Jose I. Nunez
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Cardiovascular Function and Risk Factors
- COVID-19 and healthcare impacts
- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- Congenital Heart Disease Studies
- Cardiac Ischemia and Reperfusion
- SARS-CoV-2 and COVID-19 Research
- Cardiac Imaging and Diagnostics
- Blood transfusion and management
- Health Systems, Economic Evaluations, Quality of Life
- Family and Patient Care in Intensive Care Units
- Acute Kidney Injury Research
- Viral Infections and Outbreaks Research
- Cardiac pacing and defibrillation studies
- Cardiovascular Effects of Exercise
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 and Mental Health
- Infective Endocarditis Diagnosis and Management
Albert Einstein College of Medicine
2021-2025
Montefiore Medical Center
2021-2025
Beth Israel Deaconess Medical Center
2020-2024
Hospital Clínico Universitario de Valencia
2024
University of Oxford
2021
Prince Charles Hospital
2021
Beth Israel Deaconess Hospital
2020
Dartmouth–Hitchcock Medical Center
2020
Universitat Politècnica de Catalunya
2018
Definitive guidelines for anticoagulation management during veno-venous extracorporeal membrane oxygenation (VV ECMO) are lacking, whereas bleeding complications continue to pose major challenges.
Mortality remains elevated during venoarterial extracorporeal membrane oxygenation support (VA-ECMO) for cardiogenic shock and the role of inflammation is uncertain. By using neutrophil-to-lymphocyte ratio (NLR), we investigated inflammatory dynamics VA-ECMO their relation to clinical outcomes. A single-center, retrospective cohort study was conducted. Patients receiving steroids or on-device less than 48 hours were excluded. grouped as those who did not have a persistent rise in NLR 24–48...
Abstract Background Heterogeneous respiratory system static compliance ( C RS ) values and levels of hypoxemia in patients with novel coronavirus disease (COVID-19) requiring mechanical ventilation have been reported previous small-case series or studies conducted at a national level. Methods We designed retrospective observational cohort study rapid data gathering from the international COVID-19 Critical Care Consortium to comprehensively describe —calculated as: tidal volume/[airway...
Division of Cardiology Department Medicine Montefiore Medical Center Albert Einstein College Bronx, New York
Abstract Background The role of neuromuscular blocking agents (NMBAs) in coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) is not fully elucidated. Therefore, we aimed to investigate COVID-19 patients with moderate-to-severe ARDS the impact early use NMBAs on 90-day mortality, through propensity score (PS) matching analysis. Methods We analyzed a convenience sample and ARDS, admitted 244 intensive care units within Critical Care Consortium, from February 1, 2020,...
Elevated right ventricular afterload following continuous-flow left assist device (CF-LVAD) may contribute to late heart failure (LRHF). PDE5i (phosphodiesterase-5 inhibitors) are used treat pulmonary hypertension and dysfunction after CF-LVAD, but their impact on outcomes is uncertain.
Abstract Background Despite contemporary management of ST-segment elevation myocardial infarction (STEMI) patients, cardiovascular death (CV death) and re-admission for acute heart failure (aHF) are frequent complications during follow-up. Several clinical, electrocardiographic, echocardiographic variables have been identified as risk factors major adverse events (MACE) in this setting. We aim to study the usefulness a score using universally available at discharge stratify MACE Methods...
Chronic heart failure -pathophysiology and mechanisms 1189for indexed LV mass, LA volume, mean E/e' systolic blood pressure (B=
Background: Insufficient left ventricular (LV) unloading during venoarterial extracorporeal life support (VA-ECLS) can result in poor LV recovery and inability to wean from support. Published data suggest a survival benefit with mechanical venting (MV), but there is limited comparing modalities. Methods: We queried the ELSO registry 2010-2019 for adults undergoing VA-ECLS MV stratified them by intra-aortic balloon pump (IABP) or percutaneous assist device (pVAD). excluded patients pulmonary...
Introduction: Venoarterial extracorporeal life support (VA-ECLS) imposes increased afterload on the left ventricle (LV), potentially provoking LV distension and impaired ventricular recovery. Prior studies have suggested a survival benefit with mechanical venting (MV), but multi-center data are lacking. Methods: We queried ELSO registry for adults undergoing VA-ECLS stratified them by use of MV, including intra-aortic balloon pump percutaneous assist device. excluded patients pulmonary...