Motohiro Asaki
A5043232317- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Family and Patient Care in Intensive Care Units
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Intravenous Infusion Technology and Safety
- Advanced MRI Techniques and Applications
- Viral Infections and Outbreaks Research
- COVID-19 diagnosis using AI
- Fuel Cells and Related Materials
- Sepsis Diagnosis and Treatment
- Acute Kidney Injury Research
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Patient Safety and Medication Errors
- Cardiac Imaging and Diagnostics
- Legionella and Acanthamoeba research
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Stroke Rehabilitation and Recovery
Fujieda Municipal General Hospital
2018-2024
Prince Charles Hospital
2021
Tokyo Metropolitan Tama Medical Center
2013-2016
Tokyo Metropolitan Hiroo Hospital
2016
Abstract The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases prospectively collected clinical data on people hospitalized with COVID-19. This was compiled during pandemic by a network hospitals that collect using ISARIC-World Health Organization Clinical Characterization Protocol tools. database includes from more than 705,000 patients, in 60 countries 1,500 centres worldwide. Patient are...
Abstract Background Heterogeneous respiratory system static compliance ( C RS ) values and levels of hypoxemia in patients with novel coronavirus disease (COVID-19) requiring mechanical ventilation have been reported previous small-case series or studies conducted at a national level. Methods We designed retrospective observational cohort study rapid data gathering from the international COVID-19 Critical Care Consortium to comprehensively describe —calculated as: tidal volume/[airway...
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is a global federation of clinical research networks that work collaboratively to prevent illness deaths from infectious disease outbreaks. In 2014, we proposed effective timely during outbreaks emerging infections would benefit pre-prepared tools, collaboration, research-ready networks.1 After applying this model several outbreaks, particularly the COVID-19 pandemic, can now explore what has been achieved date.
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) patients as one the most severe preventable complications COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right...
A 57-year-old man presented to the emergency department with fever and progressive altered level of consciousness 5 days’ duration. Three days before admission, influenza was diagnosed at a clinic. On his vital signs were unstable. Pneumonia through chest computed tomography, urinary Legionella antigen test positive. diagnosis septic shock due pneumonia made, critical care management initiated, including mechanical ventilation vasopressors. However, tachycardia did not improve, left...
Background: This study aimed to verify that the modified quick change (mQC) method of syringe exchange in critically ill patients receiving a continuous intravenous norepinephrine infusion is not inferior conventional double pumping (DP) method. Methods: non-blinded, quasi-randomized, non-inferiority trial was conducted single hospital from August 1, 2023 February 29, 2024. Adult aged 18 years or older who were admitted emergency ward and received eligible for inclusion. utilized convenience...
急性心筋炎の中には経過中に循環動態が破綻し致命的となる劇症型心筋炎が存在し，経皮的心肺補助装置（percutaneous cardiopulmonary support, PCPS）を導入して急性期をいかに乗り切れるかが重要となる。しかし，急性心筋炎自体が稀な疾患であり，治療成績を詳細に述べた報告は少ない。今回，当院で2003年4月から2013年11月までに経験した急性心筋炎18例について，年齢・性別・入院時バイタルサイン・入院時検査所見・入院後の治療法・院内予後について調査した。経過中に心原性ショックを呈した急性心筋炎8例中，循環動態破綻によりPCPSが必要と判断された劇症型心筋炎は6例であった。2例は来院直後に心停止に陥り，3例は来院後6時間以内に心原性ショックを呈した。1例は入院6日後に心原性ショックを呈した後に循環動態が破綻した。急性心筋炎のうち，入院後早期に心原性ショックに陥る症例はPCPSが必要となる可能性が高いと考えられた。
We describe a rare case of coronary spastic angina (CSA) causing myocardial stunning with reversible wall thinning and motion abnormality the left ventricle (LV). A 70-year-old woman presented sudden resting angina. 12-lead electrocardiogram showed typical ST-T changes acute infarction. Although ventriculography revealed akinesis from apex to mid-anterior LV, urgent angiography did not show an obstructed artery. Cardiac magnetic resonance imaging (MRI) identified anterior in akinetic region,...
症例は37歳，男性。幼少期に交通外傷により前頭葉壊死となり人格障害，症侯性てんかんで近医にて投薬を受けていた。搬送前日，数剤の抗てんかん薬を含む処方薬，約40日分を過量服薬し意識障害遷延のため翌日に当院へ救急搬送された。昏睡であり胃内容物吸引・挿管施行し，集中治療を開始した。第4病日の朝に全身痙攣と，多源性心室固有調律，心室頻拍を認めショック状態となった。直流通電や強心薬の投与開始で血圧は上昇したが，左室駆出率は30％，フェニトイン血中濃度は入院時の24.6μg/mLと比し40以上と高値を示し中毒の主体と考えた。その12時間後に再度ショック状態から難治性心停止となったため，veno arterial extracorporeal membrane oxygenation（VA-ECMO）を導入した。フェニトイン除去目的に活性炭による直接血液灌流法（direct hemoperfusion,...