A5011941133- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Animal Virus Infections Studies
- Vaccine Coverage and Hesitancy
- Viral Infections and Outbreaks Research
- CRISPR and Genetic Engineering
- Viral gastroenteritis research and epidemiology
- Advanced Wireless Network Optimization
- Radioactive Decay and Measurement Techniques
- BIM and Construction Integration
- Dementia and Cognitive Impairment Research
- Water and Wastewater Treatment
- Underground infrastructure and sustainability
- Service and Product Innovation
- Energy and Environment Impacts
- Radiation Detection and Scintillator Technologies
- Industrial Engineering and Technologies
- Frailty in Older Adults
- vaccines and immunoinformatics approaches
- Atmospheric chemistry and aerosols
- Radiomics and Machine Learning in Medical Imaging
- Electric Power Systems and Control
- Power Systems and Technologies
Fudan University
2021-2024
Nanjing University of Posts and Telecommunications
2024
Anhui University of Finance and Economics
2022-2023
Huashan Hospital
2022
Shanghai Jiao Tong University
2015
Yanshan University
2012
Having adopted a dynamic zero-COVID strategy to respond SARS-CoV-2 variants with higher transmissibility since August 2021, China is now considering whether, and for how long, this policy can remain in place. The debate has thus shifted towards the identification of mitigation strategies minimizing disruption healthcare system case nationwide epidemic. To aim, we developed an age-structured stochastic compartmental susceptible-latent-infectious-removed-susceptible model transmission...
Abstract Genomic surveillance has shaped our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS-CoV-2 genomic and data using collection country-specific data. Here, we characterize increasing circulation the Alpha variant in early 2021, subsequently replaced by Delta around May 2021. sequencing availability varied markedly across countries, with 45 countries performing high level routine 96 sequencing. also...
In early March 2022, a major outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant spread rapidly throughout Shanghai, China. Here we aimed to provide description epidemiological characteristics and spatiotemporal transmission dynamics under population-based screening lockdown policies implemented in Shanghai.
An outbreak of COVID-19 caused by the SARS-CoV-2 Omicron BA.2 sublineage occurred in Shanghai, China from February 26 to June 30, 2022. We use official reported data retrieved Shanghai municipal Health Commissions estimate incidence infections, severe/critical and deaths assess disease burden. By adjusting for right censoring RT-PCR sensitivity, we provide estimates clinical severity, including infection fatality ratio, symptomatic case risk developing upon infection. The overall rate,...
Hundreds of millions doses coronavirus disease 2019 (COVID-19) vaccines have been administered globally, but progress on vaccination varies considerably between countries. We aimed to provide an overall picture COVID-19 campaigns, including policy, coverage, and demand vaccines.
Abstract Background Evidence on vaccine-specific protection over time, in particular against the Delta variant, and afforded by a homologous third dose is urgently needed. Methods We used previously published model neutralization data for five vaccines—mRNA-1273, BNT162b2, NVX-CoV2373, V01, CoronaVac— to evaluate long-term neutralizing antibody dynamics predict time-varying efficacy variant specific vaccine, age group, clinical severity. Results found that third-dose vaccination produces...
China has experienced a COVID-19 wave caused by Omicron XBB variant starting in April 2023. Our aim is to conduct retrospective analysis exploring the dynamics of outbreak under counterfactual scenarios that combine use vaccines, antiviral drugs, and nonpharmaceutical interventions.
Summary Background In early March 2022, a major outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant spread rapidly throughout Shanghai, China. Here we aimed to provide description epidemiological characteristics and spatiotemporal transmission dynamics under population-based screening lockdown policies implemented in Shanghai. Methods We extracted individual information on SARS-CoV-2 infections reported between January 1 May 31, timeline adopted...
This paper focuses on the value co-creation mechanism of "Liaoning Cuisine + Tourism" integration development model.Drawing Stimulus-Organism-Response (S-O-R) theoretical framework and theory, study empirically analyzes realization path consumers' participation in this tourism model constructs a dual mediation that incorporates both direct indirect effects. The research can provide support practical guidance for sustainable model.
Abstract Background Immunity after SARS-CoV-2 infection or vaccination has been threatened by recently emerged variants. A systematic summary of the landscape neutralizing antibodies against emerging variants is needed. Methods We systematically searched PubMed, Embase, Web Science, and 3 pre-print servers for studies that evaluated titers induced previous comprehensively collected individual data. calculated lineage-specific GMTs across different study participants types neutralization...
An outbreak of COVID-19 caused by the SARS-CoV-2 Omicron BA.2 sublineage occurred in Shanghai, China from February to June 2022. The government organized multiple rounds molecular test screenings for entire population, providing a unique opportunity capture majority subclinical infections and better characterize disease burden full spectrum clinical severity.
Background: Shanghai and Hong Kong, China, experienced an outbreak of COVID-19 in early 2022. Both cities had similar dynamic prevention policies population-level immunity, but showed differences the numbers cases deaths. Methods: We collected data from official websites to estimate compare infection rates, mortality fatality ratios (IFRs) between cities. further performed univariable analysis used two tree models explore factors affecting differences. Results: The rate was 42.45 (95% CI:...
The emergence of SARS-CoV-2 variants have raised concerns over the protective efficacy current generation vaccines, and it remains unclear to what extent, if any, different impact effectiveness various vaccines. We systematically searched for studies vaccine effectiveness, as well neutralization data variants, used a previously published statistical model predict against variants. Overall, we estimate mRNA-1273 ChAdOx1 nCoV-19 infection caused by Delta variant be 25-50% lower than that...
Abstract Evidence on vaccine-specific protection over time and boosting impact against the Delta variant across different clinical endpoints age groups is urgently needed. To address this, we used a previously published model, combined with neutralization data for four vaccines - mRNA-1273, BNT162b2, NVX-CoV2373, CoronaVac to evaluate long-term dynamics of neutralizing antibody predict time-varying efficacy by specific vaccine, group, severity. We found that booster vaccination produces...
Summary Background Hundreds of millions doses COVID-19 vaccines have been administered globally, but progress in vaccination varies considerably between countries. We aim to provide an overall picture campaigns, including policy, coverage, and demand vaccines. Methods conducted a descriptive study policy data obtained from multiple public sources as 23 October 2021. used these develop coverage indicators explore associations vaccine with socioeconomic healthcare-related factors. estimated...
Abstract China experienced a major nationwide wave of SARS-CoV-2 infections in December 2022, immediately after lifting strict interventions, despite the majority population having already received inactivated COVID-19 vaccines. Due to rapid waning protection and emergence Omicron XBB.1.5, risk another remains high. It is still unclear whether health care system will be able manage demand during this potential XBB.1.5 if number associated deaths can reduced level comparable that seasonal...
Abstract After the adoption of a dynamic zero-COVID strategy in China for nearly two years, whether and how long this policy can remain place is unclear. The debate has thus shifted towards identification mitigation strategies capable to prevent disruption healthcare system, should nationwide epidemic caused by SARS-CoV-2 Omicron variant start unfold. To aim, we developed mathematical model transmission tailored unique immunization epidemiological situation China. We find that level immunity...
Heterogeneous network is becoming more and crowded with a huge increment of users their diverse requirements today. Case exists when single cannot meet user's QoS requirement. To this end, we propose the concept "QoS demands splitting". When no channel can satisfy requirement, user connect to another simultaneously share his load. Our system model originated from satisfaction game, but split demand. approach Nash Equilibrium, satisfaction-guaranteed better reply algorithm. The convergence...
Abstract Background Genomic surveillance has shaped our understanding of SARS-CoV-2 variants, which have proliferated globally in 2021. Characterizing global genomic surveillance, sequencing coverage, the extent publicly available data coupled with traditional epidemiologic can provide evidence to inform and control strategies. Methods We collected country-specific on capabilities, public data, aggregated variant data. divided countries into three levels availability based predefined...