Lukas Arenz
A5047775566- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Reproductive System and Pregnancy
- Sepsis Diagnosis and Treatment
- COVID-19 and Mental Health
- Immune cells in cancer
- Pneumonia and Respiratory Infections
- Thermal Regulation in Medicine
- Immune Response and Inflammation
- Viral Infections and Outbreaks Research
- Clinical Reasoning and Diagnostic Skills
- Ultrasound in Clinical Applications
- Vaccine Coverage and Hesitancy
- Antibiotic Use and Resistance
- Machine Learning in Healthcare
- HIV Research and Treatment
- COVID-19 diagnosis using AI
- Cardiac Arrest and Resuscitation
- Family and Patient Care in Intensive Care Units
- Emergency and Acute Care Studies
LMU Klinikum
2016-2024
Ludwig-Maximilians-Universität München
2022-2024
University of Oxford
2021
Prince Charles Hospital
2021
Abstract Background The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships age, sex, and nationality to presenting symptoms. Methods International, 60 109 symptomatic laboratory-confirmed COVID-19 recruited from 43 countries between 30 January 3 August 2020. Logistic regression was performed evaluate age sex published case definitions most commonly reported Results ‘Typical’ symptoms fever (69%), cough...
Different neurological manifestations of coronavirus disease 2019 (COVID-19) in adults and children their impact have not been well characterized. We aimed to determine the prevalence in-hospital complications among hospitalized COVID-19 patients ascertain differences between children. conducted a prospective multicentre observational study using International Severe Acute Respiratory emerging Infection Consortium (ISARIC) cohort across 1507 sites worldwide from 30 January 2020 25 May 2021....
Abstract The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) COVID-19 dataset is one of the largest international databases prospectively collected clinical data on people hospitalized with COVID-19. This was compiled during pandemic by a network hospitals that collect using ISARIC-World Health Organization Clinical Characterization Protocol tools. database includes from more than 705,000 patients, in 60 countries 1,500 centres worldwide. Patient are...
Abstract Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive (IMV). We aimed describe the clinical characteristics, outcomes and risk factors for failing support in treated severe during first two years pandemic high-income countries (HICs) low middle-income (LMICs). Methods This is a multinational, multicentre, prospective cohort study embedded...
Human myeloid-derived suppressor cells (MDSC) have been described as a group of immature myeloid which exert immunosuppressive action by inhibiting function T lymphocytes. While there is huge scientific interest to study these in multiple human diseases, the methodological approach varies substantially between published studies. This problematic MDSC seem be sensible cell type concerning not only cryopreservation but also time point after blood draw. To date data on delayed processing...
The International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) is a global federation of clinical research networks that work collaboratively to prevent illness deaths from infectious disease outbreaks. In 2014, we proposed effective timely during outbreaks emerging infections would benefit pre-prepared tools, collaboration, research-ready networks.1 After applying this model several outbreaks, particularly the COVID-19 pandemic, can now explore what has been achieved date.
Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining relationship between COVID-19 AKI low- low-middle income countries (LLMIC) are lacking. Given that is known to carry a higher mortality rate these countries, it important understand differences this population.
Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, possibly implementing clinical guidelines.
By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and methodological limitations. It is highly important to develop predictive tools for pulmonary embolism (PE) patients as one the most severe preventable complications COVID-19. Early recognition can help provide life-saving targeted anti-coagulation therapy right...
Objectives Point-of-care lung ultrasound (LU) is an established tool in the first assessment of patients with coronavirus disease (COVID-19). To assess progression or regression respiratory failure critically ill COVID-19 on Intensive Care Unit (ICU) by using LU. Materials and methods We analyzed all admitted to Internal Unit, Ludwig-Maximilians-University (LMU) Munich, from March 2020 December suffering caused severe acute syndrome 2 (SARS-CoV2). LU was performed according a standardized...
BackgroundIndividuals vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), when infected, can still develop disease that requires hospitalization. It remains unclear whether these patients differ from hospitalized unvaccinated with regard to presentation, coexisting comorbidities, and outcomes.MethodsHere, we use data an international consortium study this question assess differences between groups are context specific. Data 83,163 COVID-19 (34,843 vaccinated,...
Abstract Objectives To explore effectiveness and sustainability of guideline adherence antibiotic consumption after establishing treatment guidelines initiating antimicrobial stewardship (AMS) ward rounds in a university hospital emergency department (ED). Methods Data were gathered retrospectively from 2017 to 2021 the LMU University Hospital Munich, Germany. Four time periods compared: P1 (pre-intervention period); P2 (distribution pocket cards); P3 (reassessment 3 years); P4 (refresher...