A5101684987- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Sepsis Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Hemodynamic Monitoring and Therapy
- Tracheal and airway disorders
- Colorectal Cancer Surgical Treatments
- Cardiac Imaging and Diagnostics
- Trauma Management and Diagnosis
- Congenital Heart Disease Studies
- Ureteral procedures and complications
- Urological Disorders and Treatments
- Thermal Regulation in Medicine
- Organ and Tissue Transplantation Research
- Renal and Vascular Pathologies
- Bladder and Urothelial Cancer Treatments
- Surgical Simulation and Training
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Transplantation: Methods and Outcomes
- Head and Neck Surgical Oncology
Baylor College of Medicine
2024-2025
Texas Children's Hospital
2024-2025
Centre Hospitalier Universitaire Amiens-Picardie
2023-2024
University of Copenhagen
2023
Rigshospitalet
2023
Medizinische Hochschule Brandenburg Theodor Fontane
2022
Universitätsmedizin Göttingen
2022
Malteser-Krankenhaus
2019
University of Applied Sciences Landshut
2013-2017
University Hospital Münster
1981-2016
Background: Whole body hyperthermia induced by radiative systems has been used in therapy of malignant diseases for more than ten years.Von Ardenne and co-workers have developed the 'systemiche Krebs-Mehrschritt-Therapic' (sKMT), a combined regime including whole 42°C, hyperglycaemia relative hyperoxaemia with additional application chemotherapy.This concept employed phase I/II clinical study patients metastatic colorectal carcinoma at Virchow-Klinikum since January 1997.Methods: The sKMT...
The amount of procalcitonin eliminated in the urine and plasma disappearance rate were evaluated patients with normal impaired renal function, because sepsis are a main target group for measurement, these often develop dysfunction.Elimination (microgram 12 h-1) was measured 76 patients. In another 67 patients, 50% (t1/2, h) 48 h after peak concentrations (procalcitonin > 2 micrograms L-1). Renal function assessed by creatinine clearance.Procalcitonin elimination significantly reduced severe...
Summary Background and objective The amount of procalcitonin eliminated in the urine plasma disappearance rate were evaluated patients with normal impaired renal function, because sepsis are a main target group for measurement, these often develop dysfunction. Methods Elimination (µg 12 h−1) was measured 76 patients. In another 67 patients, 50% (t½, h) 48 h after peak concentrations (procalcitonin > 2 µg L−1). Renal function assessed by creatinine clearance. Results Procalcitonin elimination...
Intestinal manipulation triggers an inflammatory cascade within the muscularis causing postoperative ileus (POI). The aim of this study was to investigate recovery and therapeutic potential interleukin 10 (IL10) for POI.POI induced by bowel surgical (SM) in wild-type, IL10(-/-) recombinant murine IL10 (rmIL10)-treated mice. Immunohistochemistry localised externa, histochemistry quantified neutrophil recruitment, quantitative PCR alterations mRNA. Luminex multiplex analysis, Griess reaction...
During Gram-negative bacterial infections, lipopolysaccharide (LPS) interacts with monocyte/macrophage receptors, resulting in a host defense response. Activation of intracellular signal transduction pathways implicating various protein kinase and phospholipases is crucial activating the transcription genes encoding proinflammatory cytokines inducible nitric oxide synthase (iNOS). In this article, we demonstrate that mouse, endotoxin shock activation phosphatidylcholine-specific...
<i>Background/Aims:</i> Warm ischemia to liver with subsequent Kupffer cell-dependent pathology is associated many clinical conditions. Taurine prevents cell activation and improves graft survival after experimental cold transplantation. Thus this study was designed assess its effects warm hepatic ischemia. <i>Methods:</i> The left lobe of female Sprague-Dawley rats (170–210 g) underwent 60 min Animals were given either intravenous taurine or Ringer’s solution 10...
Small-animal intubation is often necessary during inhalation anesthesia to allow steady-state conditions for large operations and in vivo experiments all fields of experimental surgery. In rats, placing an orotracheal tube technically difficult primarily because the small size subject lack equipment specifically designed this task. We describe a simple rat technique which animal suspended dorsal recumbency on inclined metal plate. The animal, anesthetized with ether, fixed 70...