Taiane Alves Vieira Brian Morrissey Ken Y. Yoneda Tristan Tham Daniel Tompkins Paulo Francisco Guerreiro Cardoso Rodrigo Abensur Athanazio Felipe Nominando Samia Zahi Rached Luciana Cassimiro Steven R. Hays Eric J. Seeley Pavan Shrestha Gabriela R. Dincheva Adnan Majid Daniel Alape Mihir Parikh Alichia Paton A. Agnew Nicholas J. Pastis Charlie Strange Tatsiana Beiko Danielle Woodford Mary Blanton Lisa Kopas Timothy M. Connolly

Rationale: This is the first multicenter randomized controlled trial to evaluate effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little no collateral ventilation out 12 months.Objectives: To EBV heterogeneous emphysema treated lobe.Methods: Subjects were enrolled a 2:1 randomization (EBV/standard care [SoC]) at 24 sites. Primary outcome months was ΔEBV–SoC subjects post-bronchodilator FEV1 improvement from baseline greater than or equal 15%. Secondary endpoints...

10.1164/rccm.201803-0590oc article EN American Journal of Respiratory and Critical Care Medicine 2018-05-22

The diagnosis of peripheral pulmonary lesions (PPL) continues to present clinical challenges. Despite extensive experience with guided bronchoscopy, the diagnostic yield has not improved significantly. Robotic-assisted bronchoscopic platforms have been developed potentially improve for PPL. Presently, limited data exist that evaluate performance robotic systems in live human subjects.What is safety and feasibility robotic-assisted bronchoscopy patients PPLs?This was a prospective,...

10.1016/j.chest.2020.08.2047 article EN cc-by-nc-nd CHEST Journal 2020-08-19

Advanced diagnostic bronchoscopy targeting the lung periphery has developed at an accelerated pace over last two decades, whereas evidence to support introduction of innovative technologies been variable and deficient. A major gap relates reporting yield, in addition limited comparative studies.

10.1164/rccm.202401-0192st article EN American Journal of Respiratory and Critical Care Medicine 2024-02-23

Context.— The need for appropriate specimen use ancillary testing has become more commonplace in the practice of pathology. This, coupled with improvements technology, often provides less invasive methods testing, but presents new challenges to collection and handling these small specimens, including thoracic biopsy cytology samples. Objective.— To develop a clinical guideline recommendations on how obtain, handle, process tissue specimens diagnostic studies. Methods.— College American...

10.5858/arpa.2020-0119-cp article EN Archives of Pathology & Laboratory Medicine 2020-05-13

<b><i>Background:</i></b> Bronchoscopy for the diagnosis of peripheral pulmonary lesions continues to present clinical challenges, despite increasing experience using newer guided techniques. Robotic bronchoscopic platforms have been developed potentially improve diagnostic yields. Previous studies in cadaver models demonstrated increased reach into lung periphery robotic systems compared similarly sized conventional bronchoscopes, although impact additional is...

10.1159/000504181 article EN cc-by-nc-nd Respiration 2019-12-05

With complex, lengthy bronchoscopies, there is a need for safe, effective sedation. Most bronchoscopists strive moderate sedation, though often difficult without compromising vital signs. The Modified Observer's Assessment of Alertness and Sedation (MOAA/S) scale validated 6-point assessing responsiveness patients coinciding with the American Society Anesthesiologists (ASA) continuum It commonly used in studying bronchoscopic but depth sedation by MOAA/S correlation signs adverse events has...

10.1097/lbr.0000000000000784 article EN Journal of Bronchology & Interventional Pulmonology 2021-07-08

Introduction The presence of intrathoracic lymphadenopathy and mediastinal masses in the pediatric population often presents a diagnostic challenge. With limited minimally invasive methodologies to obtain diagnosis, sampling via mediastinoscopy or thoracotomy is pursued. Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) invasive, outpatient procedure that has demonstrated significant success adult evaluation such abnormalities. Within literature there data regarding use...

10.1002/ppul.22887 article EN Pediatric Pulmonology 2013-09-13

Rationale: Strict adherence to procedural protocols and diagnostic definitions is critical understand the efficacy of new technologies. Electromagnetic navigational bronchoscopy (ENB) for lung nodule biopsy has been used decades without a solid understanding its efficacy, but offers opportunity simultaneous tissue acquisition via electromagnetic transthoracic (EMN-TTNA) staging endobronchial ultrasound (EBUS). Objective: To evaluate yield EBUS, ENB, EMN-TTNA during single procedure using...

10.1164/rccm.202301-0099oc article EN American Journal of Respiratory and Critical Care Medicine 2023-08-15
Dirk‐Jan Slebos Joseph Cicenia Frank C. Sciurba Gerard J. Criner Jorine E. Hartman and 95 more Justin Garner Gaëtan Deslée Antoine Delage Michael A. Jantz Charles‐Hugo Marquette Charlie Strange Umur Hatipoğlu Atul C. Mehta Adam S. LaPrad Gerald Schmid‐Bindert Felix J.F. Herth Pallav L. Shah Felix J.F. Herth Daniela Gompelmann Maren Schuhmann Robert T. Eberhardt Dominik Harzheim B. Rump Dirk‐Jan Slebos Nick ten Hacken Karin Klooster Jorine E. Hartman Sonja W.S. Augustijn Pallav L. Shah Cielito Caneja William McNulty Justin Garner Gaëtan Deslée H. Vallerand Sandra Dury Delphine Gras M. Verdier Charles‐Hugo Marquette C. Sanfiorenzo Cathryn M. Clary C. Leheron J. Pradelli Steven J. Korzeniewski P. Wolter T. S. Arfi F. Macone M. Poudenx Sylvie Leroy A. Guillemart J. Griffonet Charlie Strange Rahul Argula G. Silvestri John T. Huggins Nicholas J. Pastis Donald W. Woodford Lope Estévez Schwarz David Walker Gerard J. Criner J. Mamary Nathaniel Marchetti Parth Desai Kartik Shenoy J.L. Garfield John M. Travaline H. Criner S. Srivastava‐malhotra Vanna Tauch Roger A. Maxfield Keith Brenner William A. Bulman Beth Whippo Patricia Jellen Ravi Kalhan Colin T. Gillespie Sharon R Rosenberg Malcolm M. DeCamp A.S. Rogowski Juanita C. Hixon Luis F. Angel Osama Saber El Dib Frank C. Sciurba Divay Chandra Mateus Crespo Jessica Bon Field John Tedrow Carlos J. Ledezma Paula Consolaro Marie E. Beckner Adnan Majid Gillian Cheng José Cárdenas-García Douglas Beach Erik Folch A. Agnew Wataru Hori Arthur Nathanson Momen M. Wahidi Scott Shofer Matthew G. Hartwig

10.1016/j.chest.2019.02.012 article EN publisher-specific-oa CHEST Journal 2019-02-22

Background: In the United States, Pulmonary and Critical Care Medicine (PCCM) fellowship training traditionally requires performing a minimum number of bronchoscopy pleural procedures to be deemed competent. However, expert panel recommendations favor assessments based on skill knowledge. PCCM trainees have variable exposure advanced in presence interventional pulmonary (IP) fellowships, so we surveyed program directors (PD) across States assess procedural volume competency their fellows....

10.1097/lbr.0000000000001004 article EN cc-by-nc-nd Journal of Bronchology & Interventional Pulmonology 2025-02-10
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