A5056400725- Vaccine Coverage and Hesitancy
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Bacterial Infections and Vaccines
- Influenza Virus Research Studies
- Viral Infections and Immunology Research
- Healthcare Systems and Public Health
- Pneumonia and Respiratory Infections
- Pediatric health and respiratory diseases
- Respiratory viral infections research
- Human Health and Disease
- Viral gastroenteritis research and epidemiology
- Zoonotic diseases and public health
- Virology and Viral Diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Child and Adolescent Health
- COVID-19 epidemiological studies
- Yersinia bacterium, plague, ectoparasites research
- Medical Device Sterilization and Disinfection
- Tuberculosis Research and Epidemiology
- Diphtheria, Corynebacterium, and Tetanus
- Medical and Biological Sciences
- Intramuscular injections and effects
- Global Healthcare and Medical Tourism
Perm State Medical Academy
2013-2025
Ministry of Health of the Russian Federation
2018-2022
Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
2021
Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
2021
Republican Scientific and Practical Center of Cardiology
2021
Candid
2021
Russian Academy of Sciences
2021
Perm State University
2021
Krasnoyarsk State Medical University
2019
Regional Center for Prevention and Control of AIDS and Infectious Diseases
2001
The Doctrine for the prevention of health с are-associated Infections (HAIs) is a declaration state policy in field epidemiological safety medical care. This system views and provisions that establishes direction HAIs, ways forms their implementation. presence deeply developed doctrine makes it possible to have basis decision-making. According conclusion experts from World Health Organization, no type healthcare settings any country can claim be free risk HAIs. Four key underpin risk-based...
Relevance . The National vaccination schedule (NVS) of the Russian Federation includes 12 infections against 17–18 indicated in Vaccination Schedules most EU countries, and requires improvement terms expanding number contingents subject to immunization, which is reflected «Strategy for development vaccine prevention infectious diseases period up 2035» roadmap its implementation. Since process entry new vaccines into NVS quite «difficult» economically costly (development domestic vaccines,...
Global polio eradication requires both safe and effective vaccines, production processes. Sabin oral poliomyelitis vaccine (OPV) strains can evolve to virulent viruses result in outbreaks, conventional inactivated (Salk-IPV) includes accumulation of large stocks neurovirulent wild polioviruses. Therefore, IPV based on attenuated OPV seems a viable option. To increase the global supply affordable still not-polio free world we developed an made from strains–PoliovacSin. Clinical trials...
The article presents the basic positions of managing vaccine prevention risks on population level. science-based necessity transition from assessment effectiveness mass vaccinal in terms incidence rates to potential prevention. prospects for further development this methodology were determined.
Detection of post-vaccination complications with the subsequent investigation causes and measures to prevent their occurrence increases perception immunization society improves health care. This is primarily coverage, which leads lower morbidity. The purpose this article offer for discussion a new algorithm registration diseases postvaccination period, based on synthesis existing national system modern international approaches.
The development of theoretical concept is based on previous knowledge. In this article we have presented historical aspect epidemiology healthcare-associated infections (HAIs), because without these events the modern scientific basis for prevention HAIs would not be possible. will in second part article.
Healthcare workers are one of the main risk groups for COVID-19 infection and should be provided priority protection. Objective. To examine development dynamics epidemic process manifestations in healthcare as well to assess efficacy intranasal human recombinant interferon alpha-2b (Grippferon®) emergency medicationassisted nonspecific prevention novel coronavirus infection. Patients methods. The incidence Perm was examined using official statistical data dynamics. prophylactic Grippferon®...
It is indicated in the article importance of vaccine confidence population, medical workers, media, and bodies authority. The necessary for implementation prevention at population level national security. risk-communication concept to ensure adherence all segments are present. main directions activities given.
The results of foreign and Russian author`s researches about immunization adult population are presented in article. analysis the vaccinal prevention state infectious diseases adults different countries world (national guidance on immunization, coverage preventive vaccinations, financing mechanisms) is given. tasks improving Russia defined.
Introduction. Rotavirus infection (RVI) is the most common cause of severe gastroenteritis in infants and young children worldwide: 600,000 die annually; it accounts for approximately 3 million hospitalizations 25 physician visits each year among children. Preventive vaccination universally recognized as effective measure against this infection.The purpose study assessment reactogenicity, safety immunogenicity pentavalent live vaccine RVI prevention childhood immunization.Materials methods....
Relevanc. Measles, mumps and rubella, despite many years of vaccination, retain their epidemiological social significance at the present time. The aim work is to study safety immunogenicity. Of vaccine for prevention measles, rubella Vactrivir® in children's immunization. Materials methods. immunogenicity was studied a simple multicenter blind comparative randomized clinical trial involving children aged 12 months 6 years. Results. characterized by low reactogenicity, high profile comparable...
Nosocomial infections (NIs) are the most important components of problems to assure medical care quality and create a safe hospital environment. Today there has been need for revision 1999 program document The nosocomial prevention concept that is determined by following factors: objective processes public health sanitary epidemiologic service reformation in country; new research data on specific features epidemiology epidemic process NIs facilities (HCFs) different profile; revaluation...
Background. Vaccination is considered by the world community as main measure of fight against pneumococcal infection [1–3]. Immunization children has been carried out since end 2014. Goals. To study compliance vaccination scheme in young and its influence on efficacy. Methodology. Evaluation schedule impact morbidity was under conditions epidemiological observational descriptive analytical («cohort») researches. Expert assessment made medical records 52 patients, 200 electronic cards...
The article presents the results of an open comparative randomized clinical study on assessment reactogenicity, safety and immunogenicity domestic vaccine "EntseVir®" with reduced antigenic load in immunization children aged 3 to 17 years schedule for 0-60 days. is characterized by low high profile immunogenicity. On main indices, it not inferior foreign «FSME-Immun Inject / Junior».
Relevance Hepatitis B and tuberculosis are a serious global health problem. Babies under one at high risk of severe form these diseases mortality. Immunization newborns plays key role both in the individual prevention hepatitis reducing burden infections general. The purpose study was to assess timeliness vaccination against determine causes deviations from national vaccine schedule. Materials methods. coverage studied according case history (form No. 097/у, N = 672) 6 «Information on...
BACKGROUND: The need for microbiological monitoring of the distribution pneumococcal serotypes is associated with changes that occur during routine immunization children vaccines. AIM: To characterize in serotype structure Streptococcus pneumoniae obtained from healthy preschool between 2016 and 2022. MATERIALS AND METHODS: In total, 1250 aged 6 years attending kindergartens were examined multicenter studies (2016–2018 2020–2022). Nasopharyngeal isolates (n=265) using culture method. S. was...
The article presents the results of open comparative randomized clinical study performed in children aged 3 to 17 years which were immunized with Russian vaccine «EnceVir»® possessing reduced antigenic load accordingly emergency vaccination protocol. aim was assess reactogenicity, safety and immunogenicity vaccine. is characterized by a low reactogenicity profile, high profile safety, adequate immunogenicity, it not yielding foreign «FSME-Immun Inject / Junior»
At present it is impossible to develop epidemiologic surveillance and control over any infection regarding studies on dynamics of morbidity, seasonality periodicity without using mathematical modeling techniques. Our research goal was study regularities in manifestations epidemic process for enterovirus (non-polio) (EVnI) the Russian Federation 14 years (2006–2019) models (linear, logarithmic, power, exponential approximation).An optimal model selected three statistical parameters, namely...
A research objective – definition of the main directions improvement epidemiological control a pertussis on basis studying manifestations epidemic process and its determinants. Materials methods . The analysis incidence is carried out according to official statistics in 19 years, population antipertussoid immunity studied by results routine serological monitoring specially organized screening researches. At discussion development recommendations WHO published articles domestic foreign...
Relevance . Pneumococcal disease remains an urgent public health problem, despite mass immunization of infants and young children. The impact children’s universal vaccination on the morbidity etiological structure in various clinical forms infection unclear children adults. Аim Тo evaluate herd effect with a 13-valent conjugated pneumococcal vaccine. Materials Methods prophylactic efficacy is studied within comparative retrospective epidemiological analysis incidence rates bacterial...
Relevance . The need to create a domestic pneumococcal polyvalent vaccine is one of the main directions «Strategy for development prevention infectious diseases period up 2035». Aim To evaluate immunological efficacy and safety polysaccharide conjugate adsorbed thirteen-valent (PCV13) in immunization adults children theRussian Federation. Materials methods conjugated were studied prospective comparative randomized double-blind study parallel groups adult volunteers aged 18 65 years...
Relevance Hepatitis B and tuberculosis are a serious global health problem. Babies under one at high risk of severe form these diseases mortality. Immunization newborns plays key role both in the individual prevention hepatitis reducing burden infections general. The purpose study was to assess timeliness vaccination against determine causes deviations from national vaccine schedule. Materials methods. coverage studied according case history (form No. 097/у, N = 672) 6 «Information on...