A5062981261- Agriculture Sustainability and Environmental Impact
- Asthma and respiratory diseases
- Mycotoxins in Agriculture and Food
- Animal Nutrition and Physiology
- Wheat and Barley Genetics and Pathology
- Ruminant Nutrition and Digestive Physiology
- Allergic Rhinitis and Sensitization
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Food Waste Reduction and Sustainability
- Gut microbiota and health
- Respiratory and Cough-Related Research
- Estrogen and related hormone effects
- Insect and Pesticide Research
- Reproductive Physiology in Livestock
- Fermentation and Sensory Analysis
- Horticultural and Viticultural Research
- Phytochemicals and Antioxidant Activities
- S100 Proteins and Annexins
- Potato Plant Research
- Animal Behavior and Welfare Studies
- Meat and Animal Product Quality
- Plant and fungal interactions
- Plant Disease Resistance and Genetics
- Digestive system and related health
- GABA and Rice Research
University of Milan
2000-2023
Università Cattolica del Sacro Cuore
2023
Centro di Ricerca per la Patologia Vegetale
2006
San Raffaele University of Rome
2000-2001
Aflatoxins (AFs) remain the main concern for agricultural and dairy industries due to their effects on performances quality of livestock production. are always unavoidable should be monitored. The objective this paper is bring light a significant volume data AF contamination in several animal feed ingredients Northern Italy. Regional Breeders Association Lombardy has been conducting survey program monitor mycotoxin feeds, paper, we present relating AFB1 contamination. In most cases (95%),...
We studied the effect of intravascular activation human neutrophils on synthesis cysteinyl leukotrienes (cysLT) and formation cerebral edema in guinea-pig brains. Challenge with chemotactic formylated tripeptide fMLP (0.1 microM) neutrophil-perfused brain vitro resulted blood-brain barrier disruption associated a significant increase cysLT. Both events were completely prevented by neutrophil pretreatment specific 5-lipoxygenase (5-LO) inhibitor. Perfusion 5-LO metabolite leukotriene B4 (10...
Polyphenolic grapevine components involved in plant resistance against pathogens possess various pharmacological properties that include nitric oxide (NO)-dependent vasodilation and anti-inflammatory free radical scavenging activities, which may explain the protective effect of moderate red wine consumption cardiovascular disease. The aim this work was (a) to verify possibility preharvest treatments with a activator, benzo-(1,2,3)-thiadiazole-7-carbothioic acid S-methyl ester (BTH), could...
Former food products (FFPs) have a great potential to replace conventional feed ingredients. This study aimed investigate the possibility partially standard ingredients with two different types of FFPs: bakery (FFPs-B) or confectionary (FFPs-C) FFPs and their effects on growth performances, digestibility metabolic status in post-weaning piglets. Thirty-six piglets were randomly assigned three experimental diets (n = 12 per diet) for 42 days: diet (CTR), where 30% replaced by (FFPs-B)....
We studied the effect of endogenous and exogenous prostaglandin E2 (PGE2), a metabolite arachidonic acid through cyclooxygenase (COX) pathway, on interleukin (IL)-1 β –induced COX-2 expression, using primary cultures human bronchial smooth-muscle cells (HBSMC). Treatment with PGE2 resulted in enhanced expression IL-1 protein messenger RNA (mRNA) as compared cytokine per se. Inhibition production nonselective COX inhibitor (flurbiprofen, 10 μ M) significant reduction – induced supporting role...
Cysteine-containing leukotrienes (cysteinyl-LTs) are potent bronchoconstrictors and play a key role in asthma. We found that histamine LTD4 markedly constrict strips of human bronchi (HB) with similar efficacy. However, airway smooth-muscle (HASM) cells, LTD4, at variance histamine, elicited only small, transient change intracellular calcium ion concentration. HASM cells express both Ca2 +-dependent -independent isoforms protein kinase C (PKC) (i.e., PKC- α ). Western blot analysis showed is...
This review addresses the potential role of antioxidants and methyl-group sources in optimising metabolic health dairy ruminants. The productivity high-yielding cows has increased over past 40 years milk yield doubled. Such increases production have been observed not only but also to some extent other ruminants such as ewes, goats buffaloes (Bubalus bubalis). As a consequence, all specialized it is essential optimize macro micro-nutrient supply, especially during most critical period...
Awareness of the need to improve sustainability livestock by reducing loss natural resources has increased significantly. This study investigated effects two categories food industry leftovers, also referred as former foodstuff products (FFPs), on pig gut microbiota and intestinal volatile fatty acid (VFA) production. Thirty-six female postweaning piglets (28 days old, Large White × Landrace, 6.5 ± 1.1 kg) were separated into three groups fed a conventional diet (CTR), diets in which cereals...
Fusarium mycotoxins are inactivated by rumen flora; however, a certain amount can pass the and reticulum or be converted into biological active metabolites. Limited scientific evidence is available on impact mitigation of dairy cows' performance health, particularly when cows exposed for an extended period (more than 2 months). The information related to these mycotoxin effects milk cheese-making parameters also very poor. objective this study was evaluate commercially product (MMP, i.e.,...
We measured urinary 8-isoprostane (IsoP), a biomarker of oxidative stress, and fractional exhaled nitric oxide (FeNO), airway inflammation, in 8 patients with COPD who were current smokers (COPD CS) (7/1 males/females, age 60±4 yrs, mean±SEM, FEV1 65.8±4.8% pred), 9 ex-smokers ES) (7/2 66±3 FEV 50.6±3.6% 10 1 healthy (HS) (9/1 m/f, 43±4 101.7±3.1% pred). also prostaglandin (PG)E2, that can have proand anti-inflammatory effects, sputum supernatants 6 CS (5/1 60±5 62.9±4.4% 12 ES (10/2 67±2...