- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Bone Tissue Engineering Materials
- Acute Myocardial Infarction Research
- Cancer, Hypoxia, and Metabolism
- Cancer Research and Treatments
- Neonatal and fetal brain pathology
- Immunotherapy and Immune Responses
- Dental Research and COVID-19
- Angiogenesis and VEGF in Cancer
- Neonatal Respiratory Health Research
- Orthopaedic implants and arthroplasty
- Zebrafish Biomedical Research Applications
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Immune cells in cancer
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Traditional Chinese Medicine Analysis
- Coronary Interventions and Diagnostics
- Endodontics and Root Canal Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Advanced Glycation End Products research
Sichuan University
2014-2025
North China University of Science and Technology
2021-2025
Nanjing University of Chinese Medicine
2024-2025
Feed Research Institute
2025
Chinese Academy of Agricultural Sciences
2025
Ministry of Agriculture and Rural Affairs
2025
State Key Laboratory of Oral Diseases
2018-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2024
Binzhou Medical University
2019-2024
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2024
Tumor neovascularization is a highly complex process including multiple steps. Understanding this process, especially the initial stage, has been limited by difficulties of real-time visualizing embedded in tumor tissues living animal models. In present study, we have established xenograft model zebrafish implanting mammalian cells into perivitelline space 48 hours old Tg(Flk1:EGFP) transgenic embryos. With model, dynamically visualized neovascularization, with unprecedented high-resolution,...
By removing a part of the structure, tooth preparation provides restorative space, bonding surface, and finish line for various restorations on abutment. Preparation technique plays critical role in achieving optimal result preparation. With successful application microscope endodontics >30 years, there is full expectation microscopic dentistry. However, as relatively little progress has been made dentistry prosthodontics, following assumptions have proposed: Is it suitable to choose under...
Hypertension is not merely a vascular disorder but significant risk factor for neural impairment. Moreover, healthcare the hypertensive population with environmental or occupational pollutants has become an issue of increasing concern in public health. As traditional neurotoxic heavy metal, Pb exposure results neuroinflammation as well neurodegenerative diseases. The current study aimed to investigate mechanisms mice exposed Pb. We demonstrated that hypertension exacerbated Pb-induced...
The function of albumin in the movement cholesterol into and out non-cholesterol-loaded fibroblasts has been investigated. Cholesterol efflux from cholesterol-labeled normal human skin to fatty acid-free serum (HSA) is biphasic with a rapid first phase that plateaus at about 15 min followed by nearly linear up 90 min, longest incubation this study. Saturation observed 10 mg albumin/mL. Efflux specific since other molecules, such as ovalbumin or gelatin, do not induce efflux. ability HSA...
The lung squamous cell carcinoma survival rate is very poor despite multimodal treatment. It urgent to discover novel candidate biomarkers for prognostic assessment and therapeutic targets (SCC).Herein a two-dimensional gel electrophoresis ESI-Q-TOF MS/MS-based proteomic approach was used identify differentially expressed proteins between SCC adjacent normal tissues. 31 with significant alteration were identified. These mainly involved in metabolism, calcium ion binding, signal transduction...
Lung cancer is the leading cause of cancer-related death in world. Non-small cell lung carcinomas (Non-SCLC) account for almost 80% cancers, which 40% were adenocarcinomas. For a better understanding molecular mechanisms behind development and progression cancer, particularly adenocarcinoma, we have used proteomics technology to search candidate prognostic therapeutic targets pulmonary adenocarcinoma. The protein profile changes between human adenocarcinoma tissue paired surrounding normal...
To evaluate physicians' current practice, attitudes toward, and knowledge of cancer pain management in China.We conducted a face-to-face survey physicians (oncologists, internists, hematologists) who are responsible for the care patient 11 general hospitals Sichuan, China between December 2011 2013. Statistical analyses were performed using SPSS (SPSS, Chicago, IL) software.A 23-item questionnaire was designed distributed to 550 medical facilities China.Five hundred (90.90%) responded. About...
Glioblastoma multiforme (GBM) is characterized by extensive endothelial hyperplasia. Recent studies suggest that a subpopulation of cells originates via vasculogenesis the transdifferentiation GBM tumor into (endo-transdifferentiation). The molecular mechanism underlying this process remains poorly defined. Here, we show expression ETS variant 2 (ETV2), master regulator cell development, highly correlated with malignancy. Functional demonstrate ETV2 sufficient and necessary for...
The early weaning of lambs frequently leads to weakened immunity, impaired intestinal function, and increased susceptibility disease. Lactobacillus plays a role in regulating enhancing antioxidant capacity, maintaining health. This study aims isolate strain with favorable probiotic properties from sheep feces investigate its effects on the health early-weaned lambs. In this study, growth characteristics, acid production bacteriostatic bile salt tolerance, gastrointestinal fluid...
Purpose This study aims to investigate whether innovation culture drives enterprise digital transformation and identifies its indirect impacts. Design/methodology/approach The research samples comprise A-share listed enterprises from Shanghai Shenzhen between 2011 2023. Text analysis machine learning are used measure culture. Baseline regression, mediation effect moderating models constructed through OLS regression examine the impact of on verify hypotheses. Findings findings reveal that...
Abstract Predicting repetitive transcranial magnetic stimulation (rTMS) effects on whole-brain dynamics in clinical populations is crucial for developing personalized therapies and advancing precision medicine brain disorders. This study provides the first proof-of-concept demonstrating that Digital Twin Brain (DTB) can forecast rTMS state individuals with disorders (chronic tinnitus). First, we identified two aberrant states predominantly overlapped somatomotor default mode networks,...
Objective . To evaluate the influence of screw‐tightening methods on immediate and long‐term stability dental implant screw joints. Methodology A total 150 implants three different systems with diameters were used in this study. Each group was divided into subgroups ( n = 5), according to tightening (A—tightening recommended torque retorque after 10 min; B—tightening torque, then loosening retorque; C—tightening only once). The operating time assemblies recorded. Ten minutes later, removal...
Polyetherketoneketone (PEKK), a high-performance thermoplastic special engineering material, maintains bone-like mechanical properties and has received considerable attention in the biomedical field. The 3D printing technique enables production of porous scaffolds with honeycomb structure featuring precisely controlled pore size, porosity interconnectivity, which holds significant potential for applications tissue engineering. ideal architecture PEKK yet to be elucidated. Porous five sizes...