- Bariatric Surgery and Outcomes
- Gestational Diabetes Research and Management
- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Adrenal and Paraganglionic Tumors
- Clinical Nutrition and Gastroenterology
- Metabolism, Diabetes, and Cancer
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Management and Research
- Pituitary Gland Disorders and Treatments
- HIV-related health complications and treatments
- Cancer, Hypoxia, and Metabolism
- Pregnancy and preeclampsia studies
- Pancreatic function and diabetes
- Muscle metabolism and nutrition
St. Marianna University School of Medicine
2018-2024
Yokohama City Seibu Hospital
2023-2024
Type 2 diabetes is associated with sarcopenia. Resistance training and appropriate nutritional therapy are reported to be effective for muscle strength mass. This study aimed evaluate the effect of resistance using elastic bands at home combined a leucine-rich amino acid supplement on strength, physical function, mass in elderly type diabetes. We conducted 48-week prospective single-center randomized controlled trial 60 patients who were randomly allocated one three groups: control (C),...
This study assessed the association of muscle mass with insulin resistance, evaluated from sensitivity index (ISI), in Japanese patients gestational diabetes mellitus (GDM). Consecutive GDM (n = 96) admitted to St. Marianna University Hospital between October 2015 and March 2018 for initial education glycemic control were enrolled a prospective observational study. Insulin resistance was by measuring ISI body composition bioelectrical impedance analysis. The subjects aged 34.4 ± 4.8 years...
We previously reported changes of body composition determined by dual-energy X-ray absorptiometry after treatment with ipragliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. In that study, mean weight was decreased 3.5 kg (4.3% the baseline value) ipragliflozin at 50 mg/day, fat mass and lean showing similar reductions 1.7 1.8 kg, respectively. A long-term decrease in patients treated SGLT2 inhibitors may be associated loss skeletal muscle, which could potentially have an impact...
Adrenocortical carcinoma (ACC) patients with glucocorticoid excess have been reported to be associated decreased tumor-infiltrating immune cells, but the effects of in situ production on tumor immunity remained unknown. In addition, ACC was also known harbor marked intra-tumoral heterogeneity steroidogenesis or disorganized steroidogenesis. Therefore, this study, we immune-profiled lymphocytes (TILs) and tumor-associated macrophages (TAMs) pivotal steroidogenic enzymes biosynthesis (CYP17A...
Abstract Background Diabetes treatment aims to prevent complications and help patients lead a healthy life comparable individuals without diabetes. The age at death of with diabetes has been reported be lower than that those Therefore, we aimed analyze the differences in cause between Methods We retrospectively analyzed 9,627 adult who died St. Marianna University Hospital (Kawasaki, Japan) using electronic medical record data collected January 2011 December 2020. extracted on sex, death,...