A5029199635- Traumatic Brain Injury Research
- Language, Metaphor, and Cognition
- EEG and Brain-Computer Interfaces
- Syntax, Semantics, Linguistic Variation
- Psychosomatic Disorders and Their Treatments
- linguistics and terminology studies
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Lexicography and Language Studies
- Categorization, perception, and language
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Language, Discourse, Communication Strategies
- Neuroscience and Music Perception
- Neural dynamics and brain function
- Neurobiology of Language and Bilingualism
- Epilepsy research and treatment
- Action Observation and Synchronization
- Neurological disorders and treatments
- Sleep and Wakefulness Research
- Cognitive Functions and Memory
- Music Therapy and Health
- Healthcare Decision-Making and Restraints
- Historical Linguistics and Language Studies
- Diverse Music Education Insights
University of Birmingham
2015-2024
Western University
2011-2023
MRC Cognition and Brain Sciences Unit
2010-2012
Medical Research Council
2010-2012
University of Cambridge
2011-2012
Cardiff University
2009-2011
University of Manchester
1976-2004
Institut de Recherche en Informatique de Toulouse
1995
Bangor University
1994
Functional connectivity in the default mode network (DMN) is known to be reduced patients with disorders of consciousness, a different extent depending on their clinical severity. Nevertheless, integrity structural architecture supporting this and its relation exhibited functional disconnections are very poorly understood. We investigated white matter DMN consciousness varying severity.Fifty-two patients--19 vegetative state (VS), 27 minimally conscious (MCS), 6 emerging from (EMCS)--and 23...
Mainstream linguists have now begun to take an interest in the way formal resources of language are put use by people communicative situations. A powerful impulse for this awakening came from Grice's paper ‘The logic conversation’; (1975). work has he examined, criticized, and developed (see, example, Wilson, 1975; Kempson, 5975), prospects emerging a much more satisfying comprehensive picture at setting. The present is intended as contribution developing field.
The term ‘agentive’ is a familiar one in current discussions of the syntax English (and other languages). Although most who use it seem, at first glance, to be referring more or less same semantic feature, employed variety ways. For instance, Fillmore (1968: 24) talks an ‘agentive case’; Gruber (1967: 943) has verbs’; Lyons and others speak nouns’; while Halliday 196), although he does not ‘agentive’, distinguishes feature clauses which clearly related notion agentivity. Apart from this...
This is a clear and handy reference book for those beginning the study of semantics or pragmatics. alphabetic guide introduces terms referring to key concepts in The meaning as it conveyed through language - domain pragmatics one central concerns linguistics, its importance cannot be exaggerated. Written by an author well-known field semantics, glossary provides accessible explanations drawn from wide range theoretical approaches.
The expression is part of can be used in a number different senses. One might cite as examples:A sheep flock. A priest the clergy. Changing nappies being mother.A petal flower. But one does not ask What are parts clergy? or mother? flower? human body? I shall refer to latter ‘structural parts’, distinguish them from rest; it with relation between structural and their wholes that present paper will concerned. This also expressed by sentences form flower has petals, body arms , etc. (The verb...
Patients in the Vegetative State (VS) do not produce overt motor behavior to command and are therefore considered be unaware of themselves their environments. However, we recently showed that high-density electroencephalography (EEG) can used detect covert command-following some VS patients. Due its portability inexpensiveness, EEG assessments awareness have potential contribute a standard clinical protocol, thus improving diagnostic accuracy. this technique requires refinement optimization...
Heart rate has natural fluctuations that are typically ascribed to autonomic function. Recent evidence suggests conscious processing can affect the timing of heartbeat. We hypothesized heart is modulated by and therefore dependent on attentional focus. To test this, we leverage observation neural processes synchronize between subjects presenting an identical narrative stimulus. As predicted, find significant inter-subject correlation (ISC-HR) when presented with auditory or audiovisual...
There is growing awareness across the neuroscience community that replicability of findings about relationship between brain activity and cognitive phenomena can be improved by conducting studies with high statistical power adhere to well-defined standardised analysis pipelines. Inspired recent efforts from psychological sciences, desire examine some foundational using electroencephalography (EEG), we have launched #EEGManyLabs, a large-scale international collaborative replication effort....
Functional neuroimaging has shown that the absence of externally observable signs consciousness and cognition in severely brain-injured patients does not necessarily indicate true such abilities. However, relative to traumatic brain injury, nontraumatic injury is known be associated with a reduced likelihood regaining overtly measurable levels consciousness. We investigated relationships between etiology both overt covert cognitive abilities group minimally conscious state (MCS).Twenty-three...
Minimal or inconsistent behavioural responses to command make it challenging accurately diagnose the level of awareness a patient with Disorder Consciousness (DOC). By identifying markers mental imagery being covertly performed command, functional neuroimaging (fMRI, EEG) has shown that some these patients are aware despite their lack responsiveness. We report findings behavioural, fMRI, and EEG approaches detecting command-following in group DOC. From an initial sample 14 patients, complete...
Patients with traumatic brain injury who fail to obey commands after sedation-washout pose one of the most significant challenges for neurological prognostication. Reducing prognostic uncertainty will lead more appropriate care decisions and ensure provision limited rehabilitation resources those likely benefit. Bedside markers covert residual cognition, including speech comprehension, may reduce this uncertainty.We recruited 28 patients acute were 2 7 days sedation-free failed commands....
The Vegetative and Minimally Conscious States (VS; MCS) are characterized by absent or highly disordered signs of awareness alongside preserved sleep-wake cycles. According to international diagnostic guidelines, cycles assessed means observations variable periods eye-opening eye-closure. However, there is little empirical evidence for true circadian cycling in these patients, have been no large-scale investigations the validity this criterion. We measured rhythms 55 VS MCS patients wrist...
Recent neuroscientific findings suggest that functional magnetic resonance imaging (fMRI)-based brain–computer interfaces may be a viable strategy for detecting covert awareness in patients clinically diagnosed as being vegetative state. This research open promising new avenue developing neuroimaging techniques provide prognostic and diagnostic information complements current behavioral tests assessing disorders of consciousness, thereby increasing the effectiveness screening. These also...
Functional neuroimaging of covert perceptual and cognitive processes can inform the diagnoses prognoses patients with disorders consciousness, such as vegetative minimally conscious states (VS;MCS). Here we report an event-related potential (ERP) paradigm for detecting a hierarchy auditory in group healthy individuals consciousness. Simple cortical responses to sounds were observed all 16 patients; 7/16 (44%) exhibited markers differential processing speech noise; 1 patient produced evidence...
Functional neuroimaging assessments of residual cognitive capacities, including those that support language, can improve diagnostic and prognostic accuracy in patients with disorders consciousness. Due to the portability relative inexpensiveness electroencephalography, N400 event-related potential component has been proposed as a clinically valid means identify preserved linguistic function non-communicative patients. Across three experiments, we show changes both stimuli task demands...