- Dermatology and Skin Diseases
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Dermatological diseases and infestations
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Occupational exposure and asthma
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Drug-Induced Adverse Reactions
- SARS-CoV-2 and COVID-19 Research
- melanin and skin pigmentation
- IL-33, ST2, and ILC Pathways
- Dermatological and COVID-19 studies
- Genetic and rare skin diseases.
- Health and Medical Studies
- Insects and Parasite Interactions
- Complementary and Alternative Medicine Studies
- Historical Medical Research and Treatments
- Inflammasome and immune disorders
- Acne and Rosacea Treatments and Effects
- Histiocytic Disorders and Treatments
- Skin Protection and Aging
- Hidradenitis Suppurativa and Treatments
Ghent University Hospital
2015-2024
University of Brescia
2024
Ghent University
2007-2019
Prurigo nodularis is a chronic, debilitating, and severely pruritic neuroimmunologic skin disease. Nemolizumab, an interleukin-31 receptor alpha antagonist, down-regulates key pathways in the pathogenesis of prurigo nodularis. Download PDF Research Summary. In this phase 3, double-blind, multicenter, randomized trial, we assigned adults with moderate-to-severe to receive initial 60-mg dose nemolizumab followed by subcutaneous injections 30 mg or 60 (depending on baseline weight) every 4...
<b><i>Background:</i></b> Allergic rhinitis (AR) is the most common allergic disorder and its prevalence has significantly increased worldwide, nowadays affecting up to 40% of population in young adults. The objective present survey was evaluate sensitization clinically diagnosed AR a sample Belgian population, estimate effect age gender. <b><i>Methods:</i></b> We performed cross-sectional population-based study at an annual public fair Ghent....
Summary Background The rate of contact allergy and allergic dermatitis caused by methylisothiazolinone ( MI ) is dramatically increasing throughout E urope. Objectives To report on methylchloroisothiazolinone MCI )/ in B elgium. Patients methods Between J anuary 2010 D ecember 2012, the medical charts 6599 patients elgian C ontact nvironmental ermatitis G roup were retrospectively reviewed for / sensitization use a standardized questionnaire. Available data 2081 tested 2013 also included....
Abstract Background Real‐world evidence describing the benefits of recommended therapies and their impact on quality life (QoL) chronic urticaria (CU) patients is limited. Objective To investigate disease burden, current treatment schedule, use clinical resources by with H 1 ‐antihistamine‐refractory CU in Europe. Methods AWARE (A World‐wide Antihistamine‐Refractory patient Evaluation) a global, prospective, non‐interventional study real‐world setting, sponsored manufacturer omalizumab....
Background Global chronic urticaria (CU) disease experience and management is not well documented. This study descriptively compares these aspects among CU patients residing in Europe (EU) Central South America (C/SA).Methods AWARE (A World-wide Antihistamine-Refractory patient Evaluation) a global prospective, non-interventional of the real-world setting. Patients were ≥ 18 years with diagnosis H1-antihistamine-refractory for > 2 months. Differences between EU C/SA regions demographic...
Expert opinion: defining response to omalizumab in patients with chronic spontaneous urticariaOmalizumab (a recombinant, humanized anti-immunoglobulin-E antibody) has been shown three pivotal Phase III trials (ASTERIA I, II and GLACIAL) real-world studies be effective well-tolerated for the treatment of urticaria (CSU), is only licensed third-line CSU.However, definition often differs between clinical trials, studies, daily practice individual physicians globally.As such, a consensus...
Self-reported penicillin allergy in patients the Surgical Day Hospital: prevalence, impact and consequences Objective: Penicillin is a prevalent global issue, affecting approximately 2-12% of population. However, studies indicate that up to 90% individuals labeled as penicillin-allergic can tolerate penicillins. Consequently, often receive less effective antibiotics, leading increased rates surgical site infections. Design: This study aims assess prevalence self-reported allergy. Secondary...
In 2015 and 2016, female patients in Flanders consulted a dermatologist because they developed skin lesions after wearing specific brand of canvas shoes.To identify the culprit allergen shoes.Eighteen young females aged 14-22 years presented with itching erythematous to purple-coloured eczematous on both feet. They were patch tested by 10 dermatologists European baseline series. Some underwent testing additional Pieces shoe fabrics 11 18 patients. Chemical analysis materials was performed....
Postoperative scarring is a common cause of patient dissatisfaction. Several strategies have been developed to improve its clinical aspects.To assess efficacy and safety the 10,600 nm ablative fractional carbon dioxide (CO2) laser in treatment recent surgical scars head neck region.A prospective, randomized, single-blind intrapatient controlled study was conducted on 9 postoperative region. On half scar, 3 sessions were performed. Physician/Patient Global Assessment (PhGA/PGA) Patient...
Summary Background Anti‐vascular endothelial growth factor ( VEGF ) medication, injected intravitreally, is currently the standard of care in patients with different retinal pathologies. Since its introduction 2006, an increasing number have undergone this procedure Ghent University Hospital. Strikingly, more were diagnosed contact dermatitis caused by ophthalmic products used during intravitreal injection procedure. Objectives To identify which substances most likely to cause dermatitis....
Abstract Background Chronic spontaneous urticaria (CSU) is characterized by the repeated occurrence of persistent hives and/or angioedema for ≥6 weeks, without specific external stimuli. H 1 ‐antihistamines have long been standard care CSU, but many patients remain uncontrolled even at 4× approved dose. Add‐on therapy with omalizumab has proven effective in clinical trials, little known about treatment Belgium. Objective To collect real‐world data on adults CSU Methods This was an...
Abstract Background Evidence on the (long‐term) safety of systemic immunomodulating therapies in atopic dermatitis (AD) generated by real‐world data is sparse. Objectives To describe reported adverse drug reactions (AEs) related to therapy patients with AD and compare incidence rates AEs Summaries Product Characteristics (SmPCs). Methods We conducted an observational prospective multi‐centre cohort study, using TREAT NL registry. All severe AEs, special interest serious adult paediatric...
Aims and Objectives. The aim of this paper was to illustrate the socially inclusive nature Bug Busting ‘whole‐school approach’ head louse eradication. Background. In UK, Belgium Denmark, persistent lice in families all socio‐economic status (SES) is a problem. Since 1995 UK 1998 elsewhere, an educational programme intended teach how detect treat by using wet combing method has been organized some areas. Local schools lead community strategy for prevention, known as (UK). Design methods. We...
Summary Background During rubber vulcanization, new compounds can be formed. Objectives To report a case of allergic shoe dermatitis in which the search for allergen ultimately led to identification dimethylthiocarbamylbenzothiazole sulfide (DMTBS) . Methods A female presented with eczema on her feet after wearing S perry T op ider® canvas sneakers. Patch testing was performed E uropean baseline series, additional materials, and extracts materials. Thin‐layer chromatography ( TLC ) patch...