A5067815299- Reproductive Physiology in Livestock
- Drug Transport and Resistance Mechanisms
- Cytokine Signaling Pathways and Interactions
- Metabolism, Diabetes, and Cancer
- Click Chemistry and Applications
- Diet, Metabolism, and Disease
- Pharmacovigilance and Adverse Drug Reactions
- Diabetes Treatment and Management
- Pharmacy and Medical Practices
- Bacteriophages and microbial interactions
- Heat shock proteins research
- Extracellular vesicles in disease
- Traditional Chinese Medicine Studies
- Respiratory viral infections research
- Biosensors and Analytical Detection
- Genetic and phenotypic traits in livestock
- Natural Antidiabetic Agents Studies
- Ruminant Nutrition and Digestive Physiology
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Medicinal Plant Pharmacodynamics Research
- HER2/EGFR in Cancer Research
- Circular RNAs in diseases
- Pharmaceutical Practices and Patient Outcomes
- Biochemical effects in animals
Jilin University
2024-2025
Jilin Medical University
2025
Guangdong University of Technology
2024
Shanxi Medical University
2018-2021
Shaanxi Provincial People's Hospital
2018-2021
Background: Myocardial infarction (MI), a common presentation for cardiovascular disease, is caused by reduction of blood flow and oxygen supply one the main causes death worldwide. MicroRNAs participate in multiple physiological pathological processed play crucial role myocardial infarction. Results: qRT-PCR analysis showed that expression level miR-19a-3p was increased serum patient with MI. In vitro study indicated upregulated response to H2O2 treatment transferred exosome, then,...
Nonalcoholic steatohepatitis (NASH) is a combination of hepatic steatosis, inflammation, and fibrosis, it often follows simple steatosis in nonalcoholic fatty liver disease (NAFLD). However, no pharmacological treatment currently available for NASH. Given the important role TFEB (transcription factor EB) regulating macroautophagy/autophagy-lysosomal pathway, potentially novel therapeutic target NASH, which function can be regulated by AMP-activated protein kinase (AMPK) MTOR (mechanistic...
Bile acids are cholesterol-derived molecules that primarily produced in the liver. In nonruminants with fatty liver, overproduction of bile is associated liver injury. During transition period, a metabolic disorder can affect up to 50% high-producing dairy cows. The purpose this study was provide comprehensive evaluation hepatic acid metabolism cows by assessing expression changes genes involved synthesis, export, and uptake. serum activities aspartate aminotransferase, alanine glutamate...
During the periparturient period, both oxidative stress and inflammation of adipose tissue are considered high risk factors for metabolic disorder dairy cows. Oxidative can activate transcription factor nuclear kappa B (NF-κB), which lead to upregulation genes involved in inflammatory pathways. Thioredoxin 2 (TXN2) is a mitochondrial protein that regulates cellular redox by suppressing reactive oxygen species (ROS) generation nonruminant, whereas function TXN2 bovine adipocytes was unclear....
Respiratory pathogens pose a huge threat to public health, especially the highly mutant RNA viruses. Therefore, reliable, on-site, rapid diagnosis of such is an urgent need. Traditional assays as nucleic acid amplification tests (NAATs) have good sensitivity and specificity, but these require complex sample pre-treatment long test time. Herein, we present on-site biosensor for multiplex detection pathogens. Samples with viruses are first lysed in lysis buffer containing carrier release...
During the transition period, excessive negative energy balance (NEB) lead to metabolic disorders and reduced milk yield. Rumen microbes are responsible for resolving plant material producing volatile fatty acids (VFA), which primary source cows. In this study, we aimed investigate effect of citrus peel extract (CPE) supplementation on rumen microbiota composition, metabolism performance peripartum dairy
Objective To analysis the rationality of atorvastatin calcium and simvastatin in outpatient emergency departments from perspective drug interactions. Methods All prescrip-tions comprising Shaanxi Provincial People′s Hospital July 1 to December 31, 2017 were collected. The potential adverse interactions these prescriptions analyzed uses was determined by referring labels relevant domestic foreign guidelines. Results A total 3 647 collected, which 2 730 (74.9%) comprised 917...
Essential hypertension (EP) is a chronic disease. Effective treatment of one most crucial preventions cardiovascular (CV) and cerebrovascular (CBV) events. Enalapril folic acid combined with levamlodipine an effective therapy to treat EP, but its effect on CV CBV events in hypertensive patients unknown. This study set out assess the effects enalapril incidence EP. We randomly assigned 172 EP enrolled our hospital between April 2017 September 2018 receive Levoamlodipine Maleate Dispersible...