To investigate the effects of using different filters in continuous renal replacement therapy (CRRT) on mortality, inflammatory mediator level and hemodynamics patients with sepsis-associated acute kidney injury (SA-AKI). A prospective study was conducted. The SA-AKI undergoing first CRRT admitted to critical care medicine department General Hospital Ningxia Medical University from August 2022 October 2023 were enrolled as objects, they divided into observation group control by random number...

To investigate the predictive value of inflammatory indicator and serum cystatin C (Cys C) for prognosis patients with sepsis-associated acute kidney injury (SA-AKI). A prospective observational study was conducted. Patients SA-AKI admitted to intensive care unit (ICU) General Hospital Ningxia Medical University from January 2022 December 2023 were selected as subjects. patient data, sequential organ failure assessment (SOFA), physiology chronic health evaluation II (APACHE II), indicator,...

Application values of thromboelastography (TEG) in dynamic monitoring coagulation parameters sepsis patients were investigated. Eighty-one with who admitted to the ICU department General Hospital Ningxia Medical University from April 1, 2015 December 31, collected. Clinical data Data compared using 5 grouping methods: i) 81 divided into group (n=45) and shock (n=36); ii) two groups: A (APACHE II score ≤13, n=51); B >13, n=30); iii) according Disseminated Intravascular Coagulation Diagnosis...

Current studies on CD62P have focused mainly cardiovascular diseases, while only few evaluated the effects of development sepsis and association between endothelial cell injury with inflammation coagulation. This study attended to explore coagulation by evaluating expression soluble (s-CD62P) in plasma its mechanism patients sepsis, thus provide evidence effective treatment anti-adhesion therapy targeted CD62P.A total 70 critically ill systemic inflammatory response syndrome (SIRS) admitted...

Reducing inflammation can effectively relieve acute lung injury (ALI). Objective . To test whether keratinocyte growth factor‐2 (KGF‐2) reduce oleic acid‐induced in ALI of rats and explore its possible mechanism. Methods 45 Sprague‐Dawley were randomly divided into control group, + KGF‐2 group. The animal model was established by injecting 0.1 mL/kg acid the tail vein rats. Rats group injected with equal volume normal saline (NS). Each needs pretreatment 72 hours before preparation model....

The aim of this study was to examine the role keratinocyte growth factor-2 (KGF-2) in oleic acid-induced acute lung injury (ALI) rats. Forty-five healthy adult male Sprague Dawley rats were divided into 3 groups. Rat ALI model established by injection 0.01 mL/kg acid tail vein. Rats control group injected with same amount normal saline (NS). In + KGF-2 group, 5 mg/kg instilled airway 72 hours before preparation, and NS. permeability index (LPI) wet/dry weight (W / D) ratios measured 8 after...

OBJECTIVE To observe the effect of dexmedetomidine (DEX) on expression tight junction protein ZO-1 in kidney tissues rats with acute injury (AKI) induced by sepsis. METHODS Sixty healthy male Sprague-Dawley were selected and divided into four groups: sham operation group (Sham group), DEX + Sham group, cecal ligation puncture (CLP) CLP according to a random number table, 15 each group. Each was then 3 subgroups at 6, 12, 24 hours after operation, 5 subgroup. Modified used establish sepsis...

Objective To compare the measured resting energy expenditure (MREE) in patients with sepsis calculated using respiratory indirect calorimetry and Harris-Benedict (HB) coefficient method, to investigate influence of different target on prognosis sepsis. Methods This was a prospective comparative study. 60 who were suitable for nutrition support Intensive Care Unit (ICU) General Hospital Ningxia Medical University from January October 2015 selected. (1)MREE simultaneously HB...

To investigate the value of renal artery resistance index (RRI) and urinary angiotensinogen (UAGT) in early diagnosis acute kidney injury (AKI) patients with sepsis.A prospective study was conducted. Seventy-eight sepsis admitted to department critical care medicine General Hospital Ningxia Medical University from January September 2021 were enrolled. Patients observed for development AKI within 1 week. data [gender, age, body mass (BMI), major infection sites illness related scores],...

Objective To investigate the effects of traditional Chinese medicine colquhounia root tablet on expression tight junction protein claudin-2 and ZO-1 in bronchial epithelium tissues rats with acute lung injury (ALI), to study mechanism protective effect ALI. Methods Twenty-four healthy male Sprague-Dawley (SD) were randomly divided into control group, ALI group pretreatment 8 each group. The model was reproduced by intravenous injection oleic acid 0.04 mL/kg, given same amount normal...

Objective To evaluate the effect of colquhounia root tablet on expression tight junction proteins claudin-5 and ZO-1 in renal tissues rats with acute lung injury (ALI). Methods Twenty-four healthy male Sprague-Dawley rats, weighing 250-300 g, were randomly divided into 3 groups (n = 8 each) using a random number table: control group (group C), ALI group; H). Oleic acid 0.04 ml/kg was injected trail vein to establish model ALI.In H, 600 mg·kg-1·d-1 instilled stomach each rat for 10...

Objective To observe the clinical findings about endothelial cell injury related to genesis of inflammatory cytokines and coagulation.Methods A total 70 critically ill patients with SIRS (systemic response syndrome) admitted intensive care unit (ICU) between September 2009 February 2010 were enrolled for a prospective control study.According diagnostic criteria Sepsis/SIRS,the divided into two groups:sepsis group (n =38) =32),and another 20 healthy volunteers served as group.Patients in...

To observe the effects of keratinocyte growth factor-2 (KGF-2) on expressions chemokine FKN and tight junction protein claudin-5 in lung tissue rats with acute injury (ALI).Healthy male Sprague-Dawley (SD) were randomly divided into normal saline (NS) control group, ALI model group KGF-2 pretreatment 10 each group. The rat was reproduced by injection 0.01 mL/kg oleic acid tail vein, NS injected same amount NS. instilled 5 mg/kg airway at 72 hours before reproduction, abdominal aortic blood...

To evaluate the difference and correlation of 24-hour energy expenditure in patients with multiple trauma receiving mechanical ventilation predicted by indirect calorimetry (IC) HB formula.140 admitted to intensive care unit (ICU) General Hospital Ningxia Medical University from December 1st, 2016 August 31st, 2017 were enrolled. The was repeatedly measured at 1, 3, 5, 7 days after ICU admission IC method, method used as "gold standard" calculate kilogram body weight expenditure. value...

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