Water-soluble fullerene derivatives are actively investigated as potential drugs for cancer treatment due to their favorable membranotropic properties. Herein, cytotoxic effects of twenty with different solubilizing addends were evaluated in three types non-small-cell lung carcinoma (NSCLC). The structural descriptors the related inhibitory activities on each type cell by quantitative structure-activity relationship (QSAR) approach. determination coefficient

Betel quid (BQ) is a favorite chewing item among many communities in different parts of Asia where it popular by names. BQ unique combination nut or fruit from the Areca catechu Linn. (AN) tree, leaf Piper betle (BL) vine, slaked lime, paste bark Acacia tree and other spices. AN has been used successfully various traditional medicines civilizations over several ages. Initially condemned medical for its health hazards, identification application potent pharmacologically bioactive compounds...

Average daily gain (ADG) and feed efficiency (FE) are important factors for assessing productivity in farm animals. Myostatin (MSTN), previously called GDF8, is a member of transforming growth factor β (TGFβ) superfamily. It negative regulator both embryonic development adult homeostasis skeletal muscle. In this study, the genotypes MSTN g.435G > A g.447A G SNPs Duroc pigs were determined. The 435GG/447AA individually had significantly higher ADG (P < 0.01), body weight at 70 d 0.05) 150...

According to pigeon racing rules in Taiwan, the raiser must decide which juveniles will be chosen as soon possible. Differentiating sex of young pigeons based on appearances, and other traditional methods, can time-consuming require several pieces equipment. Recombinase polymerase amplification (RPA) combined with a lateral-flow dipstick (LFD) could further simplify presentation results. A designed reverse primer probe were labeled biotin FAM (fluorescein), respectively, serve ligands LFD....

The aim of this study was to create a set microsatellite markers with high polymorphism for the genetic monitoring and structure analysis local goose populations.

In recent years, the population size of Taiwan yellow cattle has drastically declined, even become endangered. A preservation project, Yellow Cattle Genetic Preservation Project (TYCGPP), was carried out at Livestock Research Institute (LRI) Hengchun branch (1988–present). An analysis intra- and inter- variability performed to be first step preserve this precious genetic resource. work, a total number 140 individuals selected from five populations were analyzed using 12 microsatellite...

Tetranectin (TN), a plasminogen-binding protein originally involved in fibrinolysis and bone formation, was later identified as secreted adipokine from human rat adipocytes positively correlated with adipogenesis lipid metabolism adipocytes. To elucidate the nutritional regulation of adipogenic TN diets containing different sources fatty acids (saturated, n-6, n-3) adipocytes, we cloned coding region porcine cDNA library analyzed tissue expressions weaned piglets fed 2% soybean oil (SB,...

A set of microsatellite markers with high polymorphism from Tsaiya duck were used for the genetic monitoring and structure analysis Brown White populations in Taiwan.

Laboratory rabbits used in Taiwan are primarily supplied by the Livestock Research Institute (LRI) and Animal Drugs Inspection Branch (ADIB) of Health Institute. An analysis genetic characteristics structure these populations would thus be a fundamental step building long-term management programme for maintaining stable animal quality preserving variation among populations. In this study, DNA samples were isolated from founders 5 populations: New Zealand White (NZW) Japanese (JPN) ADIB, NZW...

Caprine arthritis and encephalitis (CAE) is an economically important viral disease that causes chronic inflammatory in goats.At present, the diagnosis of caprine arthritis-encephalitis virus (CAEV) infection usually obtained through serological testing or molecular techniques, while agar gel immunodiffusion test (AGID) enzyme-linked immunosorbent assay (ELISA) focus on detection CAEV antibodies, PCR isothermal amplification methods directly detect proviral sequence CAEV.The use Western blot...

Alongside the rise of animal-protection awareness in Taiwan, public has been paying more attention to dog genetic deficiencies due inbreeding pet market. The goal this study was isolate novel microsatellite markers for monitoring structure domestic populations Taiwan.A total 113 DNA samples from three breeds-beagles (BEs), bichons (BIs), and schnauzers (SCs)-were used subsequent polymorphic tests applying 14 that were isolated study.The results showed high level diversity observed these...

Pedigree analysis was performed in three major Taiwanese swine breeds to evaluate the genetic variability current population and determine main reason for diversity (GD) loss after occurrence of foot-and-mouth disease (FMD) Taiwan. The pedigree files Duroc, Landrace, Yorkshire breeds, containing 60,237, 87,177, 34,373 records, respectively, were analyzed. We divided into two subpopulations (pre-1998 post-1998) role FMD GD loss. completeness related indicators analyzed quality, several...

Frequency-dependent terahertz (THz) penetration depth is experimentally assessed using a multilayered water-skin model. The skin adsorbed with one water overlayer considered as the structure to reflect THz waves and reflected field variation observed during desorption process. depths can thus be derived model while considering measured reflectivity, dielectric constants, effective thicknesses of overlayer. largest independent illumination power wave in 0.4-0.6 at approximately 0.3 mm,...

In cattle and other species, mutations polymorphisms of the myostatin (MSTN) gene are related to ”double-muscled” phenotype. Polymorphisms in MSTN promoter region at 435 / 447 sites candidate genetic markers for regulating expression also myogenic process. The purpose this study was determine variations porcine 435/447 region. Our data showed pig varied among different breeds. DNA sequencing, TaqMan SNP genotyping assays PCR-RFLP results indicated three genotypes, AA, AG GG were detected...

Abstract The Formosan pangolin ( Manis pentadactyla ) is an endangered species in Taiwan. polymorphisms at major histocompatibility complex (MHC) gene regions could provide indicator for immunological fitness and genetic diversity of a population. In this study, seven different novel markers MHC genotyping were developed used to evaluate the 92 pangolins. markers, six loci showed monomorphism or only two haplotypes. Only one marker, DLA class II DR-1 beta chain-like locus, more diversity:...