Mário León Silva-Vergara

ORCID: 0000-0003-4296-9963
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About
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Research Areas
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • HIV-related health complications and treatments
  • Nail Diseases and Treatments
  • Research on Leishmaniasis Studies
  • Trypanosoma species research and implications
  • T-cell and Retrovirus Studies
  • Muscle metabolism and nutrition
  • Exercise and Physiological Responses
  • Cytomegalovirus and herpesvirus research
  • Plant Pathogens and Fungal Diseases
  • Science and Education Research
  • Nutrition and Health in Aging
  • Infectious Diseases and Mycology
  • Diabetes Management and Research
  • Reproductive tract infections research
  • Venomous Animal Envenomation and Studies
  • Rabies epidemiology and control
  • Women's cancer prevention and management
  • Coccidia and coccidiosis research
  • Iron Metabolism and Disorders
  • Folate and B Vitamins Research
  • Viral-associated cancers and disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Long-Term Effects of COVID-19

Universidade Federal do Triângulo Mineiro
2016-2025

Universidade Federal de Minas Gerais
2009

Instituto Federal de Educação, Ciência e Tecnologia do Triângulo Mineiro
1998

Universidade de Brasília
1995

Paracoccidioidomycosis is a systemic fungal disease occurring in Latin America that associated with rural environments and agricultural activities. However, the incidence prevalence of paracoccidiodomycosis underestimated because lack compulsory notification. If not diagnosed treated early adequately, endemic infection could result serious sequelae. While Paracoccidioides brasiliensis ( P. ) complex has been known to be causal agent paracoccidiodomycosis, new species, lutzii ), reported...

10.1590/0037-8682-0230-2017 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2017-07-12

Serologic tests have been widely used for the diagnosis of asymptomatic visceral leishmaniasis. This study evaluated five serologic infection: enzyme-linked immunosorbent assay (ELISA) using promastigote antigen (ELISAp), ELISA recombinant K39 (ELISA rK39), and K26 rK26) antigens, an indirect immunofluorescence test Leishmania (Leishmania) amazonensis (IIFT), immunochromatographic rK39 (TRALd). As a reference regarding performance tests, patients with classic leishmaniasis originating from...

10.4269/ajtmh.81.1.27 article EN American Journal of Tropical Medicine and Hygiene 2009-07-01

Paracoccidioides brasiliensis has rarely been isolated from its habitat in rural areas. In order to investigate the hypothesis that human infection with this fungus is linked coffee plantations (Coffea arabica), material was collected monthly over a period of 1 year farms town Ibiá, State Minas Gerais, Brazil. A total 760 samples soil, leaves and fruits cultured inoculated into mice. liver mouse soil showed temperature-dependent dimorphism vitro mycelium yeast phases characteristic P....

10.1080/02681219880000061 article EN Medical Mycology 1998-01-01

Abstract The purpose of this study is to analyse the effect 12 weeks non‐linear resistance training (NLRT) on anthropometry, muscle strength and inflammatory biomarkers in persons infected with human immunodeficiency virus (PIHIV). Thirty previously sedentary PIHIVs were randomized into NLRT ( n = 15) control (CON, groups. group submitted training, whereas CON maintained their daily habits. At baseline after weeks, both groups underwent anthropometric evaluations blood sampling for analysis...

10.1080/17461391.2016.1167962 article EN European Journal of Sport Science 2016-03-30

Natural infection of armadillos (Dasypus novemcinctus) with Paracoccidioides brasiliensis in Northern Brazil was reported 1986, raising great interest the understanding role this mammal epidemiological cycle fungus. Recently, P. isolated from soil Ibiá, State Minas Gerais, southeastern Brazil. Armadillos captured area were evaluated for presence viscera and detected 4/16 animals (25%). Fungal yeast phase cells observed three four infected by direct microscopic examination indirect...

10.1080/mmy.38.3.193.199 article EN Medical Mycology 2000-01-01

Background: Highly active antiretroviral therapy (HAART) is associated with high total cholesterol (TC), low-density lipoprotein (LDL-c), triglyceride (TG), and C-reactive protein (CRP) levels. The natural course of the HIV infection reduces high-density level (HDL-c). Thus, physical exercise plays a key role in reducing effects HAART HIV. Methods: Thirty people living (PLHIV) were randomized to nonlinear resistance training (NLRT) control (CON) groups. NLRT group underwent 12 weeks...

10.1123/jpah.2015-0540 article EN Journal of Physical Activity and Health 2016-02-19

ABSTRACT Purpose To evaluate the effects of combination exercise training (ET) and statins in people living with human immunodeficiency virus. Methods This was a randomized, double-blind, placebo-controlled clinical trial. Eighty-three virus were assigned to either placebo (PL), (STA), PL + ET (PLET) or STA (STAET) groups. Volunteers STAET groups administered 10 mg rosuvastatin, whereas PLET placebo. The performed three times week. Before after 12-wk follow-up, volunteers underwent...

10.1249/mss.0000000000002120 article EN Medicine & Science in Sports & Exercise 2019-08-06

The present open pilot study was conducted to assess the efficacy of azithromycin for treatment patients with cutaneous leishmaniasis in Araçuaí and Varzelândia, MG. Twenty-four less six months disease evolution were treated after clinical examination, Montenegro test a biopsy. schemes consisted oral doses 500 mg per day 3, 5 10 days 1000 two days. A control performed monthly cycles repeated when necessary until full reepithelialization lesions. On occasion final evaluation, 20 had completed...

10.1590/s0037-86822003000100010 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2003-01-01

We describe here the epidemiological and clinical characteristics of 10 HIV-infected patients with paracoccidioidomycosis. All were adult males from small towns in Brazil had a previous history work or residence rural area. The two infections diagnosed concomitantly six ten patients, for mycosis was first manifestation HIV infection. Risk factors infection injection drug use some multiple sexual partners others. Six died autopsy revealed severe disseminated paracoccidioidomycosis three....

10.1080/369378031000137215 article EN Medical Mycology 2003-01-01

To evaluate Cryptococcus spp. molecular types isolated from captive birds' droppings, an epidemiological survey was carried out in Uberaba, Minas Gerais, Brazil, December 2006 to September 2008. A total of 253 samples bird excreta (120 fresh and 133 dry) were collected pet shop cages houses different neighbourhoods. neoformans 19 (14.28%) dry one sample (0.84%). laurentii recovered seven (5.26%) samples, but not the samples. The canavanine-glycine-bromothymol blue test positive all C....

10.1111/j.1439-0507.2010.01901.x article EN Mycoses 2010-05-20

The aim of this study was to evaluate the effectiveness a 12-week nonlinear resistance training (NLRT) program on metabolic syndrome (MetS) components in people living with human immunodeficiency virus (PLHIV) and diagnosed MetS.Subjects were randomly assigned either NLRT (N.=10) or control (CON; N.=11) group. group exercised three times per week during 12 supervised program. CON asked maintain their daily habits. At baseline (pre) after intervention (post), both groups completed...

10.23736/s0022-4707.16.06294-0 article EN The Journal of Sports Medicine and Physical Fitness 2017-03-01

Paracoccidioidomycosis (PCM) is caused by dimorphic fungi from theParacoccidioides brasiliensis complex. Previous studies have demonstrated that the severity of disease associated with a T-helper 2 immune response characterised high interleukin (IL)-4 production. In present study we analysed two polymorphisms in IL-4 gene (-590 C/T and intron-3 microsatellite) 76 patients PCM 73 control subjects an endemic area. The production peripheral blood mononuclear cells after antigen or...

10.1590/0074-02760150197 article EN cc-by Memórias do Instituto Oswaldo Cruz 2015-09-01

Para caracterizar uma área endêmica de leishmaniose tegumentar americana susceptível intervenção com candidato à vacina anti-leishmania, foi iniciado em 1999 estudo longitudinal rural do Município Varzelândia, Minas Gerais, Brasil. Inicialmente, foram cadastrados 1.253 indivíduos distribuídos 246 domicílios, dos quais, 1.170 concordaram participar trabalho. Desses, 593 (50,6%) eram masculinos e 662 (56,5%), menores 21 anos. A intradermorreação Montenegro realizada 1.120 indivíduos, lida...

10.1590/s0102-311x2006000600023 article PT cc-by Cadernos de Saúde Pública 2006-06-01

A non-randomized controlled clinical trial was carried outin order to evaluate both azithromycin and antimony efficacy in cutaneous leishmaniasis Manaus, AM, Brazil. Forty nine patients from genders, aged 14 70, with ulcers for less than three months a positive imprint Leishmania spp. amastigotes were recruited into two groups. Group I (26 patients) received daily-single oral dose of 500 mg 20 days II (23 intramuscular mg/kg meglumine antimony, also days. Azithromycin cured 24 (12.5%) on 60,...

10.1590/s0036-46652008000300005 article EN Revista do Instituto de Medicina Tropical de São Paulo 2008-06-01

Natural infection of armadillos (Dasypus novemcinctus) with Paracoccidioides brasiliensis in Northern Brazil was reported 1986, raising great interest the understanding role this mammal epidemiological cycle fungus. Recently, P. isolated from soil Ibiá, State Minas Gerais, southeastern Brazil. Armadillos captured area were evaluated for presence viscera and detected 4/16 animals (25%). Fungal yeast phase cells observed three four infected by direct microscopic examination indirect...

10.1080/714030937 article EN Medical Mycology 2000-06-01

Abstract The objective of the present study was to assess infections and cytologic abnormalities in cervicovaginal smears from 153 HIV‐positive women 169 HIV‐negative followed up at UFTM School Medicine between May 1999 2002. medical records were reviewed group classified according CD4 cell count, HIV viral load, antiretroviral therapy subgroups (with or without disease; with therapy) compared group. We conclude that frequency Candida sp, Trichomonas vaginalis bacterial vaginosis smear, is...

10.1002/dc.20892 article EN Diagnostic Cytopathology 2009-01-23

An open trial to evaluate the azithromycin efficacy in cutaneous leishmaniasis patients was carried out Manaus (AM), where Leishmania (Viannia) guyanensis is main etiologic agent. Forty-one with skin lesions of less than 12 weeks duration, without specific treatment for last three months and a positive imprint sp. were included. From these, 31 (75.6%) male median age 30.2. All them received daily-single oral dose 500 mg ten days. At 25th day, 16 (39%) presented therapeutic failure...

10.1590/s0036-46652007000400008 article EN Revista do Instituto de Medicina Tropical de São Paulo 2007-08-01

Descreve-se a presença de cistos unizóicos Isospora belli em linfonodos mesentéricos e gametócitos no epitélio da vesícula biliar um paciente brasileiro 26 anos idade, com Síndrome Imunodeficiência Adquirida que recebeu tratamento, por diversas vezes, sulfametoxazol-trimetoprim. Discute-se importância dos teciduais I. como possíveis focos resistência do parasita associação destes episódios recidivas infecção mesmo após tratamento medicação anticoccídios.

10.1590/s0037-86822003000300014 article PT cc-by Revista da Sociedade Brasileira de Medicina Tropical 2003-06-01
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