A5018745751- Bioinformatics and Genomic Networks
- Gender, Labor, and Family Dynamics
- Work-Family Balance Challenges
- Intergenerational Family Dynamics and Caregiving
- Family Dynamics and Relationships
- Gene expression and cancer classification
- Gene Regulatory Network Analysis
- Health disparities and outcomes
- COVID-19 and Mental Health
- Housing, Finance, and Neoliberalism
- Circular RNAs in diseases
- Retinoids in leukemia and cellular processes
- Genomics and Chromatin Dynamics
- RNA and protein synthesis mechanisms
- DNA Repair Mechanisms
- Computational Drug Discovery Methods
- Renal and related cancers
- Employment and Welfare Studies
- Cancer-related Molecular Pathways
- MicroRNA in disease regulation
- Psychological Well-being and Life Satisfaction
- Biomedical Text Mining and Ontologies
- Semantic Web and Ontologies
- Epigenetics and DNA Methylation
- Sleep and related disorders
Institute of Sociology, Academia Sinica
2023
University of Southampton
2020-2022
Academia Sinica
2022
The University of Texas at Austin
2016
Chien Hsin University of Science and Technology
2011-2016
National Cheng Kung University
2006-2007
Abstract Objective This study evaluates the role of objective and subjective measures economic uncertainty, as well furlough schemes, on changes in couples' relationships during first lockdown UK. Background Most theories relationship quality argue that uncertainty strains intimate relationships, leading to a deterioration quality. Few studies capture such an intense period government policy mitigate impact crisis. Method The employs UK Household Longitudinal Covid‐19 surveys conducted...
ABSTRACT Transcription factor CCAAT/enhancer‐binding protein delta (CEBPD) plays multiple roles in tumor progression. Studies have demonstrated that cisplatin (CDDP) induced CEBPD expression and had led to chemotherapeutic drug resistance. However, the underlying molecular mechanisms of CDDP‐regulated its relevant CDDP responses remain elusive. MicroRNAs (miRNAs) are small non‐coding RNAs negatively regulate gene a sequence‐specific manner. Abnormal miRNAs is associated with In current...
Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute our understanding biology as well developments new diagnose and therapies. Several mathematical models have been used explore the phenomena transcriptional mechanisms in Saccharomyces cerevisiae. However, contemplating on controlling feed-forward feedback loops not resolved adequately cerevisiae, nor human cells. In this study, we introduce a Genetic Algorithm-Recurrent...
Resistance to chemotherapy severely limits the effectiveness of drugs in treating cancer. Still, mechanisms and critical pathways that contribute resistance are relatively unknown. This study elucidates chemoresistance-associated retrieved from integrated biological interaction networks identifies signature genes relevant for resistance.An network was constructed by collecting multiple metabolic interactions public databases k-shortest path algorithm implemented identify chemoresistant...
Heterosexual unions and parenthood are key contributors to gender inequality in housework. Over the last two decades, social meaning of partnership has changed. This study investigated whether this change narrative status influenced changes housework gap. Using American Time Use Survey 2003–2005 2013–2015, findings show that gap was larger for people a couple relationship than singles. For nonparents, no difference between those married cohabiting. Gender persisted among parents but...
While prior studies have examined sleep across the lifecourse, few investigated around birth of a child, one most important events to cause deprivation. This study investigates changes in hours and quality, paying attention differences by gender partnership status. Using UK Household Longitudinal Study, we follow approximately 1,000 participants as they transition into parenthood three-year window. We use OLS logistic regression analyze quality. Results suggest that women's is reduced an...
People in East and South Asia widely believe that having children brings fulfilment to an individual’s life. However, over the past fifty years, modernisation has been accompanied by a remarkable drop birth rates level even lower than most western countries. Prior research on nations shown time demands financial stresses of parenthood, as well current inflexible employment practices, contribute high cost parenthood discount emotional rewards children. This study investigates happiness...
Cells continuously recycle their gene expressions. In order to understand the expressions of cell cycle-regulated genes, time series expression profiles provide a more complete picture than single point profiles. However, these raise new challenges for computer scientists and statisticians. One is reconstruction regulatory connections between proteins, or other products. Recently, some analytic methodology techniques have been constructed model such data discover networks. But most...