A5089829985- Monoclonal and Polyclonal Antibodies Research
- Biotin and Related Studies
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Epigenetics and DNA Methylation
- Genetic Associations and Epidemiology
- Adolescent and Pediatric Healthcare
- Cancer-related gene regulation
- Birth, Development, and Health
- Drug Transport and Resistance Mechanisms
- Mast cells and histamine
- Complement system in diseases
Jilin University
2018-2019
Background/Aims: Schizophrenia is a severe psychiatric disorder, and complement 3 (C3) closely related to schizophrenia. We investigated the association between C3 polymorphisms schizophrenia in Northeast Han Chinese population. Methods: A total of 2240 people, consisting 1086 patients with 1154 healthy controls, were recruited for this study. Ten single nucleotide (SNPs; rs11569562, rs344555, rs2241393, rs2241392, rs11569514, rs445750, rs451760, rs11672613, rs2230205, rs2250656) selected...
Recent research has shown that prenatal famine exposure may be one of the risk factors for schizophrenia and people born in years at an increased due to alteration DNA methylation genes. In this study, association rs2283291/rs4648635 incidence genetic level were investigated provide clues pathogenesis schizophrenia. A total 960 participants recruited, comprising 473 famine-exposed individuals (225 patients 248 controls) 487 non-famine-exposed (220 267 controls). The famine, schizophrenia,...
Background Schizophrenia (SCZ) is a complex and severe mental illness. There lack of effective biomarkers for SCZ diagnosis. The aim this study was to explore the possibility using serum peptides diagnosis as well analyze association variants in genes coding these SCZ. Methods After bead-based fractionation, matrix-assisted laser desorption ionization/time-of-flight mass spectrometry technique used identify that showed different expressions between 166 patients 201 healthy controls....
To investigate the relationship between polymorphism of related gene loci miRNAs regulated fibrinopeptide A and schizophrenia. Lay foundation for aetiology schizophrenia.Adapt to phase match sex age case-control study, a total 513 Chinese Han patients with schizophrenia were selected as case group, normal healthy persons control group. Obtaining SNPs information FGA by querying dbSNP database, reference HapMap database included site frequency screening. The distributions genotyped iMLDR® SNP...